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Gene clusters-based pathway enrichment analysis identifies four pan-cancer subtypes with distinct molecular and clinical features
Gene clusters-based pathway enrichment analysis identifies four pan-cancer subtypes with distinct molecular and clinical features
Pathways-based clustering methods have been proposed to explore tumor heterogeneity. However, such methods are currently d...
Serine related gene CCT6A promotes metastasis of hepatocellular carcinoma via interacting with RPS3
Serine related gene CCT6A promotes metastasis of hepatocellular carcinoma via interacting with RPS3
Metastasis is responsible for approximately 90% of lethality from solid tumors. Metabolic abnormalities are one of the key...
Xuanhong Dingchuan Tang suppresses bronchial asthma inflammation via the microRNA-107-3p/PTGS2/MAPK axis
Xuanhong Dingchuan Tang suppresses bronchial asthma inflammation via the microRNA-107-3p/PTGS2/MAPK axis
This study aimed to investigate the mechanism of Xuanhong Dingchuan Tang (XHDCT) in delaying bronchial asthma inflammation...
Barley stripe mosaic virus-induced gene silencing for functional validation of abiotic stress in barley
Barley stripe mosaic virus-induced gene silencing for functional validation of abiotic stress in barley
The barley stripe mosaic virus (BSMV) uses its genomic RNA components (alpha, beta, and gamma) as an efficient method for ...
Unraveling the organellar genomic landscape of the therapeutic and entheogenic plant Mimosa tenuiflora: insights into genetic, structural, and evolutionary dynamics
Unraveling the organellar genomic landscape of the therapeutic and entheogenic plant Mimosa tenuiflora: insights into genetic, structural, and evolutionary dynamics
Mimosa tenuiflora, popularly known as “Jurema-Preta”, is a perennial tree or shrub native to the tropical regi...
Circular RNAs in the pathogenesis of SARS-CoV-2: potential diagnostic biomarkers and therapeutic targets
Circular RNAs in the pathogenesis of SARS-CoV-2: potential diagnostic biomarkers and therapeutic targets
Since December 2019, the global dissemination of a novel coronavirus has precipitated a notable public health crisis, prom...
Towards assembling functional cyanobacterial β-carboxysomes in Oryza sativa chloroplasts
Towards assembling functional cyanobacterial β-carboxysomes in Oryza sativa chloroplasts
The major limiting factor of photosynthesis in C3 plants is the enzyme, rubisco which inadequately distinguishes between c...
A cutting-edge investigation of the multifaceted role of SOX family genes in cancer pathogenesis through the modulation of various signaling pathways
A cutting-edge investigation of the multifaceted role of SOX family genes in cancer pathogenesis through the modulation of various signaling pathways
This detailed study examines the complex role of the SOX family in various tumorigenic contexts, offering insights into ho...
Epigenetic modification mediated by PHF20/METTL14/HOXA13 signaling axis modulates osteogenic differentiation of mesenchymal stem cells
Epigenetic modification mediated by PHF20/METTL14/HOXA13 signaling axis modulates osteogenic differentiation of mesenchymal stem cells
This study investigates the mechanism of PHF20 in osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs)...
Application of a high-throughput swarm-based deep neural network Algorithm reveals SPAG5 downregulation as a potential therapeutic target in adult AML
Application of a high-throughput swarm-based deep neural network Algorithm reveals SPAG5 downregulation as a potential therapeutic target in adult AML
Gene‒gene interactions play pivotal roles in disease pathogenesis and are fundamental in the development of targeted...
Impact of structural variations and genome partitioning on bread wheat hybrid performance
Impact of structural variations and genome partitioning on bread wheat hybrid performance
The agronomical interest of hybrid wheat has long been a matter of debate. Compared to maize where hybrids have been succe...
pmiRScan: a LightGBM based method for prediction of animal pre-miRNAs
pmiRScan: a LightGBM based method for prediction of animal pre-miRNAs
MicroRNAs (miRNA) are categorized as short endogenous non-coding RNAs, which have a significant role in post-transcription...
Transcription factor MAZ activates the transcription of hypomethylated TYMP in ccRCC
Transcription factor MAZ activates the transcription of hypomethylated TYMP in ccRCC
Clear cell renal cell carcinoma (ccRCC) is a highly malignant tumor characterized by a significant prope...
