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Parosmia: Pathophysiology and Management
Parosmia: Pathophysiology and Management
Parosmia is a qualitative olfactory disorder in which there is a mismatch between the memory of an odor and the actual exp...
The Impact of the Indoor Environment on Childhood Asthma
The Impact of the Indoor Environment on Childhood Asthma
This manuscript reviews the impact of important indoor environmental exposures on pediatric asthma, with a focus on recent...
Hypersensitivity Reactions to Anticonvulsants
Hypersensitivity Reactions to Anticonvulsants
Antiepileptics are the mainstay of treatment for seizure management. Immediate and delayed hypersensitivity reactions asso...
Effect of Dupilumab in CRSwNP Sinonasal Outcomes from Real Life Studies: A Systematic Review with Meta-analysis
Effect of Dupilumab in CRSwNP Sinonasal Outcomes from Real Life Studies: A Systematic Review with Meta-analysis
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a debilitating inflammatory condition that significantly impacts qual...
Burden of Respiratory Syncytial Virus Disease in Adults with Asthma and Chronic Obstructive Pulmonary Disease: A Systematic Literature Review
Burden of Respiratory Syncytial Virus Disease in Adults with Asthma and Chronic Obstructive Pulmonary Disease: A Systematic Literature Review
Accumulating data indicate that asthma and chronic obstructive pulmonary disease (COPD) increase the risk of severe respir...
Hyper IgE Syndrome: Bridging the Gap Between Immunodeficiency, Atopy, and Allergic Diseases
Hyper IgE Syndrome: Bridging the Gap Between Immunodeficiency, Atopy, and Allergic Diseases
It seeks to answer key questions about the molecular and cellular mechanisms underlying Hyper IgE Syndrome (HIES), the gen...
T Cell Exhaustion in Allergic Diseases and Allergen Immunotherapy: A Novel Biomarker?
T Cell Exhaustion in Allergic Diseases and Allergen Immunotherapy: A Novel Biomarker?
This review explores the emerging role of T cell exhaustion in allergic diseases and allergen immunotherapy (AIT). It aims...
Basophil Activation Test for the Improved Diagnosis of Peanut and Tree Nut Allergy
Basophil Activation Test for the Improved Diagnosis of Peanut and Tree Nut Allergy
As an ex-vivo test of allergic effector cell activation, basophil activation testing (BAT) to allergen enables quantificat...
Climate Change and the Future of Allergies and Asthma
Climate Change and the Future of Allergies and Asthma
Climate change affects global temperature, meteorological variables, plant aerobiology, air pollution exposure and a host ...
Managing Chronic Urticaria in Children: An Update
Managing Chronic Urticaria in Children: An Update
To provide an update and new insights into the management of pediatric patients with chronic urticaria. Chronic urticaria ...
Occupational Respiratory Allergy to Flour in the Modern Era
Occupational Respiratory Allergy to Flour in the Modern Era
A comprehensive literature review was conducted in order to identify and summarize recent research on IgE-mediated occupat...
Pediatric Systemic Autoinflammatory Disorders: An Overview
Pediatric Systemic Autoinflammatory Disorders: An Overview
Systemic autoinflammatory disorders (SAIDs) are a group of diseases that are characterized by recurrent or persistent unpr...
Metabolomics in Childhood Asthma – a Promising Tool to Meet Various Clinical Needs
Metabolomics in Childhood Asthma – a Promising Tool to Meet Various Clinical Needs
The aim of our review is to summarize the available literature where metabolomics was used in studies on childhood asthma,...
Respiratory Health Impacts from Natural Disasters and Other Extreme Weather Events: The Role of Environmental Stressors on Asthma and Allergies
Respiratory Health Impacts from Natural Disasters and Other Extreme Weather Events: The Role of Environmental Stressors on Asthma and Allergies
The frequency of natural disasters, other extreme weather events, and downstream emissions of emerging contaminants is inc...
AI-Driven Biomarker Discovery and Personalized Allergy Treatment: Utilizing Machine Learning and NGS
AI-Driven Biomarker Discovery and Personalized Allergy Treatment: Utilizing Machine Learning and NGS
This review explores the transformative potential of artificial intelligence (AI) and next-generation sequencing (NGS) in ...
Emergency Monitoring Following A Diagnosis of Anaphylaxis
Emergency Monitoring Following A Diagnosis of Anaphylaxis
In this review we explore expanding options for monitoring following anaphylaxis in the home or community setting. We revi...
