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Metformin mitigates potassium bromate-induced liver grievance in rat through attenuating NF-kB and PI3K/Akt pathway
BackgroundMetformin (MET) is a dietary polyphenolic compound that exhibits anti-inflammatory and antioxidant properties. T...
The evolution of isothermal amplification technology: A bibliometric study (2013–2022)
BackgroundIsothermal amplification is a nucleic acid amplification technology (NAAT) that has contributed significantly to...
Optimizing the process conditions for the biosorption of chromium (VI) by Bacillus subtilis in artificial wastewater
BackgroundThe contamination by heavy metals, particularly hexavalent chromium Cr (VI), is a pressing environmental concern...
Effect of flaxseed’s supplement on AMPKα2′s expression in non-diabetic and diabetic patients having follicular thyroid carcinoma on mitochondrial’s ATP synthase for TPC-1 cell line
BackgroundThis study examined the effects of flaxseed oil supplementation on the expression of adenosine monophosphate-act...
The biological agent rituximab ameliorates DNA damage and repair efficiency in the somatic cells of arthritic mice
BackgroundRheumatoid arthritis (RA) is an autoimmune disorder that deteriorates joints and can affect various physiologica...
Response of heterotrophic nitrifying/aerobic denitrifying strain Pseudomonas stutzeri YXH-102 to hypersaline stress
BackgroundHypersaline wastewater poses significant environmental challenges, necessitating efficient bioremediation strate...
Application of mitochondrial genomes to species identification and evolution
Mitochondrial genomes (mtDNA) have become invaluable in species classification and evolutionary studies due to their uniqu...
Mapping the genomic position of xylanase genes on Bacillus safensis FB03 and optimizing the xylanase fermentation medium by Box-Behnken Design from an unconventional carbon source
BackgroundThe ability of Bacillus safensis to synthesize xylanase and other industrially important enzymes utilizing ligno...
NEDD4L/RHOF axis suppresses the malignant phenotypes and lipid metabolism of breast cancer and NEDD4L is affected by upstream ALKBH5
BackgroundThe protein posttranslational modifications, including ubiquitination and methylation, exhibit the essential fun...
Circulating exosomal miRNA signatures as potential biomarkers and therapeutic targets in biliary colic
BackgroundBiliary colic (BC), characterized by intermittent pain due to gallstone-related bile duct obstruction, remains p...
Chufeng Yisun Decoction treat dry eye syndrome by inhibiting the PI3K/Akt pathway
BackgroundDry eye disease seriously affects people’s work and life. Chufeng Yisun Decoction is a traditional Chinese medic...
Isolation, purification and physicochemical characterization of Cichorium intybus L. root polysaccharide and its protective effect against CCl4-induced liver injury
BackgroundLiver injury is a major cause of hepatic diseases, often leading to impaired liver function. Current treatments ...
Tianma granules: Bridging traditional medicine and modern science to combat colorectal cancer via ferroptosis
BackgroundThis study aims to investigate the ferroptosis-inducing effects of Tianma Granules (TMG) in colorectal cancer an...
Transcriptomic and metabolomic profiling reveals key mechanisms of alkaline stress tolerance in rice
BackgroundAlkaline stress severely restricts rice growth and yield by disrupting ion balance, nutrient uptake, and oxidati...
Fungal community dynamics and pathogenic risk in composting, vermicomposting and leachate systems amended with rabbit manure
BackgroundUnderstanding the dynamics of fungal communities in composting and vermicomposting systems is essential for opti...
Onion peel-mediated biosynthesis of TiO2-ZnO bimetallic nanoparticles: Antimicrobial, antibiofilm, and anticancer activities
BackgroundThe rising challenges of antibiotic resistance and cancer necessitate the development of sustainable, cost-effec...
Improved resistance to basal rot disease and promotion of onion plant growth by Aspergillus terreus-mediated silver nanoparticles
BackgroundOnions, a vital agricultural crop rich in carbohydrates and essential minerals, face severe threats from Fusariu...
Screening of proteolytic, amylolytic, and lipolytic bacteria and their consortia for concomitant production of hydrolytic enzymes and bioremediation of shrimp pond sludge
BackgroundAquaculture has become the fastest-growing sector in recent decades, and this has led to intensified cultural pr...
Unveiling microbial secondary metabolite biosynthetic gene clusters from alkaline soda Lake Chitu, in the Ethiopian Rift Valley
Volume 77, September 2025, Pages 48-58Author links open overlay panel, , , , , , AbstractBackgroundMicroorganisms inhabiti...
Evaluation of high-value bioproducts production by marine endophytic fungus Arthrinium sp. FAKSA 10 under solid state fermentation using agro-industrial wastes
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Antibiotic evaluation of the nanocomposites IONs-MWCNTs-Pc and IONs-GO-Pc encapsulated in the biocompatible hydrogel poly(VCL-co-PEGDA) based on photodynamic effect
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Network pharmacology and experimental verification reveal the mechanism of Qingfei Tongluo mixture in treating pulmonary fibrosis
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Development of a chemically defined medium for Yarrowia yeasts using a strategy of biological mimicry
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Whole-transcriptome analysis reveals the characteristics of intramuscular fat circRNA expression and its associated network in grazing yaks of different months of age under cold stress
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A sustainable exploitation of high-protein feather waste for production of cold-adapted keratinase by Penicillium lanosocoeruleum KSA-55
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circUBAP2 ameliorates hypoxia-induced acute myocardial injury by competing with miR-148b-3p and mediating CDKN1B expression
circUBAP2 ameliorates hypoxia-induced acute myocardial injury by competing with miR-148b-3p and mediating CDKN1B expression
Acute myocardial infarctionCCK-8 assayCDKN1BcircUBAP2Flow cytometryHigh-throughput sequencingInflammationLDH releaseLucife...
Synthesis of hot spring origin bacterial cell wall polysaccharide-based copper nanoparticles with antibacterial property
Synthesis of hot spring origin bacterial cell wall polysaccharide-based copper nanoparticles with antibacterial property
Volume 68, March 2024, Pages 11-19Author links open overlay panel, , , , , AbstractBackgroundAt present, research on facil...
A novel nanoemulsion based on clove and thyme essential oils: Characterization, antibacterial, antibiofilm and anticancer activities
A novel nanoemulsion based on clove and thyme essential oils: Characterization, antibacterial, antibiofilm and anticancer activities
Antibacterial activityAntibiofilm activityAnticancer activityBiofilm inhibitionBiomedical applicationsClove oilDLS (Dynami...
Circular RNA FMN2 motivates colorectal cancer development by mediating tumor-associated macrophage polarization by controlling the microRNA-150-5p/PIK3R3 axis
Circular RNA FMN2 motivates colorectal cancer development by mediating tumor-associated macrophage polarization by controlling the microRNA-150-5p/PIK3R3 axis
circFMN2Circular RNAColorectal cancerM2 macrophage polarizationmicroRNAmiR-150-5Molecular targetTumor microenvironmentTumo...
Successful CRISPR/Cas9-mediated HDR at individual DNA breakpoints using TFO-based targeted template design
Successful CRISPR/Cas9-mediated HDR at individual DNA breakpoints using TFO-based targeted template design
CRISPR-Cas9Donor templateHomologous-Directed Repair (HDR)PolyPurine Reverse Hoogsteen hairpins (PPRHs)Repair templateRepai...
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