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Rational search for natural antimicrobial compounds: relevance of sesquiterpene lactones
Rational search for natural antimicrobial compounds: relevance of sesquiterpene lactones
Antimicrobial resistance is one of the most pressing global health challenges, as many pathogens are rapidly evolving to e...
New sesquiterpenoids with anti-inflammatory effects from phytopathogenic fungus  11134
New sesquiterpenoids with anti-inflammatory effects from phytopathogenic fungus 11134
Sesquiterpenoids represent a structurally diverse class of natural products widely recognized for their ecological signifi...
Six pairs of enantiomeric prenylated flavonoids with cytotoxic activities from  Maxim
Six pairs of enantiomeric prenylated flavonoids with cytotoxic activities from Maxim
In this work, six pairs of undescribed enantiomeric prenylated flavonoids, ( ±)-epimesatines J–O (1a/1b&#...
Concise syntheses of natural diarylheptanoids containing a 1,4-pentadiene unit
Concise syntheses of natural diarylheptanoids containing a 1,4-pentadiene unit
Two concise and efficient synthetic routes were developed for the synthesis of three 1,7-diarylheptanoids (1–3) cont...
Enantiomeric diarylheptanoids from   var.  and their -glucosidase inhibitory activity
Enantiomeric diarylheptanoids from var. and their -glucosidase inhibitory activity
Otteacumienes G–K (1–5), five pairs of enantiomeric diarylheptanoids, along with one undescribed diarylheptano...
Polyprenylated acylphloroglucinols from  species and structural revision of seven analogues
Polyprenylated acylphloroglucinols from species and structural revision of seven analogues
Our continuous study of the fruits of Garcinia xanthochymus and Garcinia subelliptica led to the isolation and structural ...
Chemical constituents of  leaves and their anti-rheumatoid arthritis activity in vitro
Chemical constituents of leaves and their anti-rheumatoid arthritis activity in vitro
Two new together with 32 known compounds were isolated from the leaves of Lycium barbarum. Their structures were elucidate...
Mechanisms of action and resistance prevention of synergistic thymol and carvacrol combinations with antibiotics inand
Mechanisms of action and resistance prevention of synergistic thymol and carvacrol combinations with antibiotics inand
The use of natural products as antibiotic adjuvants to enhance efficacy and mitigate resistance is increasingly recognized...
Design of 20-deoxyingenol-esters-based PKC agonists and their lysosome biogenesis-enhancing activity
Design of 20-deoxyingenol-esters-based PKC agonists and their lysosome biogenesis-enhancing activity
The activation of conventional (α) and novel (δ) protein kinase C (PKC) isoforms promotes lysosomal biogenesis, ...
Review on NMR spectroscopic data and recent analytical methods of aristolochic acids and derivatives in  herbs
Review on NMR spectroscopic data and recent analytical methods of aristolochic acids and derivatives in herbs
Aristolochic acids (AAs) are an important group of secondary metabolites in the genus Aristolochia. The presence of aristo...
Bioprospecting cultivable bacteria associated with deep sea (mesopelagic) fish of the North Atlantic Ocean
Bioprospecting cultivable bacteria associated with deep sea (mesopelagic) fish of the North Atlantic Ocean
The microbiota associated with fish is increasingly recognized as a valuable source of bioactive metabolites for pharmaceu...
Exploring the antineoplastic potential of α-mangostin in breast cancer
Exploring the antineoplastic potential of α-mangostin in breast cancer
Among women, breast cancer is the most frequently diagnosed cancer and the leading cause of cancer-related mortality globa...
Unlocking potent anti-tuberculosis natural products through structure–activity relationship analysis
Unlocking potent anti-tuberculosis natural products through structure–activity relationship analysis
Tuberculosis (TB) remains a world health problem due to the high number of affected individuals, high mortality rates, pro...
Chemoprofiling of  (Loisel.) P. Delforge leaves reveals predominance of gastrodigenin and structurally related compounds
Chemoprofiling of (Loisel.) P. Delforge leaves reveals predominance of gastrodigenin and structurally related compounds
The purpose of this study was to phytochemically profile Himantoglossum robertianum leaves. In fact, despite its wide dist...
Subgroup analysis: fever vs outcome
Volume 89, October 2025, 155170Author links open overlay panel, Section snippetsCRediT authorship contribution statementDa...
Authors reply: “Can extracorporeal CO2 removal facilitate ultraprotective ventilation in severe ARDS? A Latin American case series”
Volume 89, October 2025, 155155Author links open overlay panel, , , , , Section snippetsRegarding the analysis of response...
Letter to editor regarding, “Association of vasopressor use during renal replacement therapy and mortality”
Volume 89, October 2025, 155157Author links open overlay panelSection snippetsCRediT authorship contribution statementGurd...
Authors reply: “Vasopressor use during renal replacement therapy”
Volume 89, October 2025, 155156Author links open overlay panel, , Section snippetsCRediT authorship contribution statement...
Authors reply: “Pulse oximetry beyond oxygen saturation: Early waveform characteristics in sepsis patients with adverse outcomes”
Volume 89, October 2025, 155167Author links open overlay panel, , , , , Section snippetsTechnical feasibility and clinical...
Major publications in the critical care pharmacotherapy literature: 2024
The volume of medical publications has increased significantly over the past decade, stemming from a surge in research sub...