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SCI Abstract
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Muscle Strength Matters Most for Risk of Falling Apart from Body Mass Index in Older Adults: A Mediated-Moderation Analysis
The primary objective of this study was to analyze the moderating effect of body mass index (BMI) on the association betwe...
Journal Of Frailty & Aging
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The Relationship between Leisure Time Physical Activity and Cognitive Function in Older Americans
This study aims to investigate the correlation between leisure-time physical activity (LTPA) and cognitive function in old...
Journal Of Frailty & Aging
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Exploring the Role of Antibiotics in Hospice Care
The decision regarding the use of antibiotics in hospice care, whether to initiate, defer, or discontinue therapy, present...
Journal Of Frailty & Aging
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Comparative Analysis of Gait Speed Measurement Protocols: Static Start Versus Dynamic Start in a Cross-Sectional Study Using Light Detection and Ranging
There is currently no standardized protocol for the measurement of gait speed in older adults, particularly regarding the ...
Journal Of Frailty & Aging
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Fecal Microbiota Transplantation Modulates Gut Microbiome Composition and Glial Signaling in Brain and Colon of Rats with Neuropathic Pain: Evidence for Microbiota-Gut-Brain Axis
Despite evidence linking the gut microbiome to neuropathic pain (NP), it is not known if altering gut microbiota can allev...
Journal Of Frailty & Aging
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The Saliva and Muscle Study (SaMu): Rationale and Protocol for Associations between Salivary Microbiome and Accelerated Muscle Ageing
The gut microbiome is recognized as a pivotal factor in the pathophysiology of sarcopenia—a condition marked by the ...
Journal Of Frailty & Aging
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Utilisation and Outcome of Cranial CT Imaging in Older Adults Attending ED Following a Fall
Healthcare demand from falls in older adults is increasing, but guidance from the literature is lacking on the value of ne...
Journal Of Frailty & Aging
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Objective Measures of Physical Activity and Frailty in Ambulatory Adults Aged 85–89 Years in Kawasaki, Japan: A Cross-sectional Study
While physical activity (PA) can reduce physical frailty, the specific intensity and duration of PA required to prevent fr...
Journal Of Frailty & Aging
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Frailty Index, Not Age, Predicts Treatment Outcomes and Adverse Events for Older Adults with Cancer
Frailty is an indicator of individual vulnerability and differentiates health status among people of the same chronologica...
Journal Of Frailty & Aging
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Five-Time Sit-To-Stand Lower Limb Muscle Power in Older Women: An Explorative, Descriptive and Comparative Analysis
Muscle power assessment entails the use of complex equipment which impacts its clinical applicability. Recently, equations...
Journal Of Frailty & Aging
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The Efficacy of 12-Week Progressive Home-Based Strength and Tai-Chi Exercise Snacking in Older Adults: A Mixed-Method Exploratory Randomised Control Trial
Maintaining physical function is important for independence and frailty prevention in later life, but very few older adult...
Journal Of Frailty & Aging
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Exercise Modalities in Multi-Component Interventions for Older adults with Multi-Morbidity: A Systematic Review and Narrative Synthesis
Exercise is efficacious in older adults, including those with multi-morbidity. However, the optimum mode is not known and ...
Journal Of Frailty & Aging
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Application of a Social Vulnerability Index and Its Associations with Physical Frailty and Disability in a Cross-sectional Study of Older Kenyan Women Living with and without HIV
Social vulnerability reflects deficits in social resources that may disproportionally impact older women with HIV (WWH) in...
Journal Of Frailty & Aging
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Polyphenol Supplementation and Sarcopenia: A Systematic Review and Meta-Analysis of Clinical Trials
Experimental evidence suggests that polyphenols, a large group of phytochemicals found in fruits and vegetables, may prese...
Journal Of Frailty & Aging
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Association of Finger Tapping Movements with Frailty Status in older Japanese Adults: A Cross-Sectional Study
Finger tapping impairment and frailty share overlapping pathophysiology and symptoms in older adults, however, the relatio...
