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White Matter Hyperintensities Contribute to Early Cortical Thinning in Addition to Tau in Aging
Available online 9 July 2025Author links open overlay panel, , Highlights•WMH yield early cortical thinning in AD beyond w...
Comparison of CSF neurofilament light chain and total tau as neurodegeneration markers: associations with synaptic markers and cognitive outcomes
Clinically, Alzheimer`s disease (AD) is a progressive, neurodegenerative disease leading to neurodegeneration and subseque...
Effects of age on the strategic control of recollected content as reflected by modulation of neural correlates of scene retrieval
Neuroimaging studies have often implicated encoding processes in age-related episodic memory decline (see Maillet and Raja...
How is self-reported sleep-disordered breathing linked with biomarkers of Alzheimer’s disease?
The ADNI is a multisite initiative to prevent and treat AD. The MRI and CSF biomarkers, as well as the clinical data used ...
Explaining tip-of-the-tongue experiences in older adults: The role of brain-based and cardiorespiratory fitness factors
Cognitive decline associated with healthy ageing is multifactorial: brain-based and lifestyle factors uniquely and jointly...
Age-related differences in cerebral morphology and microstructure in rhesus macaques
Volume 154, October 2025, Pages 37-46Author links open overlay panel, , , , , Highlights•Age-related morphometric differen...
Two-year changes in hippocampal subfield volumes are age-dependent across the lifespan
The hippocampus (Hc) is a heterogeneous structure composed of cytoarchitectonically distinct regions (subfields): dentate ...
Balance training improves postural control and performance-related prefrontal brain activation in healthy older adults: Results of a six-month randomized controlled training intervention
Age-related deterioration in postural control is an important factor decreasing quality of life. Functional neuroimaging s...
Identifying lifestyle risk factors that discriminate memory trajectories: Differential findings across racial and ethnic groups in older adults
Volume 154, October 2025, Pages 84-91Author links open overlay panel, , , , , , , , , Highlights•Three latent classes of m...
Evaluating the link between hearing loss and Alzheimer’s disease neuropathology: A systematic review and meta-analysis
Hearing loss has been linked with cognitive decline and increased dementia risk. The neurobiological mechanisms underlying...
Neurobiological effects of exergame interventions in older adults with or without a neurocognitive disorder: A systematic review
Volume 154, October 2025, Pages 47-61Author links open overlay panel, , , , , Highlights•Exergames (EG) changed brain stru...
Serum HDL-cholesterol is associated with the clinical-biological profile of early-stage Parkinson’s disease patients independently of APOE
Emerging evidence highlights a possible interplay between serum lipid profiles and Parkinson’s disease (PD), but the biolo...
Epigenetic age is associated with regional brain aging along the sensorimotor-to-association axis of cortical organization
Volume 155, November 2025, Pages 8-12Author links open overlay panel, , , , , , , , , Highlights•Epigenetic age is related...
Associations of IGF-1 and IGFBP-3 with Aging and the Development of Age-Associated Diseases
Associations of IGF-1 and IGFBP-3 with Aging and the Development of Age-Associated Diseases
Aging is a complex biological process that impacts various systems of the body with changes occurring at molecular, cellul...
Artificial Intelligence in Gerontology: Data-Driven Health Management and Precision Medicine
Artificial Intelligence in Gerontology: Data-Driven Health Management and Precision Medicine
As the global population ages, healthcare systems face increasing challenges in managing the complex health needs of older...
On the Role of Sleep in the Aging Processes
On the Role of Sleep in the Aging Processes
Sleep, as a fundamental requirement for the body’s well-being, plays a crucial role in various essential biological ...
Social Virtual Reality as a Solution for Aging Services and Gerontology: Understanding the Older Adults’ Acceptance of Virtual Reality Applications
Social Virtual Reality as a Solution for Aging Services and Gerontology: Understanding the Older Adults’ Acceptance of Virtual Reality Applications
A demographic shift towards an ageing population necessitates a comprehensive examination of the quality of life of the ol...
Elevating Skeletal Muscle GLUT4 Abundance Does Not Result in a Calorie Restriction-Induced Elevation in Insulin-Stimulated Glucose Uptake by Skeletal Muscle from Female AS160-Knockout Rats
Elevating Skeletal Muscle GLUT4 Abundance Does Not Result in a Calorie Restriction-Induced Elevation in Insulin-Stimulated Glucose Uptake by Skeletal Muscle from Female AS160-Knockout Rats
Calorie restriction (CR: ∼20–40% below AL: ad libitum intake) can increase insulin sensitivity in various spec...