Unraveling the potential mechanism and prognostic value of pentose phosphate pathway in hepatocellular carcinoma: a comprehensive analysis integrating bulk transcriptomics and single-cell sequencing data
Unraveling the potential mechanism and prognostic value of pentose phosphate pathway in hepatocellular carcinoma: a comprehensive analysis integrating bulk transcriptomics and single-cell sequencing data
Hepatocellular carcinoma (HCC) remains a malignant and life-threatening tumor with an extremely poor prognosis, posing a s...
Narciclasine attenuates sepsis-associated acute kidney injury through the ESR1/S100A11 axis
Narciclasine attenuates sepsis-associated acute kidney injury through the ESR1/S100A11 axis
Narciclasine (Ncs) was effective in sepsis management due to its antioxidant properties. The present study dissected the p...
Elucidating circRNA-miRNA-mRNA competing endogenous regulatory RNA network during leaf rust pathogenesis in wheat (Triticum aestivum L.)
Elucidating circRNA-miRNA-mRNA competing endogenous regulatory RNA network during leaf rust pathogenesis in wheat (Triticum aestivum L.)
Advancements in bioinformatic tools and breakthroughs in high throughput RNA sequencing have unveiled the potential role o...
Hypertension Management to Reduce Racial/Ethnic Disparities: Clinical and Community-Based Interventions
Hypertension Management to Reduce Racial/Ethnic Disparities: Clinical and Community-Based Interventions
Hypertension remains a major public health concern globally and in the United States with significant racial/ethnic dispar...
Augmented Reality in Cardiology: Enhancing Visualization and Precision
Augmented Reality in Cardiology: Enhancing Visualization and Precision
With the recent advances in augmented reality (AR), cardiologists can better understand three-dimensional (3D) cardiac ana...
App-Timizing Cardiac Rehabilitation: Enhancing Patient Engagement with Mobile Health Applications
App-Timizing Cardiac Rehabilitation: Enhancing Patient Engagement with Mobile Health Applications
This manuscript examines how mobile health (mHealth) applications (apps) can enhance patient engagement in cardiac rehabil...
Artificial Intelligence Across the Continuum of Atrial Fibrillation Screening, Diagnosis, and Treatment
Artificial Intelligence Across the Continuum of Atrial Fibrillation Screening, Diagnosis, and Treatment
The review aims to help clinicians understand the current landscape of artificial intelligence (AI) tools for atrial fibri...
Physical Activity Barriers, Facilitators, and Preferences in Rural Adults with Obesity
Physical Activity Barriers, Facilitators, and Preferences in Rural Adults with Obesity
To identify physical activity-related barriers, facilitators, and preferences among adults with obesity living in rural ar...
Mitral Valve Dysplasia: An Updated Review
Mitral Valve Dysplasia: An Updated Review
The purpose of this manuscript is to provide a comprehensive review for the clinician regarding the epidemiology, pathophy...
Understanding the Significance and Approach to Ventricular Tachycardia Ablation of Scar-related Border Zones
Understanding the Significance and Approach to Ventricular Tachycardia Ablation of Scar-related Border Zones
Ventricular arrhythmias in non-ischemic cardiomyopathies can be uniquely challenging to manage with a higher rate of unsuc...
Racial and Ethnic Disparities in Heart Failure with Preserved Ejection Fraction: Epidemiology, Diagnosis, Management and Outcomes
Racial and Ethnic Disparities in Heart Failure with Preserved Ejection Fraction: Epidemiology, Diagnosis, Management and Outcomes
This review discusses the state of racial and ethnic inequities in heart failure with preserved ejection fraction (HFpEF) ...
The role of transforming growth factor β in cervical carcinogenesis
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Impact of chronic stress on intestinal mucosal immunity in colorectal cancer progression
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Cholecystokinin and gastrin as immune modulating hormones: Implications and applications
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Central role of Galectin-3 at the cross-roads of cardiac inflammation and fibrosis: Implications for heart failure and transplantation
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Molecular mechanisms of regulation of IL-1 and its receptors
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Ubiquitination in pyroptosis pathway: A potential therapeutic target for sepsis
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