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Collection of multimedia measurements to evaluate PFAS human exposure sources in the residential environment
Collection of multimedia measurements to evaluate PFAS human exposure sources in the residential environment
Per- and polyfluoroalkyl substances (PFAS) are anthropogenic chemicals with unique properties and functionality that enabl...
Long-term exposure to air pollution and metabolites in children and young adults in a Swedish birth cohort
Long-term exposure to air pollution and metabolites in children and young adults in a Swedish birth cohort
The biochemical dysregulation underlying the adverse health effects of exposure to air pollution (AP) remains unclear. The...
Infection risk assessment for socially structured population using stochastic microexposure model
Infection risk assessment for socially structured population using stochastic microexposure model
Predicting infection outbreak dynamics within local microenvironments is a challenging task. Some methods assume smaller p...
Timing of puberty in girls and serum polycyclic aromatic hydrocarbon (PAH)-albumin adduct levels: the California PAH Study
Timing of puberty in girls and serum polycyclic aromatic hydrocarbon (PAH)-albumin adduct levels: the California PAH Study
Exposure to environmental chemicals such as polycyclic aromatic hydrocarbons (PAH) may play a role in recent trends of ear...
Occupational heat exposure incidence and sociodemographic disparities for outdoor workers in the United States, 2010–2019
Occupational heat exposure incidence and sociodemographic disparities for outdoor workers in the United States, 2010–2019
Outdoor workers are at high risk of hazardous heat exposures and associated adverse health outcomes. Questions remain as t...
Exposures to combustion sources near military operations in Iraq and Afghanistan using satellite observations
Exposures to combustion sources near military operations in Iraq and Afghanistan using satellite observations
U.S. military personnel deployed to Afghanistan and Iraq were stationed on bases impacted by airborne hazards including em...
Development and evaluation of a computer vision algorithm for quantification of children’s microactivities
Development and evaluation of a computer vision algorithm for quantification of children’s microactivities
Estimates of microactivity (e.g., hand- and object-to-mouth contact) frequencies are essential for modeling children’...
Neurobehavioral performance of dual exposure to organophosphate pesticides and PAHs among farmers in rural agriculture communities
Neurobehavioral performance of dual exposure to organophosphate pesticides and PAHs among farmers in rural agriculture communities
Farmers in Northern Thailand are chronically exposed to organophosphate pesticides (OPs) through agricultural activities a...
Antinociceptive, anti-inflammatory, and antiophidic potential of leaves extract and fraction: an in vitro and in vivo evaluation
Antinociceptive, anti-inflammatory, and antiophidic potential of leaves extract and fraction: an in vitro and in vivo evaluation
Punica granatum (Punicaceae) is a shrub with a worldwide distribution that has been used in folk medicine for the treatmen...
Anti-inflammatory effects of Calebin A on metabolic syndrome via NF-κB signaling pathway modulation
Anti-inflammatory effects of Calebin A on metabolic syndrome via NF-κB signaling pathway modulation
Metabolic syndrome is a complex disorder characterized by a combination of events such as insulin resistance, obesity, dys...
The hydroalcoholic extract of the leaves of red mombin ( L.) is more effective in accelerating ulcer healing than preventing them in rodents
The hydroalcoholic extract of the leaves of red mombin ( L.) is more effective in accelerating ulcer healing than preventing them in rodents
This study evaluated the anti-ulcer effects of the hydroalcoholic extract from the leaves of Spondias purpurea L. (SPHE). ...
Potentiation of analgesic activity following the complexation of Sobral, Faria & Proença () leaf essential oil with β-cyclodextrin
Potentiation of analgesic activity following the complexation of Sobral, Faria & Proença () leaf essential oil with β-cyclodextrin
Pain is a fundamental biological process; however, its acute manifestation may result in dysregulation and tissue injury. ...
Dexketoprofen enhances NLRP3 activation via ATPase activity after canonical stimuli
Dexketoprofen enhances NLRP3 activation via ATPase activity after canonical stimuli
Inflammasomes are crucial elements of the innate immune system, responsible for triggering inflammation through the activa...
