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England poised to green-light precision breeding
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A laboratory-evolved CRISPR-associated transposase adapts to human cells
CRISPR-associated transposases (CASTs) are an attractive candidate for genome editing applications, as they enable the ins...
FDA says GM pigs safe to eat
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Infant receives the first customized CRISPR therapy
Base and prime editors promise to correct nearly all known pathogenic variants, but their therapeutic development is restr...
CRISPR-TO directs RNA to defined intracellular locations
Although spatial RNA organization is central to cellular functions and disease mechanisms, its functional consequences rem...
Court reignites CRISPR patent dispute
The University of California and the University of Vienna have convinced a U...
Preliminary evaluation of a new prototype interferon-gamma release assay for the detection of –specific T-cell responses in patients with tuberculosis
Preliminary evaluation of a new prototype interferon-gamma release assay for the detection of –specific T-cell responses in patients with tuberculosis
Screening for tuberculosis infections (TBI) using the tuberculin skin test or interferon-gamma release assays (IGRA) is cr...
New insights and perspectives on the virulence of hypervirulent
New insights and perspectives on the virulence of hypervirulent
Klebsiella pneumoniae, a Gram-negative bacterium, comprises strains with diverse virulence potentials, ranging from classi...
The relationship between the skin microbiome and probiotics in the healing of burn injuries
The relationship between the skin microbiome and probiotics in the healing of burn injuries
The relationship between the skin microbiome and probiotics in the healing of burn injuries has garnered significant atten...
Inhibitory effects of strain I300 against adhesion, invasion, and inflammatory response in gastric epithelial cells in vitro
Inhibitory effects of strain I300 against adhesion, invasion, and inflammatory response in gastric epithelial cells in vitro
The increasing rate of Helicobacter pylori (H. pylori) antibiotic resistance has attenuated the effectiveness of conventio...
The response surface method enables efficient optimization of induction parameters for the production of bioactive peptides in fed-batch bioreactors using
The response surface method enables efficient optimization of induction parameters for the production of bioactive peptides in fed-batch bioreactors using
The production of recombinant peptides is critical in biotechnology and medicine for treating a variety of diseases. Thus,...
Purification and activity enhancement of extracellular tyrosinase from a protease-silenced zygomycete strain
Purification and activity enhancement of extracellular tyrosinase from a protease-silenced zygomycete strain
The intra- and extra-cellular monophenolase and diphenolase activities of the tyrosinase produced by Amylomyces rouxii wer...
Evaluation of native strains possessing nematicidal specific genes against
Evaluation of native strains possessing nematicidal specific genes against
Plant-parasitic nematodes, including root-knot nematodes, are phyto-parasites that cause significant crop damage and econo...
Molecular characterisation of fosfomycin resistance genes in isolates
Molecular characterisation of fosfomycin resistance genes in isolates
Fosfomycin is a well-known antibiotic that exhibits broad-spectrum activity against various bacterial pathogens, including...
Biological activities of citrus fruit-derived copper oxide nanoparticles: towards sustainable antimicrobial and antioxidant solutions
Biological activities of citrus fruit-derived copper oxide nanoparticles: towards sustainable antimicrobial and antioxidant solutions
The synthesis of CuO NPs from Citrus fruit peel waste is a noteworthy strategy for the effective repurposing utilization o...
DnaK interacts with bovine transferrin, lactoferrin, and hemoglobin as a putative iron acquisition mechanism
DnaK interacts with bovine transferrin, lactoferrin, and hemoglobin as a putative iron acquisition mechanism
Ovine epididymitis, caused by Actinobacilus seminis, is an infectious disease that produces atrophy of the testis, low fer...
Insight on long non-coding RNA expression profile in THP-derived macrophages infected by H37Rv, H37Ra, and BCG
Insight on long non-coding RNA expression profile in THP-derived macrophages infected by H37Rv, H37Ra, and BCG
Emerging evidence has suggested a potential role for long non-coding RNAs (lncRNAs) in transcriptome dysregulation during ...
