SCI Abstract

search
+
Digital Health and Self-Management in Idiopathic Inflammatory Myopathies: A Missed Opportunity?
Digital Health and Self-Management in Idiopathic Inflammatory Myopathies: A Missed Opportunity?
This paper explored the potential of digital health in idiopathic inflammatory myopathies (IIMs), with a focus on self-man...
Keratinocytes – Amplifiers of Immune Responses in Systemic Lupus Erythematosus
Keratinocytes – Amplifiers of Immune Responses in Systemic Lupus Erythematosus
Epithelial cells have been acknowledged as important players in autoimmune diseases by directing and enhancing inflammator...
Unveiling the Potential of Probiotics in Osteoarthritis Management
Unveiling the Potential of Probiotics in Osteoarthritis Management
Osteoarthritis (OA), a highly prevalent degenerative joint disease, is of increasing concern due to its debilitating natur...
Immune Checkpoint Inhibitor Associated Rheumatoid Arthritis
Immune Checkpoint Inhibitor Associated Rheumatoid Arthritis
Immune checkpoint inhibitors (ICI) have revolutionized cancer therapy over the past decade. Unfortunately, immune related ...
How to Distinguish Non-Inflammatory from Inflammatory Pain in RA?
How to Distinguish Non-Inflammatory from Inflammatory Pain in RA?
Managing non-inflammatory pain in rheumatoid arthritis (RA) can be a huge burden for the rheumatologist. Pain that persist...
Rheumatoid Arthritis-Associated Interstitial Lung Disease (RA-ILD): Update on Prevalence, Risk Factors, Pathogenesis, and Therapy
Rheumatoid Arthritis-Associated Interstitial Lung Disease (RA-ILD): Update on Prevalence, Risk Factors, Pathogenesis, and Therapy
Rheumatoid arthritis is frequently complicated by interstitial lung disease (RA-ILD), an underappreciated contributor to e...
Treatment of Reactive Arthritis with Biological Agents
Treatment of Reactive Arthritis with Biological Agents
Reactive arthritis (ReA) is an inflammatory joint condition triggered by an infection elsewhere in the body, and this revi...
Recent Updates on the Pathogenesis of Inflammatory Myopathies
Recent Updates on the Pathogenesis of Inflammatory Myopathies
This review aims to provide a comprehensive and updated overview of autoimmune myopathies, with a special focus on the lat...
Newer Autoantibodies and Laboratory Assessments in Myositis
Newer Autoantibodies and Laboratory Assessments in Myositis
We aim to describe the immunoassays that have been used for myositis autoantibody discovery with a focus on newer methods....
Incremental Cardiovascular Risk of Menopause in Women with Psoriasis, Psoriatic Arthritis or Spondyloarthritis?
Incremental Cardiovascular Risk of Menopause in Women with Psoriasis, Psoriatic Arthritis or Spondyloarthritis?
This narrative review aims to discuss the most recent studies regarding the risk of cardiovascular disease (CVD) in women ...
Updating the 2019 ACR/SAA/SPARTAN Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis (SPARTAN 2024 Annual Meeting Proceedings)
Updating the 2019 ACR/SAA/SPARTAN Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis (SPARTAN 2024 Annual Meeting Proceedings)
Since the publication of the 2019 American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Re...
The Role of Podocytes in Lupus Pathology
The Role of Podocytes in Lupus Pathology
Kidney injury due to lupus nephritis (LN) is a severe and sometimes life-threatening sequela of systemic lupus erythematos...
Year in Review: Novel Insights in the Pathogenesis of Spondyloarthritis – SPARTAN 2024 Annual Meeting Proceedings
Year in Review: Novel Insights in the Pathogenesis of Spondyloarthritis – SPARTAN 2024 Annual Meeting Proceedings
The canonical pathogenesis of spondyloarthritis (SpA) involves inflammation driven by HLA-B27, type 3 immunity, and gut mi...
Fibromyalgia comorbidity in Systemic Lupus Erythematosus patients: assessing impact on quality of life
Fibromyalgia comorbidity in Systemic Lupus Erythematosus patients: assessing impact on quality of life
The prevalence of Fibromyalgia in patients with Systemic Lupus Erythematosus (SLE) is significantly higher compared to the...
Investigating the causal relationship between immune factors and ankylosing spondylitis: insights from a Mendelian Randomization study
Investigating the causal relationship between immune factors and ankylosing spondylitis: insights from a Mendelian Randomization study
Despite previous studies indicating a close relationship between immune system and ankylosing spondylitis (AS), the causal...
