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CAR T cell therapy for children with rheumatic disease: the time is now
CAR T cell therapy for children with rheumatic disease: the time is now
Initial success with B cell-targeted chimeric antigen receptor (CAR) T cells for the treatment of systemic lupus erythemat...
Synovial fluid as a complex molecular pool contributing to knee osteoarthritis
Synovial fluid as a complex molecular pool contributing to knee osteoarthritis
The main homeostatic function of the synovial fluid is joint lubrication. However, during knee osteoarthritis (KOA), synov...
Platelets as drivers of immunothrombosis in rheumatic diseases
Platelets as drivers of immunothrombosis in rheumatic diseases
Platelets are central players in inflammatory and thrombotic responses that drive the onset and progression of rheumatic d...
Synovial fibroblast-mediated neovascularization in RA
A study provides insights into the factors that regulate synovial fibroblast interactions with endothelial cells in RA and...
Tissue-resident memory CD8+ T cells on the skin–joint route
Skin- and joint-resident CD8+ T cells that share clonality also share phenotypic similarities in psoriatic arthritis.
Nerandomilast slows progression of pulmonary fibrosis
The anti-fibrotic and anti-inflammatory agent nerandomilast has shown promise for the treatment of both idiopathic and pro...
Guided management of familial Mediterranean fever
Familial Mediterranean fever (FMF) is a monogenic autoinflammatory disorder with high prevalence in Mediterranean populati...
Insights into chondrocyte populations in cartilaginous tissues at the single-cell level
Insights into chondrocyte populations in cartilaginous tissues at the single-cell level
Chondrocyte biology is being revolutionized by single-cell multi-omics technologies, revealing cellular heterogeneity with...
Anti-Mi2 autoantibodies target the PHD fingers of SP140L and TIF1γ, while anti-TIF1γ autoantibodies primarily recognize epitopes outside the PHD region of TIF1γ.
Anti-Mi2 autoantibodies target the PHD fingers of SP140L and TIF1γ, while anti-TIF1γ autoantibodies primarily recognize epitopes outside the PHD region of TIF1γ.
medRxiv - The Preprint Server for Health Sciences
Decreased GPR55 expression links B-cell activation and vascular remodelling in atherosclerosis in early rheumatoid arthritis patients
Decreased GPR55 expression links B-cell activation and vascular remodelling in atherosclerosis in early rheumatoid arthritis patients
medRxiv - The Preprint Server for Health Sciences
The construction and validation of sub-phenotype-specific genetic risk scores in systemic lupus erythematosus: a novel approach using large-scale biobank data
The construction and validation of sub-phenotype-specific genetic risk scores in systemic lupus erythematosus: a novel approach using large-scale biobank data
medRxiv - The Preprint Server for Health Sciences
Trends in hospitalizations and mortality rates for anti-neutrophil cytoplasmic antibody-associated vasculitis in Mexico: Results from a Nationwide Health Registry
Trends in hospitalizations and mortality rates for anti-neutrophil cytoplasmic antibody-associated vasculitis in Mexico: Results from a Nationwide Health Registry
medRxiv - The Preprint Server for Health Sciences
Validation of patient-reported outcome measures for dactylitis, psoriatic skin and nail disease, and uveitis in patients with psoriatic arthritis in routine care
Validation of patient-reported outcome measures for dactylitis, psoriatic skin and nail disease, and uveitis in patients with psoriatic arthritis in routine care
medRxiv - The Preprint Server for Health Sciences
The Michael Mason Prize: Development and feasibility testing of a complex intervention to improve adherence to fracture prevention medicine using a person-centred approach
The Michael Mason Prize: Development and feasibility testing of a complex intervention to improve adherence to fracture prevention medicine using a person-centred approach
medRxiv - The Preprint Server for Health Sciences
Prospective SARS-CoV-2 Booster Vaccination in Immunosuppressant-Treated Systemic Autoimmune Disease Patients in a Randomized Controlled Trial
Prospective SARS-CoV-2 Booster Vaccination in Immunosuppressant-Treated Systemic Autoimmune Disease Patients in a Randomized Controlled Trial
medRxiv - The Preprint Server for Health Sciences
Prevalence, Incidence, and Mortality of Autoimmune Diseases Among Adolescents and Young Adults in Mexico: An Analysis Based on the Global Burden of Disease Study 2021
