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Olive oil and castor oil-based self-nanoemulsifying drug delivery system of flurbiprofen can relieve peripheral pain and inflammation through reduction of oxidative stress and inflammatory biomarkers: a comprehensive formulation and pharmacological insights

Flurbiprofen (FBP) is poorly water-soluble BCS class II drug with anti-inflammatory and analgesic effects, used to treat a...

Inflammopharmacology

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Methotrexate for osteoarthritis: a systematic review meta-analysis of randomized controlled trials

Osteoarthritis (OA) is a common joint disorder causing pain and stiffness, with limited effective treatment options. Metho...

Inflammopharmacology

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A randomized clinical study to evaluate the possible antifibrotic effect of zinc sulfate in chronic HCV patient receiving direct-acting anti-viral therapy

This study aimed to assess the potential antifibrotic impact of zinc sulfate in chronic Hepatitis C Virus (HCV) patients r...

Inflammopharmacology

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Exploration of molecular interactions responsible for anti-inflammatory attributes of GI friendly micro-sized formulation of flurbiprofen and clove oil

Clove oil obtained from Syzygium aromaticum (L.) is traditionally employed to treat inflammation associated with ...

Inflammopharmacology

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Stimulation, regulation, and inflammaging interventions of natural compounds on nuclear factor kappa B (NF-kB) pathway: a comprehensive review

Nuclear factor kappa B (NF-kB) is a kind of transcription factor which resides in cytoplasm of each cell and on activation...

Inflammopharmacology

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Therapeutic applications of eucalyptus essential oils

Eucalyptus essential oils (EEOs) have gained significant attention recently anticipated to their broad range of prospectiv...

Inflammopharmacology

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Unraveling the hormonal approaches for the treatment of rheumatoid arthritis and its complementary interventions

Rheumatoid Arthritis (RA) is an autoimmune, chronic, systemic inflammatory disease that causes redness, swelling, stiffnes...

Inflammopharmacology

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Advancements in nose-to-brain drug targeting for Alzheimer’s disease: a review of nanocarriers and clinical insights

Alzheimer’s disease (AD) is a type of neurodegenerative disease that describes cognitive decline and memory loss res...

Inflammopharmacology

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Impacts of supplementation with milk proteins on inflammation: a systematic review and meta-analysis

Impacts of milk proteins (MPs) on inflammation are uncertain. The current systematic review and dose–response meta-a...

Inflammopharmacology

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Effect of intramuscular vs intra-articular betamethasone injection on pain and inflammatory factors among patients with severe traumatic knee osteoarthritis

The aim of this study was to comprehensively investigate the clinical efficacy of intraoperative local joint injection and...

Inflammopharmacology

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Targeting the NLRP3 inflammasome as a novel therapeutic target for osteoarthritis

Osteoarthritis, the most common arthritic condition, is an age-related progressive disease characterized by the l...

Inflammopharmacology

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Connecting dots: Preclinical foundations to clinical realities of PDE4 inhibitors in Alzheimer's disease

Alzheimer's Disease (AD), a progressive and age-associated neurodegenerative disorder, is primarily characterized by a...

Inflammopharmacology

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Casticin reduces rosacea-related inflammation by inhibiting mast cell activation via Mas-related G protein-coupled receptor X2

Rosacea is a chronic inflammatory disease characterized by persistent erythema, papules, and pustules, mainly on the skin ...

Inflammopharmacology

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The neuroprotective role of volatile oils: insights into chemical profiles, characteristics, neurochemical mechanisms, and preclinical studies in Alzheimer's disease

Volatile oils (VOs), synonymously termed essential oils (EOs), are highly hydrophobic liquids obtained from aromatic plant...

Inflammopharmacology

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Neuroprotective effects of phytochemicals through autophagy modulation in ischemic stroke

Stroke is a serious life-threatening medical condition. Understanding the underlying molecular mechanisms of this conditio...

Inflammopharmacology

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Uncovering the intricacies of IGF-1 in Alzheimer’s disease: new insights from regulation to therapeutic targeting

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by the accumulation of amyloid-&#...

Inflammopharmacology

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Atopic dermatitis: a comprehensive updated review of this intriguing disease with futuristic insights

Atopic dermatitis (AD) is a paradigmatic prevalent, long-lasting, and inflammatory skin condition with a diverse range of ...

Inflammopharmacology

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PrimPol-mediated repriming elicits gap-filling by template switching and promotes cellular tolerance to cidofovir