Pichia Toolkit: Use of the combinatorial library screening system for expression of a marine laccase
Pichia Toolkit: Use of the combinatorial library screening system for expression of a marine laccase
Pnh_Lac1 (Lac1) gene from the marine-derived fungus Peniophora sp. CBMAI 1063 was expressed in Pichia pastoris using the P...
Evaluating for enhancing oil palm growth and biochemical defense against fusarium wilt caused by f. sp.
Evaluating for enhancing oil palm growth and biochemical defense against fusarium wilt caused by f. sp.
This work aimed to evaluate the antagonist effect of Trichoderma viride against Fusarium oxysporum and its ability to prom...
: a multidrug-resistant opportunistic human pathogen — first clinical isolation in the Czech Republic
: a multidrug-resistant opportunistic human pathogen — first clinical isolation in the Czech Republic
The genus Escherichia comprises seven species, including Escherichia marmotae, described in 2015 from the feces of healthy...
Virulence potential of sensu lato group bacteria isolated from green leafy vegetables
Virulence potential of sensu lato group bacteria isolated from green leafy vegetables
In this study, the virulence potential—including hemolytic activity, toxin gene content, and antibiotic resistance p...
Urine-based ELISA for non-invasive diagnosis of urogenital schistosomiasis: a promising tool for resource-limited regions
Urine-based ELISA for non-invasive diagnosis of urogenital schistosomiasis: a promising tool for resource-limited regions
Traditional serological diagnosis can be invasive and uncomfortable, potentially discouraging patients, especially women a...
Structure-based design of PptT-ACP complex inhibitors using derivative design and machine learning
Structure-based design of PptT-ACP complex inhibitors using derivative design and machine learning
Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), remains a critical global health challenge, particularly wi...
Dual-responsive synthetic gene circuit for dynamic biologic drug delivery via inflammatory and circadian signaling pathways
Dual-responsive synthetic gene circuit for dynamic biologic drug delivery via inflammatory and circadian signaling pathways
Engineered cells provide versatile tools for precise, tunable drug delivery, especially when synthetic stimulus-responsive...
Core-shell nanofiber dressings with zinc oxide nanoparticles and cell-free fat extract: boosting fibroblast activity and antibacterial efficacy
Core-shell nanofiber dressings with zinc oxide nanoparticles and cell-free fat extract: boosting fibroblast activity and antibacterial efficacy
This study presents the development and characterization of innovative core-shell nanofiber wound dressings incorporating ...
Enhancing in vitro osteogenic differentiation of mesenchymal stem cells via sustained dexamethasone delivery in 3D-Printed hybrid scaffolds based on polycaprolactone-nanohydroxyapatite/alginate-gelatin for bone regeneration
Enhancing in vitro osteogenic differentiation of mesenchymal stem cells via sustained dexamethasone delivery in 3D-Printed hybrid scaffolds based on polycaprolactone-nanohydroxyapatite/alginate-gelatin for bone regeneration
Layer-by-layer 3D-printing was effectively applied to prepare a biomimetic combined structure composing hard composite (PC...
Bio-engineered thermo-sensitive alginate/PNIA-g-CS co-polymeric injectable hydrogel laden with GDF-5 to stimulate nucleus pulposus for IVD regeneration
Bio-engineered thermo-sensitive alginate/PNIA-g-CS co-polymeric injectable hydrogel laden with GDF-5 to stimulate nucleus pulposus for IVD regeneration
Chronic back pain and disability are primarily caused by intervertebral disc degeneration (IDD) that requires novel therap...
Codon usage modulates the relationship between the burden and yield of protein overexpression
Codon usage modulates the relationship between the burden and yield of protein overexpression
Excess utilization of translational resources is a critical source of burden on cells engineered to overexpress exogenous ...
Characterization of keratinase from Chryseobacterium camelliae Dolsongi-HT1 and efficacy on skin exfoliation
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Enzymatic production of chitooligosaccharides with high degree of polymerisations and their potential application to soy sauce preservation
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