Epigenetic Modifications in Vitiligo
Epigenetic Modifications in Vitiligo
Vitiligo is an autoimmune depigmenting skin disorder and can affect the mental health of the patients. Current research su...
Effectiveness and Safety of Nemolizumab in Patients with Prurigo Nodularis: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Effectiveness and Safety of Nemolizumab in Patients with Prurigo Nodularis: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Prurigo nodularis (PN) is a chronic, severely pruritic condition that markedly impairs quality of life. Existing treatment...
Exploring Gut Microbiota in Systemic Lupus Erythematosus: Insights and Biomarker Discovery Potential
Exploring Gut Microbiota in Systemic Lupus Erythematosus: Insights and Biomarker Discovery Potential
Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease characterized by chronic inflammation and multi-organ d...
Inhalant Mediated Allergy: Immunobiology, Clinical Manifestations and Diagnosis
Inhalant Mediated Allergy: Immunobiology, Clinical Manifestations and Diagnosis
Inhalant allergen–mediated respiratory diseases, including asthma and allergic rhinitis, have become increasing glob...
Targeting IL-13 and IL-4 in Asthma: Therapeutic Implications on Airway Remodeling in Severe Asthma
Targeting IL-13 and IL-4 in Asthma: Therapeutic Implications on Airway Remodeling in Severe Asthma
Asthma is a chronic respiratory disorder affecting individuals across all age groups. It is characterized by airway inflam...
Questionnaire for Clinical Diagnosis of House Dust Mite’s Allergy Approved by Delphi Consensus
Questionnaire for Clinical Diagnosis of House Dust Mite’s Allergy Approved by Delphi Consensus
Despite house dust mite (HDM)-allergy is the most frequent in the world, no standard questionnaire exists to help physicia...
Molecular Diagnosis to IgE-mediated Wheat Allergy and Wheat-Dependent Exercise-Induced Anaphylaxis
Molecular Diagnosis to IgE-mediated Wheat Allergy and Wheat-Dependent Exercise-Induced Anaphylaxis
IgE-mediated wheat allergy is an emerging problem worldwide, particularly prevalent in Northern Europe and parts of Asia. ...
Mechanisms and Therapeutic Implications of EZH2 in Nasal Diseases
Mechanisms and Therapeutic Implications of EZH2 in Nasal Diseases
Enhancer of zeste homolog 2 (EZH2), a protein encoded by the EZH2 gene, is a crucial subunit in polycomb repressive comple...
Neutrophilic Urticarial Dermatosis: A Window into Systemic Inflammation and Autoimmune Disorders
Neutrophilic Urticarial Dermatosis: A Window into Systemic Inflammation and Autoimmune Disorders
Neutrophilic urticarial dermatosis (NUD) is a distinctive dermatological manifestation that is commonly associated with sy...
Atopic Dermatitis: The Relationship Between Immune Mediators and Skin Lipid Barrier
Atopic Dermatitis: The Relationship Between Immune Mediators and Skin Lipid Barrier
Atopic dermatitis (AD) is a chronic inflammatory skin disease that is prevalent worldwide with complex etiology. Skin barr...
Macrophage-Centric Immunometabolic Crosstalk in Alopecia Areata Pathogenesis: Mechanisms and Therapeutic Implications
Macrophage-Centric Immunometabolic Crosstalk in Alopecia Areata Pathogenesis: Mechanisms and Therapeutic Implications
Although alopecia areata (AA) is recognized as a hair loss disorder stemming from the dysregulation of cutaneous immune ho...
Sex Bias in Systemic Sclerosis: from Clinical to Immunological Differences
Sex Bias in Systemic Sclerosis: from Clinical to Immunological Differences
Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by microvasculopathy, extensive fibrosis, and autoa...
Allergic Rhinitis is Associated with Increased Suicidality: A Systematic Review and Meta-Analysis
Allergic Rhinitis is Associated with Increased Suicidality: A Systematic Review and Meta-Analysis
Allergic rhinitis (AR) is a common inflammatory condition affecting millions globally. Emerging evidence suggests a potent...
IL-17-Related Pathways and Myeloid Cell Function are Involved in the Mechanism of Sublingual Immunotherapy with for Seasonal Allergic Rhinitis
IL-17-Related Pathways and Myeloid Cell Function are Involved in the Mechanism of Sublingual Immunotherapy with for Seasonal Allergic Rhinitis
The mechanisms underlying immune tolerance induction during sublingual immunotherapy (SLIT) of seasonal allergic rhinitis ...
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