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Caffeic acid phenethyl ester as a potent adjuvant: augmenting cisplatin’s antitumor activity while mitigating nephrotoxicity in triple-negative breast cancer
Siegel RL, Kratzer TB, Giaquinto AN, Sung H, Jemal A. Cancer statistics, 2025. CA Cancer J Clin. 202...
Therapeutic effects of Mongolian medical warm acupuncture on neuropathic pain via gut microbiota and inflammatory pathway regulation in a chronic constriction injury rat model
Finnerup NB, Kuner R, Jensen TS. Neuropathic pain: From mechanisms to treatment. Physiol Rev. 2021;1...
Effect of barley β-glucan on weight gain prevention and angiotensin-converting enzyme 2 (ACE2) activity in Wistar rats
Patel SR, Hu FB. Short sleep duration and weight gain: a systematic review. Obesity (Silver Spring)....
Hibiscus sabdariffa mitigates hyperlipidemia, cardiac oxidative stress, and inflammatory cytokines in serum and cardiac tissue of adult female Wistar rats with fructose-induced metabolic syndrome
Jha BK, Sherpa ML, Imran M, Mohammed Y, Jha LA, Paudel KR, Jha SK. Progress in Understanding Metabol...
Genetic association of dopamine beta-hydroxylase (DBH) rs72393728 and D-amino acid oxidase activator (DAOA) rs3918342 polymorphisms with bipolar disorder in northeastern Algeria
Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JR...
Molecular evidence of polyandry and polygyny in the mating system of the non-biting midge Chironomus riparius (Diptera: Chironomidae)
Samways MJ. Insects in biodiversity conservation: some perspectives and directives. Biodivers Conser...
Resveratrol alleviates hyperlipidemia, inflammation, and oxidative stress in poloxamer 407-induced hyperlipidemic adult Wistar rats
Pham HN, Ibrahim R, Sainbayar E, Olson A, Singh A, Khanji MY, Lee J, Somers VK, Wenger C, Chahal CAA...
Therapeutic potential of Stypocaulon scoparium extract in antioxidant, antimicrobial, anti-inflammatory, and anticancer applications
Dhargalkar VK, Pereira N. Seaweed: promising plant of the millennium. Sci and Cult. 2005; 71. ...
Ugi Three-Component Coupling Strategy for the Synthesis of Bridged Bicyclic Iminosugars
A novel and catalyst-free approach has been accomplished for the synthesis of bridged bicyclic iminosugars through a Ugi 3...
A green and cascade synthesis of functionalized 2-sec.amino-thiophenes from ketene dithioacetals
We have reported the synthesis of pharmacologically valuable tetrasubstituted 2-aminothiophenes through a multi-component ...
Recent advances in visible-light-driven photocatalytic synthesis of biologically active N-heterocycles
Heterocycles that contain nitrogen are a very significant class of chemicals that are employed extensively in medicinal ch...
Iron Catalysis Enables Mild C–Se Bond Formation via Decarboxylative Selenylation
Selenium-containing compounds are pivotal in bioactive molecules, yet efficient C–Se bond formation is of significant inte...
Phenoxysulfonyl Azide: A New Diazo-transfer Reagent for Metal–Free Conversion of Amines to Azides
Phenoxysulfonyl azide (PSA, 1) was synthesized from 1,1'-sulfonylbis(2-methyl-1H-imidazole) (2) and studied for its di...
Base-Promoted Tandem Synthesis of Nitrogen-Containing Compounds: MN(SiMe₃)₂ as Potential Nitrogen Sources
The metal-silylamides [MN(SiMe₃)₂, M = Li, Na, and K] are widely used Brønsted bases and have become among the most p...
Molybdenum Catalyzed Acceptorless Dehydrogenative Approach for Quinoline Synthesis Using Amino Alcohol
We report here bidentate phosphine-ligand based molybdenum π-allyl complex [Mo(CO)2(η3-C3H5)(DPPE)Cl] (Mo-1; DPPE =) in th...
