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Therapeutic role of hucMSC-sEV-enriched miR-13896 in cisplatin-induced acute kidney injury through M2 macrophage polarization
Therapeutic role of hucMSC-sEV-enriched miR-13896 in cisplatin-induced acute kidney injury through M2 macrophage polarization
Human umbilical cord mesenchymal stem cell-derived small extracellular vesicles (hucMSC-sEV) have recently garnered attent...
Molecular mechanism of ZC3H13 -mediated ferroptosis in doxorubicin resistance of triple negative breast cancer
Molecular mechanism of ZC3H13 -mediated ferroptosis in doxorubicin resistance of triple negative breast cancer
Triple negative breast cancer (TNBC) continues to be the most aggressive subtype of breast cancer that frequently develops...
Glycolysis regulates palatal mesenchyme proliferation through axis via classical and non-classical pathways
Glycolysis regulates palatal mesenchyme proliferation through axis via classical and non-classical pathways
Abnormal embryonic development leads to the formation of cleft palate (CP) which is difficult to be detected by genetic sc...
Neutrophil-derived heparin-binding protein increases endothelial permeability in acute lung injury by promoting TRIM21 and the ubiquitination of P65
Neutrophil-derived heparin-binding protein increases endothelial permeability in acute lung injury by promoting TRIM21 and the ubiquitination of P65
Acute lung injury (ALI), which poses a significant public health threat, is commonly caused by sepsis. ALI is associated w...
The microRNA-mediated apoptotic signaling axis in male reproduction: a possible and targetable culprit in male infertility
The microRNA-mediated apoptotic signaling axis in male reproduction: a possible and targetable culprit in male infertility
Recently, infertility has emerged as a significant and prevalent public health concern warranting considerable attention. ...
Andrographolide ameliorates sepsis-induced acute liver injury by attenuating endoplasmic reticulum stress through the FKBP1A-mediated NOTCH1/AK2 pathway
Andrographolide ameliorates sepsis-induced acute liver injury by attenuating endoplasmic reticulum stress through the FKBP1A-mediated NOTCH1/AK2 pathway
Andrographolide (AP) has been shown to possess anti-inflammatory activities. In this study, the impact of AP in sepsis-ind...
Transcriptomic changes in oxidative stress, immunity, and cancer pathways caused by cannabis vapor on alveolar epithelial cells
Transcriptomic changes in oxidative stress, immunity, and cancer pathways caused by cannabis vapor on alveolar epithelial cells
As legalization of cannabis increases worldwide, vaping cannabis is gaining popularity due to the belief that it is less h...
Targeted nanoparticle delivery system for tumor-associated macrophage reprogramming to enhance TNBC therapy
Targeted nanoparticle delivery system for tumor-associated macrophage reprogramming to enhance TNBC therapy
Triple-negative breast cancer (TNBC) poses as a daunting and intricate manifestation of breast cancer, highlighted by few ...
Exosome-mediated effects of BRCA1 on cardiovascular artery disease
Exosome-mediated effects of BRCA1 on cardiovascular artery disease
The progression of coronary artery disease atherosclerosis (CAD) is closely associated with cardiomyocyte apoptosis and in...
CUL1-neddylation contributes to K29-linked ubiquitination on p27 for autophagic degradation in sorafenib-resistant liver cancer
CUL1-neddylation contributes to K29-linked ubiquitination on p27 for autophagic degradation in sorafenib-resistant liver cancer
Sorafenib has demonstrated great efficacy in liver cancer, however, its application as first-line treatment has been hampe...
Olfactory mucosal mesenchymal stem cell-derived exosome Lnc A2M-AS1 ameliorates oxidative stress by regulating TP53INP1-mediated mitochondrial autophagy through interacting with IGF2BP1 in Parkinson’s diseases
Olfactory mucosal mesenchymal stem cell-derived exosome Lnc A2M-AS1 ameliorates oxidative stress by regulating TP53INP1-mediated mitochondrial autophagy through interacting with IGF2BP1 in Parkinson’s diseases
Exosome Lnc A2M-AS1 from olfactory mucosa mesenchymal stem cells (OM-MSCs) can ameliorate oxidative stress by improving mi...
Myeloid cells are involved in tumor immunity, metastasis and metabolism in tumor microenvironment
Myeloid cells are involved in tumor immunity, metastasis and metabolism in tumor microenvironment
Bone marrow-derived cells in the tumor microenvironment, including macrophages, neutrophils, dendritic cells, myeloid-deri...
Insights into emerging mechanisms of ferroptosis: new regulators for cancer therapeutics
Insights into emerging mechanisms of ferroptosis: new regulators for cancer therapeutics
Ferroptosis is an iron-dependent form of regulated cell death characterized by the accumulation of iron-dependent lipid pe...
Sodium fluoride promotes myopia progression via the activation of the ferroptosis pathway by PIEZO1 and pharmacological targeting PIEZO1 represents an innovative approach for myopia treatment
Sodium fluoride promotes myopia progression via the activation of the ferroptosis pathway by PIEZO1 and pharmacological targeting PIEZO1 represents an innovative approach for myopia treatment
Sodium fluoride-induced ocular damage constitutes a significant public health concern globally; however, the precise molec...
