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White Matter Hyperintensities Contribute to Early Cortical Thinning in Addition to Tau in Aging
Available online 9 July 2025Author links open overlay panel, , Highlights•WMH yield early cortical thinning in AD beyond w...
Comparison of CSF neurofilament light chain and total tau as neurodegeneration markers: associations with synaptic markers and cognitive outcomes
Clinically, Alzheimer`s disease (AD) is a progressive, neurodegenerative disease leading to neurodegeneration and subseque...
Effects of age on the strategic control of recollected content as reflected by modulation of neural correlates of scene retrieval
Neuroimaging studies have often implicated encoding processes in age-related episodic memory decline (see Maillet and Raja...
How is self-reported sleep-disordered breathing linked with biomarkers of Alzheimer’s disease?
The ADNI is a multisite initiative to prevent and treat AD. The MRI and CSF biomarkers, as well as the clinical data used ...
Explaining tip-of-the-tongue experiences in older adults: The role of brain-based and cardiorespiratory fitness factors
Cognitive decline associated with healthy ageing is multifactorial: brain-based and lifestyle factors uniquely and jointly...
Age-related differences in cerebral morphology and microstructure in rhesus macaques
Volume 154, October 2025, Pages 37-46Author links open overlay panel, , , , , Highlights•Age-related morphometric differen...
Two-year changes in hippocampal subfield volumes are age-dependent across the lifespan
The hippocampus (Hc) is a heterogeneous structure composed of cytoarchitectonically distinct regions (subfields): dentate ...
Balance training improves postural control and performance-related prefrontal brain activation in healthy older adults: Results of a six-month randomized controlled training intervention
Age-related deterioration in postural control is an important factor decreasing quality of life. Functional neuroimaging s...
Identifying lifestyle risk factors that discriminate memory trajectories: Differential findings across racial and ethnic groups in older adults
Volume 154, October 2025, Pages 84-91Author links open overlay panel, , , , , , , , , Highlights•Three latent classes of m...
Evaluating the link between hearing loss and Alzheimer’s disease neuropathology: A systematic review and meta-analysis
Hearing loss has been linked with cognitive decline and increased dementia risk. The neurobiological mechanisms underlying...
Neurobiological effects of exergame interventions in older adults with or without a neurocognitive disorder: A systematic review
Volume 154, October 2025, Pages 47-61Author links open overlay panel, , , , , Highlights•Exergames (EG) changed brain stru...
Serum HDL-cholesterol is associated with the clinical-biological profile of early-stage Parkinson’s disease patients independently of APOE
Emerging evidence highlights a possible interplay between serum lipid profiles and Parkinson’s disease (PD), but the biolo...
Epigenetic age is associated with regional brain aging along the sensorimotor-to-association axis of cortical organization
Volume 155, November 2025, Pages 8-12Author links open overlay panel, , , , , , , , , Highlights•Epigenetic age is related...
Corrigendum to: A clinical, molecular genetics and pathological study of a FTDP-17 family with a heterozygous splicing variant c.823–10 G>T at the intron 9/exon 10 of the MAPT gene
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Hippocampal atrophy over two years in relation to tau, amyloid-β and memory in older adults
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Locus coeruleus MRI contrast, cerebral perfusion, and plasma Alzheimer’s disease biomarkers in older adults
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Relationships of functional connectivity of motor cortex, primary somatosensory cortex, and cerebellum to balance performance in middle-aged and older adults
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Exploring the links among brain iron accumulation, cognitive performance, and dietary intake in older adults: A longitudinal MRI study
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Amyloid pathology and cognitive impairment in hAβ-KI and APPSAA-KI mouse models of Alzheimer's disease
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Hearing loss and its relation to longitudinal changes in white matter microstructure in older adults: The Rotterdam Study
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Longitudinal relationships between Aβ and tau to executive function and memory in cognitively normal older adults
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Alcohol consumption confers lasting impacts on prefrontal cortical neuron intrinsic excitability and spontaneous neurotransmitter signaling in the aging brain in mice
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Increased inflammation in older high-pressure glaucoma mice
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M1 muscarinic receptor activation reverses age-related memory updating impairment in mice
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A neural implementation of cognitive reserve: Insights from a longitudinal fMRI study of set-switching in aging
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Hypertension may associate with cerebral small vessel disease and infarcts through the pathway of intracranial atherosclerosis
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Calcineurin/NFAT inhibitors maintain cognition in a preclinical prevention study in an aging canine model of Alzheimer disease
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Cross-sectional and longitudinal relationships among blood-brain barrier disruption, Alzheimer's disease biomarkers, and cognition in cognitively normal older adults
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Effects of age and dietary methionine restriction on cognitive and behavioural phenotypes in the rTg4510 mouse model of frontotemporal dementia
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Cerebral white matter hyperintensity volumes: Normative age- and sex-specific values from 15 population-based cohorts comprising 14,876 individuals
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