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Preoperative treatment and postoperative outcomes in osteoporotic patients with vertebral fractures: a longitudinal database study
Preoperative treatment and postoperative outcomes in osteoporotic patients with vertebral fractures: a longitudinal database study
This study aimed to investigate perioperative treatment and postoperative outcomes in osteoporotic patients with vertebral...
Bone mineral density after spinal cord injury: assessment of hip and knee measurements
Bone mineral density after spinal cord injury: assessment of hip and knee measurements
Bone loss is most common around the knee region in spinal cord injury (SCI) population. However, bone mineral density (BMD...
Three-year trends in early hip fracture surgery surrounding a national reimbursement policy in Japan
Three-year trends in early hip fracture surgery surrounding a national reimbursement policy in Japan
Timely surgical intervention for hip fractures is essential for improving outcomes in older adults. Japan’s Ministry...
Association between serum zinc concentration and fracture risk in postmenopausal women: a 9-year cohort study
Association between serum zinc concentration and fracture risk in postmenopausal women: a 9-year cohort study
The association between serum zinc (SZn) concentration and fracture risk in postmenopausal women was investigated. Women (...
Platelet-like cells differentiated from adipose-derived mesenchymal stem cells inhibit acute inflammation of tendinopathy in rats
Platelet-like cells differentiated from adipose-derived mesenchymal stem cells inhibit acute inflammation of tendinopathy in rats
Tendinopathy, a disease that causes inflammation and pain and limits patients’ activities of daily living, is consid...
One-year bone mineral density gains with anti-osteoporotic medications and clinical factors associated with non-BMD gainers
One-year bone mineral density gains with anti-osteoporotic medications and clinical factors associated with non-BMD gainers
Despite the increasing number of anti-osteoporotic medications for improving bone mineral density (BMD) and reducing fract...
The role of Tmem119 in the estrogen action on bone in mice
The role of Tmem119 in the estrogen action on bone in mice
Postmenopausal osteoporosis is a critical task in the clinical management of older individuals. Numerous studies have prop...
Combining GNRI and CLR index predicts outcome following hip fracture surgery
Combining GNRI and CLR index predicts outcome following hip fracture surgery
Hip fractures in older adults lead to high mortality and reduced quality of life, requiring effective outcome prediction t...
Facial skin aging is a potential osteoporosis-associated marker: evidence from both observational and genetic studies
Facial skin aging is a potential osteoporosis-associated marker: evidence from both observational and genetic studies
Facial skin aging (FSA) is a very easily observable indicator of aging, but whether FSA is associated with osteoporosis is...
Beyond hormones: 3PM approach to vaginal microbiota dynamics in postmenopausal women
Beyond hormones: 3PM approach to vaginal microbiota dynamics in postmenopausal women
Menopause marks a critical transition characterized by ceased ovarian function and declining estrogen levels, affecting mu...
Comprehensive genome-wide analysis of retinal vessel caliber reveals microvascular-blood pressure pathways: advancing predictive, preventive, and personalized medicine
Comprehensive genome-wide analysis of retinal vessel caliber reveals microvascular-blood pressure pathways: advancing predictive, preventive, and personalized medicine
Retinal vessel caliber is strongly associated with systemic blood pressure (BP); however, the causal relationship between ...
Vision transformer-based stratification of pre/diabetic and pre/hypertensive patients from retinal photographs for 3PM applications
Vision transformer-based stratification of pre/diabetic and pre/hypertensive patients from retinal photographs for 3PM applications
Diabetes and hypertension pose significant health risks, especially when poorly managed. Retinal evaluation though fundus ...
The 3PM transformation potential of minimal residual disease in solid tumor management: a bibliometric analysis and review
The 3PM transformation potential of minimal residual disease in solid tumor management: a bibliometric analysis and review
Over the past two decades, significant progress has been made in the study of minimal residual disease (MRD) in patients w...
Systemic inflammation at the oral–ocular interface: a 3P medicine perspective on the relationship between periodontitis and eye diseases
Systemic inflammation at the oral–ocular interface: a 3P medicine perspective on the relationship between periodontitis and eye diseases
Periodontitis is a common source of chronic systemic inflammation, driven by bacterial translocation and cytokine release ...
Advanced 3PM strategies in traditional Chinese medicine gels for wound healing integrating 3D/4D printing, network pharmacology and multiomics technologies
Advanced 3PM strategies in traditional Chinese medicine gels for wound healing integrating 3D/4D printing, network pharmacology and multiomics technologies
This review examines advanced predictive, preventive, and personalized medicine (3PM) strategies, along with the targeted ...
Establishment of reference intervals for serum immunoglobulin G -glycosylation features in healthy Chinese adults: a nationwide survey in the framework of predictive, preventive, and personalized medicine
Establishment of reference intervals for serum immunoglobulin G -glycosylation features in healthy Chinese adults: a nationwide survey in the framework of predictive, preventive, and personalized medicine
Immunoglobulin G (IgG) N-glycosylation plays a vital role in the pathogenesis of autoimmune disorders, inflammatory diseas...
