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The function of chaperones in the radioresistance of glioblastoma: a new insight into the current knowledge
The function of chaperones in the radioresistance of glioblastoma: a new insight into the current knowledge
Radiotherapy remains a cornerstone of brain tumor treatment; however, its effectiveness is frequently undermined by the de...
Rapidly progressive scalp and lung metastases with fatal pneumothorax in glioblastoma, IDH-wildtype, with and amplifications: a case report of clinical course and postmortem autopsy, including genetic analysis
Rapidly progressive scalp and lung metastases with fatal pneumothorax in glioblastoma, IDH-wildtype, with and amplifications: a case report of clinical course and postmortem autopsy, including genetic analysis
We report a rare case of extracranial metastases of a glioblastoma, IDH-wildtype, in a 77-year-old man who initially prese...
Targeting TGF-β signaling in glioblastoma: therapeutic implications and novel drug development strategies
Targeting TGF-β signaling in glioblastoma: therapeutic implications and novel drug development strategies
Glioma, a prevalent primary brain tumor, arises from the supporting cells of the central nervous system (CNS) and is categ...
Primary pigmented papillary epithelial tumor of the sella: case report and literature review
Primary pigmented papillary epithelial tumor of the sella: case report and literature review
Primary pigmented papillary epithelial tumor of the sella (PPPET) is a recently identified tumor entity that commonly orig...
Comprehensive molecular characterization of craniopharyngiomas using whole transcriptome and spatial transcriptomics approaches
Comprehensive molecular characterization of craniopharyngiomas using whole transcriptome and spatial transcriptomics approaches
Craniopharyngiomas (CPs) are rare benign brain tumors that are classified as WHO grade I, with two subtypes: adamantinomat...
Integrated analysis of MYC expression, 8q24.21 copy number, and recurrence patterns in astrocytoma, IDH-mutant
Integrated analysis of MYC expression, 8q24.21 copy number, and recurrence patterns in astrocytoma, IDH-mutant
Compared to oligodendrogliomas, astrocytomas may have a relatively higher frequency of intracranial remote recurrence, des...
Activated astrocytes drive the accumulation of apolipoprotein E at the brain tumor edge
Activated astrocytes drive the accumulation of apolipoprotein E at the brain tumor edge
While tumor-associated macrophages (TAMs) have been extensively studied, the role of tumor-associated astrocytes (TAAs) in...
How is rosette formation in brain tumours linked with cerebrospinal fluid spread?
How is rosette formation in brain tumours linked with cerebrospinal fluid spread?
Rosette formation, a characteristic histopathological feature of various paediatric brain tumours, appears to be linked wi...
A case of primary papillary epithelial tumor of the sella with reverse polarity and paired box 8 expression
A case of primary papillary epithelial tumor of the sella with reverse polarity and paired box 8 expression
Primary papillary epithelial tumor of the sella (PPETS) is a rare sellar neoplasm characterized by distinctive papillary a...
Emergence of NEC features in corticotroph PitNETs: primary tumor, radiation-induced transformation, or metastasis?
Emergence of NEC features in corticotroph PitNETs: primary tumor, radiation-induced transformation, or metastasis?
Pituitary neuroendocrine tumors (PitNETs) are generally benign, but a small subset may demonstrate aggressive behavior or ...
Meningioma with trabecular architecture: a harbinger of BAP1 deficiency
Meningioma with trabecular architecture: a harbinger of BAP1 deficiency
BRCA (BReast CAncer gene)-associated protein 1 (BAP1) is a tumor suppressor protein encoded by the BAP1 gene. BAP1 mutatio...
Diffuse midline glioma, H3K27-altered: a rare presentation with gliomatosis cerebri growth pattern and progression toward midline
Diffuse midline glioma, H3K27-altered: a rare presentation with gliomatosis cerebri growth pattern and progression toward midline
A limited number of cases involving non-midline lesions have been documented in diffuse midline glioma (DMG), H3K27-altere...
Ataxin-2 as a candidate blood biomarker for estimating disease status in cases of suspected glioblastoma recurrence
Ataxin-2 as a candidate blood biomarker for estimating disease status in cases of suspected glioblastoma recurrence
Differentiating pseudoprogression (PsP) from recurrence in cases of glioblastoma (GBM) after chemoradiotherapy is challeng...
Reappraisal of novel molecular parameters for meningioma grading by cIMPACT-NOW update 8 proposals
Reappraisal of novel molecular parameters for meningioma grading by cIMPACT-NOW update 8 proposals
Banan R, Abbetmeier-Basse M, Hong B, Dumitru CA, Sahm F, Nakamura M, Krauss JK, Hartmann C (2021) The prognostic significa...
Gyriform infiltration indicates tumor invasion burden of isocitrate dehydrogenase 1/2-wildtype gliomas
Gyriform infiltration indicates tumor invasion burden of isocitrate dehydrogenase 1/2-wildtype gliomas
Few robust radiological markers have been identified for predicting the molecular status of gliomas. Recently, gyriform in...
Primary sellar glomus tumor with mutation: an aggressive tumor of uncertain malignant potential
Primary sellar glomus tumor with mutation: an aggressive tumor of uncertain malignant potential
Glomus tumor (GT) is a mesenchymal neoplasm composed of modified perivascular cells exhibiting smooth muscle-like features...
Non-invasive Lobular Neoplasia: Review and Updates
Non-invasive lobular neoplasia (LN) encompasses atypical lobular hyperplasia (ALH), classic lobular carcinoma in situ (CLC...
An adapted & improved validation protocol for digital pathology implementation
Volume 42, Issue 4, July 2025, 150905Author links open overlay panel, , , , , , , , , AbstractDigital Pathology (DP) is tr...
Pancreatic neuroendocrine neoplasms: current paradigms and diagnostic challenges
The differential diagnosis for PanNENs mainly include solid pseudopapillary neoplasms (SPNs), acinar cell carcinoma (ACC),...
NCOA1/2/3-rearranged low-grade fibroblastic/myofibroblastic spindle cell tumors: including emerging entities beyond the WHO 5th edition of Bone and Soft Tissue Tumors — a systematic review
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Differential diagnosis of multiple myeloma
The diagnostic work-up of most plasma cell neoplasms with adequate sampling demonstrate clearcut morphology, classic clini...
Extrahepatic cholangiocarcinoma: Current concepts in histopathology, immunohistochemistry, and molecular diagnostics
Cholangiocarcinoma (CCA) makes up a diverse group of malignancies that originate from the biliary epithelium.1 While CCA i...
COVER (PMS 180&K) (p/u from previous issue w/updates)
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MASTHEAD (p/u from previous issue)
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EDITORIAL BOARD (p/u from previous issue)
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TABLE OF CONTENTS (p/u from previous issue w/updates)
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Primary cutaneous dedifferentiated and undifferentiated melanoma
As the ‘great mimicker’, melanoma is characterized by a high potential for phenotypic plasticity and a wide morphologic ra...
Head and neck xanthogranulomatous epithelial tumors/keratin-positive giant cell-rich tumors
In 2020 Fritchie et al.1 reported “xanthogranulomatous epithelial tumor” (XGET) a distinctive tumor of soft tissue and bon...
The expanding family of ALK-rearranged Mesenchymal Neoplasms
Volume 42, Issue 5, September 2025, 150947Author links open overlay panelAbstractThe increasing use of next generation seq...
Acral fibrochondromyxoid tumor – A review of the literature
Carina A. Dehner: Writing – original draft, Visualization, Supervision, Resources, Project administration, Investigation, ...
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