Early endolysosomal dysfunction is a contributing factor to gadolinium-based contrast agent mouse renal proximal tubule epithelial cell injury
Early endolysosomal dysfunction is a contributing factor to gadolinium-based contrast agent mouse renal proximal tubule epithelial cell injury
The prevalence of contrast-enhanced magnetic resonance imaging (MRI) examinations and the absence of safer alternatives to...
Lamin A/C regulates cerebellar granule cell maturation
Lamin A/C regulates cerebellar granule cell maturation
Lamin A/C is a nuclear type V intermediate filament protein part of the meshwork structure underlying the inner nuclear me...
Targeting B4GALT3 in BMSCs-EVs for Therapeutic Control of HCC via NF-κB pathway inhibition
Targeting B4GALT3 in BMSCs-EVs for Therapeutic Control of HCC via NF-κB pathway inhibition
Examining the communications in the tumor microenvironment (TME) specific to hepatocellular carcinoma (HCC), this explorat...
Dysregulation of the circ-Hdac4/miR-30c/RBPJ axis in decidua impairs placental function in preeclampsia
Dysregulation of the circ-Hdac4/miR-30c/RBPJ axis in decidua impairs placental function in preeclampsia
Embryo implantation relies on complex mother-fetus interactions. Abnormal decidualization can cause various pregnancy comp...
Based exploration of the diagnostic value of oxidative stress-related key genes in chronic obstructive pulmonary disease
Based exploration of the diagnostic value of oxidative stress-related key genes in chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD) ranks as the third most common contributor to global mortality. Oxidative str...
Effect of the MIAT/microRNA 130a-3p/Pdgfra axis on retinal microglia activation in mice with chronic retinal hypoperfusion injury
Effect of the MIAT/microRNA 130a-3p/Pdgfra axis on retinal microglia activation in mice with chronic retinal hypoperfusion injury
This paper aimed to address the function of the MIAT/miR-130a-3p/Pdgfra axis in retinal microglia activation in chronic re...
Racial and ethnic differences in prenatal exposure to environmental phenols and parabens in the ECHO Cohort
Racial and ethnic differences in prenatal exposure to environmental phenols and parabens in the ECHO Cohort
Research suggests racial/ethnic disparities in prenatal exposure to endocrine disrupting environmental phenols (EPs) in li...
Young infants’ exposure to parabens: lotion use as a potential source of exposure
Young infants’ exposure to parabens: lotion use as a potential source of exposure
Parabens are widely used as antimicrobials in personal care products and pharmaceuticals. While previous studies demonstra...
Evaluating personal care product use by Environmental Working Group hazard scores in relation to consumers’ sociodemographic characteristics, purchasing behaviors, and product safety perceptions
Evaluating personal care product use by Environmental Working Group hazard scores in relation to consumers’ sociodemographic characteristics, purchasing behaviors, and product safety perceptions
Personal care products (PCPs) are a source of environmental chemical exposures. Little research has examined the specific ...
Evaluating the environmental justice dimensions of odor in Denver, Colorado
Evaluating the environmental justice dimensions of odor in Denver, Colorado
Odors are a documented environmental justice challenge in Denver, Colorado. Complaints are an important modality through w...
Correction: Noise: a public health problem
Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obta...
Air, surface, and wastewater surveillance of SARS-CoV-2; a multimodal evaluation of COVID-19 detection in a built environment
Air, surface, and wastewater surveillance of SARS-CoV-2; a multimodal evaluation of COVID-19 detection in a built environment
Environmental surveillance of infectious organisms holds tremendous promise to reduce human-to-human transmission in indoo...
Childhood Pb-induced cognitive dysfunction: structural equation modeling of hot and cold executive functions
Childhood Pb-induced cognitive dysfunction: structural equation modeling of hot and cold executive functions
Childhood lead [Pb] exposure has been consistently linked to neurotoxic effects related to the prefrontal cortex, a critic...
Olive oil and castor oil-based self-nanoemulsifying drug delivery system of flurbiprofen can relieve peripheral pain and inflammation through reduction of oxidative stress and inflammatory biomarkers: a comprehensive formulation and pharmacological insights
Olive oil and castor oil-based self-nanoemulsifying drug delivery system of flurbiprofen can relieve peripheral pain and inflammation through reduction of oxidative stress and inflammatory biomarkers: a comprehensive formulation and pharmacological insights
Flurbiprofen (FBP) is poorly water-soluble BCS class II drug with anti-inflammatory and analgesic effects, used to treat a...
Methotrexate for osteoarthritis: a systematic review meta-analysis of randomized controlled trials
Methotrexate for osteoarthritis: a systematic review meta-analysis of randomized controlled trials
Osteoarthritis (OA) is a common joint disorder causing pain and stiffness, with limited effective treatment options. Metho...
A randomized clinical study to evaluate the possible antifibrotic effect of zinc sulfate in chronic HCV patient receiving direct-acting anti-viral therapy
A randomized clinical study to evaluate the possible antifibrotic effect of zinc sulfate in chronic HCV patient receiving direct-acting anti-viral therapy
This study aimed to assess the potential antifibrotic impact of zinc sulfate in chronic Hepatitis C Virus (HCV) patients r...
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