Development of a predictive framework for ovarian reserve decline based on pelvic microbiota dysbiosis
Development of a predictive framework for ovarian reserve decline based on pelvic microbiota dysbiosis
Diminished ovarian reserve (DOR) is increasingly recognized as a multifactorial condition, not solely related to aging. Em...
Creatine as a mitochondrial theranostic in predictive, preventive, and personalized medicine
Creatine as a mitochondrial theranostic in predictive, preventive, and personalized medicine
Creatine, traditionally recognized for its role in skeletal muscle energy metabolism, is increasingly emerging as a mitoch...
Ferroptosis in acinar cells of traumatic pancreatitis: implications for predictive, preventive, and personalized approaches in intra-abdominal infection management
Ferroptosis in acinar cells of traumatic pancreatitis: implications for predictive, preventive, and personalized approaches in intra-abdominal infection management
Traumatic pancreatitis (TP) is a distinct subtype of pancreatitis. Although ferroptosis of pancreatic acinar cells is well...
How to use an extensive Flammer syndrome phenotyping for a holistic protection against health-to-disease transition — facts and practical recommendations
How to use an extensive Flammer syndrome phenotyping for a holistic protection against health-to-disease transition — facts and practical recommendations
Due to their phenotype-associated attitude predominantly oriented towards high performance, Flammer syndrome (FS) phenotyp...
Multivariable data-driven framework of predictive, preventive, and personalized medicine for long-term atrial fibrillation risk in patients with new-onset obstructive sleep apnea
Multivariable data-driven framework of predictive, preventive, and personalized medicine for long-term atrial fibrillation risk in patients with new-onset obstructive sleep apnea
Atrial fibrillation (AF) presents a significant challenge in patients with obstructive sleep apnea (OSA), as traditional r...
Enhancing cardiovascular risk prediction in hypertensive adults: a 3PM-based evaluation of insulin resistance and arterial stiffness
Enhancing cardiovascular risk prediction in hypertensive adults: a 3PM-based evaluation of insulin resistance and arterial stiffness
Hypertension management remains challenging due to coexisting insulin resistance (IR) and arterial stiffness—two sil...
in noncommunicable disease management: therapeutic prospects within the PPPM framework
in noncommunicable disease management: therapeutic prospects within the PPPM framework
Non-communicable diseases (NCDs), including cardiovascular diseases, respiratory disorders, And age-related degenerative d...
Explainable multiomic screening for suboptimal health status in young adults: 3PM-guided innovation is envisaged
Explainable multiomic screening for suboptimal health status in young adults: 3PM-guided innovation is envisaged
Suboptimal health status (SHS) is a reversible predisease stage and represents a key “window of opportunity” f...
The use of predictive, preventive, and personalized medical approaches to optimize hypertension management
The use of predictive, preventive, and personalized medical approaches to optimize hypertension management
Hypertension, a major modifiable risk factor for cardiovascular disease, exhibits significant heterogeneity due to genetic...
Bidirectional associations between kidney function decline and carotid plaque progression: a longitudinal cohort study in the context of predictive, preventive, and personalised medicine
Bidirectional associations between kidney function decline and carotid plaque progression: a longitudinal cohort study in the context of predictive, preventive, and personalised medicine
Atherosclerosis and chronic kidney disease are major contributors to cardiovascular disease (CVD) and premature mortality ...
Glioma angiogenesis phosphoproteome landscape and biomarker sets identified with phenome-centered multiomics toward 3P medical approaches
Glioma angiogenesis phosphoproteome landscape and biomarker sets identified with phenome-centered multiomics toward 3P medical approaches
Protein phosphorylation is an important molecular event in tumor angiogenesis that is a canonical hallmark in glioma. We h...
Multimodal AI-based modeling of glaucoma progression: a 3PM-guided approach integrating structural, functional, and vascular patterns
Multimodal AI-based modeling of glaucoma progression: a 3PM-guided approach integrating structural, functional, and vascular patterns
Glaucoma remains the leading cause of irreversible blindness worldwide. The development of predictive, preventive, and per...
A comprehensive single-cell atlas of three centenarian cohorts unveils unique natural killer cell signatures and enhanced mutual interactions among peripheral immune cells
Volume 120, October 2025, 105922Author links open overlay panel, , , , , , , , , , , , , , , SummaryBackgroundCentenarians...
Fitness costs of mobilised colistin resistance gene 3 (mcr-3): systematic review, epidemiological study, and functional analysis
Volume 120, October 2025, 105923Author links open overlay panel, , , , , , , , , , , , , , , , , , , …SummaryBackgroundThe...
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