Prevalence, Incidence, and Mortality of Autoimmune Diseases Among Adolescents and Young Adults in Mexico: An Analysis Based on the Global Burden of Disease Study 2021
medRxiv - The Preprint Server for Health Sciences
Optimizing the Clinical Application of Rheumatology Guidelines Using Large Language Models: A Retrieval-Augmented Generation Framework Integrating ACR and EULAR Recommendations
Optimizing the Clinical Application of Rheumatology Guidelines Using Large Language Models: A Retrieval-Augmented Generation Framework Integrating ACR and EULAR Recommendations
medRxiv - The Preprint Server for Health Sciences
A cross-sectional analysis of the vaginal microenvironment in rheumatoid arthritis
A cross-sectional analysis of the vaginal microenvironment in rheumatoid arthritis
medRxiv - The Preprint Server for Health Sciences
Assessment of pain types in recently diagnosed patients with inflammatory arthritis
Assessment of pain types in recently diagnosed patients with inflammatory arthritis
medRxiv - The Preprint Server for Health Sciences
Cerebellar tissue properties alterations in fibromyalgia: a T1w/T2w ratio study
Cerebellar tissue properties alterations in fibromyalgia: a T1w/T2w ratio study
medRxiv - The Preprint Server for Health Sciences
Healthcare use in individuals with rheumatoid arthritis during the COVID-19 pandemic and beyond: A cohort study in three nations of the UK
Healthcare use in individuals with rheumatoid arthritis during the COVID-19 pandemic and beyond: A cohort study in three nations of the UK
medRxiv - The Preprint Server for Health Sciences
Autoimmune and inflammatory comorbidity patterns in rheumatoid arthritis: temporal trajectories and impact on persistence on DMARD therapy
Autoimmune and inflammatory comorbidity patterns in rheumatoid arthritis: temporal trajectories and impact on persistence on DMARD therapy
medRxiv - The Preprint Server for Health Sciences
Mapping the intersection of social status and comorbidity in knee osteoarthritis: a WOMAC-based study
Mapping the intersection of social status and comorbidity in knee osteoarthritis: a WOMAC-based study
medRxiv - The Preprint Server for Health Sciences
Genetic and Epigenetic Dysregulation of CR1 is Associated with Catastrophic Antiphospholipid Syndrome (CAPS)
Genetic and Epigenetic Dysregulation of CR1 is Associated with Catastrophic Antiphospholipid Syndrome (CAPS)
medRxiv - The Preprint Server for Health Sciences
Manual Validation of an Algorithm for Identifying Osteoarthritis within the Centralized Interactive Phenomics Resource of the Million Veteran Program
Manual Validation of an Algorithm for Identifying Osteoarthritis within the Centralized Interactive Phenomics Resource of the Million Veteran Program
medRxiv - The Preprint Server for Health Sciences
Local immunoglobulin expression in myositis is associated with interferon gamma signaling and correlates with disease activity.
Local immunoglobulin expression in myositis is associated with interferon gamma signaling and correlates with disease activity.
medRxiv - The Preprint Server for Health Sciences
Activated Dendritic Cell Subsets Characterize Muscle of Inclusion Body Myositis Patients and Correlate with KLRG1+ and TBX21+ CD8+ T cells
Activated Dendritic Cell Subsets Characterize Muscle of Inclusion Body Myositis Patients and Correlate with KLRG1+ and TBX21+ CD8+ T cells
medRxiv - The Preprint Server for Health Sciences
Bayesian trial of adalimumab versus secukinumab for children with juvenile idiopathic arthritis associated uveitis or chronic anterior uveitis
Bayesian trial of adalimumab versus secukinumab for children with juvenile idiopathic arthritis associated uveitis or chronic anterior uveitis
Juvenile idiopathic arthritis (JIA)-associated uveitis and chronic anterior uveitis in children may result in permanent si...
Insights from the 2024 pediatric rheumatology basic/translational years in review
Insights from the 2024 pediatric rheumatology basic/translational years in review
Advances in Pediatric Rheumatology are driven by mechanistic insights from basic and translational science. We have select...
Management of childhood-onset systemic lupus erythematosus (cSLE) over the last two decades in Spain
Management of childhood-onset systemic lupus erythematosus (cSLE) over the last two decades in Spain
Childhood-onset systemic lupus erythematosus (cSLE) is a chronic multisystemic autoimmune disease with a more severe and l...
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