Targeting mGluR7 in Parkinson’s disease: a novel approach to neuroprotection and synaptic therapies
Targeting mGluR7 in Parkinson’s disease: a novel approach to neuroprotection and synaptic therapies
Parkinson’s disease (PD) is a progressive neurodegenerative disease characterized by dopaminergic neuronal loss in t...
Beyond the blood–brain barrier: unraveling T cell subsets in CNS immunity and disease
Beyond the blood–brain barrier: unraveling T cell subsets in CNS immunity and disease
The complicated interplay between the central nervous system (CNS) and immune system is critical for both neuroprotection ...
Gastroprotective effect of nifuroxazide against indomethacin-induced gastric ulcers in rats via modulation of Nrf2/HO-1, HMGB1/TLR4/NF-κB p65, and apoptotic caspase-3 signaling pathways
Gastroprotective effect of nifuroxazide against indomethacin-induced gastric ulcers in rats via modulation of Nrf2/HO-1, HMGB1/TLR4/NF-κB p65, and apoptotic caspase-3 signaling pathways
Gastric ulcer (GU) is a common gastrointestinal disease linked to the consumption of non-steroidal anti-inflammatory drugs...
Aspirin’s effect on macrophages beyond its chemopreventive role in inflammation and cancer
Aspirin’s effect on macrophages beyond its chemopreventive role in inflammation and cancer
Aspirin's antineoplastic activities are primarily executed by irreversibly prohibiting COX-1 in platelets, hindering p...
Ozone therapy and the role of the glutathione pathway
Ozone therapy and the role of the glutathione pathway
Oxygen-ozone therapy (OOT) represents a multi-target intervention that engages redox modulation, endothelial repair, nitri...
Targeting the cytokine–redox axis: dose-dependent immunomodulation by methotrexate in a biomarker-guided ovine endotoxaemia model
Targeting the cytokine–redox axis: dose-dependent immunomodulation by methotrexate in a biomarker-guided ovine endotoxaemia model
Oxidative stress and excessive inflammation are central to the pathophysiology of sepsis and its large-animal analogue, en...
Unveiling the secret of cellular metamorphosis: the crucial role of EndMT mechanisms in COVID-19-induced pulmonary fibrosis
Unveiling the secret of cellular metamorphosis: the crucial role of EndMT mechanisms in COVID-19-induced pulmonary fibrosis
The COVID-19 pandemic has resulted in several long-term complications, with COVID-19-induced pulmonary fibrosis being a si...
L. essential oil attenuates inflammation and pain via TRPV1
L. essential oil attenuates inflammation and pain via TRPV1
Pain and inflammation are complex physiological responses. The drugs that are available in the market have multiple side e...
Synthetic cytotoxicity profiling of cohesin mutants highlights recombination-based dependencies
Cohesin maintains genome integrity through its ability to bind and link DNA molecules via a Structural Maintenance of Chro...
Transcription-coupled repair of crosslinking DNA damage
Impediments to faithful transcription must be resolved to ensure accurate gene expression and safeguard normal cellular fu...
"Yin-Yang" of PARP1 in genotoxic and inflammatory response
The poly(ADP-ribose) polymerase superfamily (PARP superfamily) comprises a group of enzymes with ADP-ribosyltransferase (A...
Unveiling cGAS mechanisms: Insights into DNA damage and immune sensing in cancer
The innate immune sensing system plays a critical role in recognizing and responding to DNA damage, which is a key factor ...
DNA repair at the crossroads of tumor immunogenicity and cancer therapy: Harnessing innate and adaptive immune pathways for improved therapeutic outcomes
Immunotherapy has revolutionized cancer treatment, particularly with immune checkpoint inhibitors (ICIs), which harness th...
Harnessing R-loop dynamics: Challenging cancer therapy resistance
RNA:DNA hybrids are atypical nucleic acid structures that predominantly form during the transcription of RNA, resulting in...
FBH1 and the replication stress response: Implications for genome stability and cancer development
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2025 Elsevier B.V., its licensors, an...
Base excision repair in human cancer: Emerging diagnostic and therapeutic target
BER is a highly conserved and major DNA repair mechanism [1], [2] which acts like an immune surveillance system for DNA, e...
From cooperation to conflicts – A complicated relationship between transcription and replication
Volume 152, August 2025, 103872Author links open overlay panel, Highlights•Transcription and DNA replication share the DNA...
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