Hck promotes IL-1β-induced extracellular matrix degradation, inflammation, and apoptosis in osteoarthritis via activation of the JAK-STAT3 signaling pathway
Hck promotes IL-1β-induced extracellular matrix degradation, inflammation, and apoptosis in osteoarthritis via activation of the JAK-STAT3 signaling pathway
We investigated role of haematopoietic cell kinase (Hck) in osteoarthritis (OA) and to explore the underlying mechanisms d...
Integrated safety analysis of tofacitinib from Phase 2 and 3 trials of patients with ankylosing spondylitis
Integrated safety analysis of tofacitinib from Phase 2 and 3 trials of patients with ankylosing spondylitis
Describe tofacitinib safety from an integrated analysis of randomized controlled trials (RCTs) in patients with ankylosing...
Evaluating the role of active TGF-β1 as inflammatory biomarker in Kashmiri (North-Indian) patients with systemic sclerosis: a case-control study
Evaluating the role of active TGF-β1 as inflammatory biomarker in Kashmiri (North-Indian) patients with systemic sclerosis: a case-control study
As a master immune system regulator, transforming growth factor β1 (TGF-β1) is closely linked to the complicated...
Dupuytren contracture treatments compared
In an open-label clinical trial, collagenase injection was not noninferior to limited fasciectomy for the treatment of Dup...
The management of adult and paediatric uveitis for rheumatologists
The management of adult and paediatric uveitis for rheumatologists
Uveitis encompasses multiple different conditions that are all characterized by intra-ocular inflammation. Uveitis occurs ...
The essential roles of memory B cells in the pathogenesis of systemic lupus erythematosus
The essential roles of memory B cells in the pathogenesis of systemic lupus erythematosus
Emerging evidence indicates that memory B cells are dysfunctional in systemic lupus erythematosus (SLE). They are hyporesp...
Publisher Correction: Recent advances in the diagnosis and management of neuropsychiatric lupus
Authors and AffiliationsDivision of Rheumatology, Department of Medicine, Dalhousie University and Queen Elizabeth II Heal...
The emergence of SLE-causing UNC93B1 variants in 2024
During the past year, four studies have reported ten mutations in UNC93B1, which encodes the Toll-like receptor (TLR) chap...
The quest for targetable pain mechanisms in 2024
Studies published in 2024 suggest that although the repurposing of established rheumatology drugs seems to deliver increme...
EULAR and PReS bridge the age gap in Still’s disease
EULAR and PReS bridge the age gap in Still’s disease
EULAR and the Paediatric Rheumatology European Society (PReS) now view systemic juvenile idiopathic arthritis and adult-on...
An update on autoantibodies in the idiopathic inflammatory myopathies
An update on autoantibodies in the idiopathic inflammatory myopathies
Myositis-specific autoantibodies (MSAs) have become pivotal biomarkers for idiopathic inflammatory myopathies and have rev...
Elevated serum interferon-α2 associates with activity and flare risk in Juvenile-onset Systemic Lupus Erythematosus
Elevated serum interferon-α2 associates with activity and flare risk in Juvenile-onset Systemic Lupus Erythematosus
AbstractObjectives. This study investigated serum IFN-α2 as a putative marker of disease activity and predictor of disease...
Positive feedback loop PU.1-IL9 in Th9 promotes rheumatoid arthritis development
Positive feedback loop PU.1-IL9 in Th9 promotes rheumatoid arthritis development
Materials and methodsPatients and normal volunteersThis study was approved by the Biomedical Ethics Committee of Anhui Med...
New WHO ACPA standard enables standardisation among anti-CCP2 assays, but not other ACPA assays using different antigens
New WHO ACPA standard enables standardisation among anti-CCP2 assays, but not other ACPA assays using different antigens
Antibodies to citrullinated protein/peptide (ACPA) are established biomarkers for diagnosis and classification of rheumato...
Acod1-mediated inhibition of aerobic glycolysis suppresses osteoclast differentiation and attenuates bone erosion in arthritis
Acod1-mediated inhibition of aerobic glycolysis suppresses osteoclast differentiation and attenuates bone erosion in arthritis
IntroductionRheumatoid arthritis (RA) is a chronic inflammatory joint disease that affects up to 1% of the population.1 Th...
Load More
format_indent_increase