Journal Of Frailty & Aging
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Prognostic Value of a Laboratory Index of Frailty in Older Patients Hospitalized for COVID-19: The COMEPA Study
Several indexes based on clinical and laboratory tests to identify frailty and to predict mortality have been produced. On...
Journal Of Frailty & Aging
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Intrinsic Capacity and Its Biological Basis: A Scoping Review
In 2015, the World Health Organization (WHO) introduced the concept of intrinsic capacity (IC) to define healthy aging bas...
Journal Of Frailty & Aging
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Food Insecurity, Vision Impairment, and Longitudinal Risk of Frailty and Falls in The National Health and Aging Trends Study
Both food insecurity (FI) and vision impairment (VI), which are linked, have been independently associated with frailty an...
Journal Of Frailty & Aging
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Impact of Frailty on Gait Speed Improvements in Home Health after Hospital Discharge: Secondary Analysis of Two Randomized Controlled Trials
More than half of older adults are frail or prefrail in the United States, and hospital-associated deconditioning likely i...
Journal Of Frailty & Aging
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Body composition, Falls, and Freezing of Gait in Parkinson’s Disease: Gender-Specific Effects
Postural instability and gait difficulties (PIGD) are a significant cause of mobility loss and lower quality of life in Pa...
Journal Of Frailty & Aging
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The Prevalence of Frailty and Associated Factors, Including Food Security in Community Dwelling Older Adults with Multimorbidity: A Cross-Sectional Analysis from the Longitudinal Aging Study in India
The global increase in multimorbidity among older adults is a result of ongoing epidemiological and demographic transition...
Journal Of Frailty & Aging
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Circulating Angiogenic and Senescent T Lymphocytes in Ageing and Frailty
There is a need to identify vascular and geroscience-relevant markers and mediators that can physiologically link ageing t...
Journal Of Frailty & Aging
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Integrated Service Delivery Model in Primary Care to Improve Frailty in Older Malaysians: GeKo Integrated Service Delivery
This study aimed to evaluate the implementation stage of Malaysia’s GeKo-Integrated Service Delivery (ISD) model for...
Journal Of Frailty & Aging
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Characterizing Deficit Accumulation Among Gulf War Era Veterans
Veterans of the first Gulf War (1990–1991) are reaching middle and older adulthood in differing degrees of health an...
Journal Of Frailty & Aging
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Analysis of the Correspondence of the Degree of Fragility with the Way to Exercise the Force of the Hand
Frailty is a geriatric syndrome characterized by increased individual vulnerability with an increase in both dependence an...
Journal Of Frailty & Aging
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Most Hospital-Acquired Complications among Older Adults Are Associated with Frailty: The South-Western Sydney Frailty and Hospital-Acquired Complications Study
People live longer, and frailty has become an important problem in the acute hospital setting. Increasingly the associatio...
Journal Of Frailty & Aging
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Admission of Older Patients to Geriatric Inpatient Care from the Emergency Department Compared with Admission through Acute Medical Unit: Cost and Length of Stay Outcomes
To investigate whether direct admission to geriatric inpatient care from the emergency department (EMD) was associated wit...
Journal Of Frailty & Aging
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Blood Pressure Variability and Frailty in End-Stage Kidney Disease
High blood pressure variability (BPV) is a predictor of cardiovascular events and all-cause mortality in people with end-s...
Journal Of Frailty & Aging
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Evaluation of Handgrip Strength Asymmetry to Assess Sarcopenia in Older Patients with Chronic Low Back Pain: A Retrospective Cross-Sectional Study
Handgrip strength (HGS) is a crucial measurement for diagnosing sarcopenia, and HGS asymmetry indicates functional impairm...
Journal Of Frailty & Aging
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Are General Practitioners More Reluctant to Give Advice for Exercise to Older Women? A Cross-Sectional Survey of European Adults
Despite the importance of physical exercise for older people, only a fraction of them receive advice to do so by primary c...
Journal Of Frailty & Aging
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