Interaction between Body Mass Index and Depressive Symptoms in Older Adults: Evidence from a Large-Scale Population-Based Cohort Study
Interaction between Body Mass Index and Depressive Symptoms in Older Adults: Evidence from a Large-Scale Population-Based Cohort Study
There are mixed results on the correlation between body mass index and depressive symptoms among older adults. This observ...
Evaluation of the Psychometric Properties of the Turkish Form of the Will-to-Live Scale in Older Adults
Evaluation of the Psychometric Properties of the Turkish Form of the Will-to-Live Scale in Older Adults
The Will-to-Live (WTL) scale measures desire for life and life commitment across populations. However, psychometric eviden...
Burden of Carbon Monoxide Poisoning in Asian Countries From 1990 to 2021 and Its Projection Until 2030: An Analysis of the Global Burden of Disease Study 2021
Burden of Carbon Monoxide Poisoning in Asian Countries From 1990 to 2021 and Its Projection Until 2030: An Analysis of the Global Burden of Disease Study 2021
Assessing the burden of CO poisoning in Asia from 1990 to 2021 utilizing data from the Global Burden of Disease Study (GBD...
Mental Disorders in Danish Hospital Registers: A Review of Content and Possibilities for Epidemiological Research
Mental Disorders in Danish Hospital Registers: A Review of Content and Possibilities for Epidemiological Research
Overview of the available data for investigating mental disorders in the Danish hospital registers.
Statin Therapy in Early Breast Cancer: The MASTER Trial; A Randomized Phase III, Placebo-Controlled Comparison of Standard (Neo)Adjuvant Therapy Plus Atorvastatin versus Standard (Neo)Adjuvant Therapy Plus Placebo
Statin Therapy in Early Breast Cancer: The MASTER Trial; A Randomized Phase III, Placebo-Controlled Comparison of Standard (Neo)Adjuvant Therapy Plus Atorvastatin versus Standard (Neo)Adjuvant Therapy Plus Placebo
Clinical trial testing the efficacy of statin exposure on early estrogen receptor-positive (ER+) breast cancer and candida...
Effect of SGLT2 Inhibitors on Diabetes Progression in Statin-Treated Patients: A Population-Based Cohort Study
Effect of SGLT2 Inhibitors on Diabetes Progression in Statin-Treated Patients: A Population-Based Cohort Study
This study evaluates whether the use of SGLT2 as the second-line therapy can attenuate diabetes progression among patients...
High Validity and Completeness of the Septoplasty Surgical Procedure Code in the Danish National Patient Registry
High Validity and Completeness of the Septoplasty Surgical Procedure Code in the Danish National Patient Registry
Assessing the validity and completeness of the septoplasty surgical procedure code in the Danish National Patient Registry.
Self-Selection Bias in Randomized and Observational Studies on Screening Mammography: A Quantitative Assessment
Self-Selection Bias in Randomized and Observational Studies on Screening Mammography: A Quantitative Assessment
Quantifying how much of the changes in the risk of breast cancer death reported by observational studies on mammography sc...
Impact of New-Onset Atrial Fibrillation on Mortality in Critically Ill Patients [Letter]
Impact of New-Onset Atrial Fibrillation on Mortality in Critically Ill Patients [Letter]
Letter for the article Impact of New-Onset Atrial Fibrillation on Mortality in Critically Ill Patients
Global Burden of Kidney Cancer Attributable to High Body Mass Index in Adults Aged 60 and Older from 1990 to 2021 and Projections to 2040: A Systematic Analysis for the Global Burden of Disease Study
Global Burden of Kidney Cancer Attributable to High Body Mass Index in Adults Aged 60 and Older from 1990 to 2021 and Projections to 2040: A Systematic Analysis for the Global Burden of Disease Study
We aim to leverage data from GBD 2021 to conduct an in-depth analysis of the global burden of kidney cancer among individu...
Celiac Disease and Incident Dupuytren’s Contracture: A Matched Nationwide Cohort Analysis
Celiac Disease and Incident Dupuytren’s Contracture: A Matched Nationwide Cohort Analysis
Exploring association between celiac disease and Dupuytren’s contracture using data from the Swedish ESPRESSO cohort.
Cohort Profile: The Danish Venous Thromboembolism Cohort – A Linkage Between Danish National Health Surveys and Health Registers
Cohort Profile: The Danish Venous Thromboembolism Cohort – A Linkage Between Danish National Health Surveys and Health Registers
Cohort Profile: The Danish Venous Thromboembolism Cohort – A Linkage Between Danish National Health Surveys and ...
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