Synthesis and Evaluation of Naphthoquinone-based Probes for Activity-based Protein Profiling of Oxidoreductases
Activity-based protein profiling (ABPP) has become a highly valuable proteomic technique over the past decades especially ...
Silver-Catalyzed Synthesis of Polyfunctionalized 1,7- and 2,7- Benzonaphthyridine Scaffolds and their Access to Perlolidine Derivatives
A regio- and chemoselective silver-catalyzed one-pot synthesis of benzo[b][1,7]- and benzo[c][2,7]-naphthyridines has been...
Co(III)-catalyzed allylation reaction of 2-alkenylpyridines with 2-vinylaziridines: access to 1,4-dienes
A Cp*(CO)CoI2-catalyzed C–H allylation of 2-alkenylpyridines with 2-vinylaziridines is described. This method provides an ...
Pyreno-1,2,4-Triazines as Multifunctional Luminogenic Click Reagents
Several examples of 1,2,4-triazines that contain a pyrene fragment attached to the C5 position and a carbonyl functional g...
Chimeric enediyne for targeted degradation of tumor-associated protein
Protein-radical-oxidation targeting enediyne chimera (PROTEC) comprising an enediyne warhead and a protein-targeting moiet...
Transition-metal and Photocatalyst-free Oxidative Cleavage of Aryl alkynes with PIDA/Iminoiodinanes in Visible Light
We report a transition-metal and photocatalyst-free method for the oxidative cleavage of aryl alkynes using phenyliodine d...
Tumor-targeted fluorescent probes for the detection of hNQO1 in cancer cells
Fluorescent probes for single analyte might produce 'false-positive' signals because the levels of the biomarkers ...
Synthesis of naphth[2,1-a]azulenes via [8 + 2] cycloaddition of 2Hcyclohepta[b]furan-2-ones, and their reactivity, optical, and structural properties
A concise and efficient synthetic route to naphth[2,1-a]azulenes was developed via [8 + 2] cycloaddition of 2Hcyclohepta[b...
Selective Electrochemical Trifluoromethylation of Arylamide-or Aryl-substituted Pyrrole Derivatives †
A selective electrochemical trifluoromethylation reaction for pyrroles, particularly those containing additional aryl grou...
Alterations in starch, sucrose, and abscisic acid metabolism under drought stress in contrasting genotypes of chickpea
Alterations in starch, sucrose, and abscisic acid metabolism under drought stress in contrasting genotypes of chickpea
Plants respond to water scarcity by modifying transcription and metabolite accumulation; however, mechanisms leading to dr...
Co-chaperones fine-tune the function of heat shock protein 70 (Hsp70), whether to fold, hold, or degrade substrates in ensuring cellular protein homeostasis
Co-chaperones fine-tune the function of heat shock protein 70 (Hsp70), whether to fold, hold, or degrade substrates in ensuring cellular protein homeostasis
The molecular chaperone Hsp70 is a pivotal player in cellular protein quality control due to its wide range of substrates ...
Human adipose-derived stem cell exosomes alleviate human respiratory system-related cells damaged by exposure to SO derivatives
Human adipose-derived stem cell exosomes alleviate human respiratory system-related cells damaged by exposure to SO derivatives
Inhalation burns, especially when combined with thermal burns, can be fatal and significantly increase mortality rate thro...
Identification of components of the kallikrein–kinin system in the spine epithelium of the Atlantic stingray,
Identification of components of the kallikrein–kinin system in the spine epithelium of the Atlantic stingray,
The epithelial sheath covering the stingray spine results in wounds to humans that are characterized by edema, necrosis, e...
Enhanced whole-brain calcium imaging and cell identification in reveal AWC neuronal responses to 2-nonanone
Enhanced whole-brain calcium imaging and cell identification in reveal AWC neuronal responses to 2-nonanone
Whole-brain calcium imaging combined with multicolor cell identification is a revolutionary technique for elucidating stru...
Human papillomavirus vaccine: Success and challenges
Human papillomavirus vaccine: Success and challenges
Persistent infection with high-risk human papillomavirus (HPV) is a major etiological cause of cancers associated with the...
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