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The bidirectional regulatory effect of TXNRD2 methylation in patients with chronic heart failure and its nonlinear dose-response relationship with key clinical parameters
The bidirectional regulatory effect of TXNRD2 methylation in patients with chronic heart failure and its nonlinear dose-response relationship with key clinical parameters
The research focused on examining CpG methylation within the TXNRD2 promoter area in chronic heart failure (CHF) patients,...
Blood cardioplegia or custodiol for myocardial protection during valvular or aortic surgery: a propensity score adjusted comparison
Blood cardioplegia or custodiol for myocardial protection during valvular or aortic surgery: a propensity score adjusted comparison
There is no solid evidence on the clinical benefits of blood cardioplegia or Custodiol™ in procedures other than cor...
Stentless balloon angioplasty preserving growth in adolescent congenital focal abdominal aortic coarctation: a case report
Stentless balloon angioplasty preserving growth in adolescent congenital focal abdominal aortic coarctation: a case report
Congenital focal abdominal aortic coarctation (CAAC) is a rare vascular malformation frequently misdiagnosed as mid-aortic...
Rare case of a massive anterior mediastinal schwannoma causing cardiac compression with concurrent cervical spine lesion causing spinal cord compression
Rare case of a massive anterior mediastinal schwannoma causing cardiac compression with concurrent cervical spine lesion causing spinal cord compression
Schwannoma is the most common neurogenic tumor in the posterior mediastinum, however it is rarely found in the anterior me...
Correlation of carotid plaque and peripheral carotid adipose tissue characteristics with coronary computed tomography angiography-based fractional flow reserve
Correlation of carotid plaque and peripheral carotid adipose tissue characteristics with coronary computed tomography angiography-based fractional flow reserve
The study aimed to investigate the correlation of carotid plaque and peripheral carotid adipose tissue (PCAT) characterist...
Machine learning in the prevention of heart failure
Machine learning in the prevention of heart failure
Heart failure (HF) is a global pandemic with a growing prevalence and is a growing burden on the healthcare system. Machin...
The chronobiology of human heart failure: clinical implications and therapeutic opportunities
The chronobiology of human heart failure: clinical implications and therapeutic opportunities
Circadian variation in cardiovascular and metabolic dynamics arises from interactions between intrinsic rhythms and extrin...
Sodium-glucose cotransporter-2 inhibitors in acute myocardial infarction: a systematic review and meta-analysis of randomized controlled trials
Sodium-glucose cotransporter-2 inhibitors in acute myocardial infarction: a systematic review and meta-analysis of randomized controlled trials
We aimed to assess the efficacy and safety of sodium-glucose cotransporter-2 inhibitors (SGLT2i) versus placebo, initiated...
Dietary sodium intake restriction in patients with heart failure: an overview of systematic reviews
Dietary sodium intake restriction in patients with heart failure: an overview of systematic reviews
This study aimed to identify, assess, and summarize systematic reviews on dietary sodium intake restrictions for patients ...
In-hospital initiation of sodium-glucose co-transporter-2 inhibitors in patients with acute heart failure
In-hospital initiation of sodium-glucose co-transporter-2 inhibitors in patients with acute heart failure
Sodium-glucose cotransporter-2 (SGLT2) inhibitors provide cardiovascular and kidney benefits to patients with heart failur...
Heart failure with reduced ejection fraction and chronic kidney disease: a focus on therapies and interventions
Heart failure with reduced ejection fraction and chronic kidney disease: a focus on therapies and interventions
In heart failure with reduced ejection fraction (HFrEF), the presence of concomitant chronic kidney disease (CKD) predicts...
Adrenal crisis-induced cardiogenic shock (ACCS): a comprehensive review
Adrenal crisis-induced cardiogenic shock (ACCS): a comprehensive review
Adrenal insufficiency (AI) is a disorder in which inadequate glucocorticoid and mineralocorticoid hormone production leads...
Heart failure with preserved ejection fraction and atrial fibrillation: catheter ablation vs. standard medical therapy — a systematic review and meta-analysis
Heart failure with preserved ejection fraction and atrial fibrillation: catheter ablation vs. standard medical therapy — a systematic review and meta-analysis
The latest guidelines advocate for catheter ablation (CA) over standard medical therapy (SMT) for managing atrial fibrilla...
Contextualizing the results of HELIOS-B in the broader landscape of clinical trials for the treatment of transthyretin cardiac amyloidosis
Contextualizing the results of HELIOS-B in the broader landscape of clinical trials for the treatment of transthyretin cardiac amyloidosis
This focused review will highlight the results of HELIOS-B, the first randomized outcomes trial evaluating a gene silencin...
The sympathetic nervous system in heart failure with preserved ejection fraction
The sympathetic nervous system in heart failure with preserved ejection fraction
The sympathetic nervous system (SNS) is a major mediator of cardiovascular physiology during exercise in healthy people. H...
GLP-1 receptor agonists as promising anti-inflammatory agents in heart failure with preserved ejection fraction
GLP-1 receptor agonists as promising anti-inflammatory agents in heart failure with preserved ejection fraction
Heart Failure with Preserved Ejection Fraction (HFpEF) represents a significant challenge in modern cardiovascular medicin...
Modulating energy metabolism to treat non-obstructive hypertrophic cardiomyopathy? Insights from IMPROVE-HCM
Modulating energy metabolism to treat non-obstructive hypertrophic cardiomyopathy? Insights from IMPROVE-HCM
Hypertrophic cardiomyopathy (HCM) is the most common genetic heart disease worldwide and may present with or without dynam...
The many faces of SCN5A pathogenic variants: from channelopathy to cardiomyopathy
The many faces of SCN5A pathogenic variants: from channelopathy to cardiomyopathy
The SCN5A gene encodes the alpha subunit of the cardiac sodium channel, which plays a fundamental role in the generation a...
Changing the paradigm in heart failure: shifting from treatment to prevention
Changing the paradigm in heart failure: shifting from treatment to prevention
Heart failure (HF) poses a major global health challenge with rising prevalence, significant morbidity and mortality, and ...
Beyond weight loss: the potential of glucagon-like peptide-1 receptor agonists for treating heart failure with preserved ejection fraction
Beyond weight loss: the potential of glucagon-like peptide-1 receptor agonists for treating heart failure with preserved ejection fraction
Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous syndrome with various phenotypes, and obesity is...
BNP and NT-proBNP as prognostic biomarkers for the prediction of adverse outcomes in HFpEF patients: A systematic review and meta-analysis
BNP and NT-proBNP as prognostic biomarkers for the prediction of adverse outcomes in HFpEF patients: A systematic review and meta-analysis
Heart failure with preserved ejection fraction (HFpEF) presents a challenge in clinical practice due to its complexity and...
The role of coronary microcirculation in heart failure with preserved ejection fraction: An unceasing odyssey
The role of coronary microcirculation in heart failure with preserved ejection fraction: An unceasing odyssey
Heart failure with preserved ejection fraction (HFpEF) represents an entity with complex pathophysiologic pathways, among ...
Prognostic impact of the metabolic syndrome and its components in acute type a aortic dissection after surgery: a retrospective study
Prognostic impact of the metabolic syndrome and its components in acute type a aortic dissection after surgery: a retrospective study
This study aimed to explore whether metabolic syndrome (MetS) and its components are associated with poor outcomes in pati...
The effect of cardiac rehabilitation prescription on medication complications and ET-1, WMSI in elderly patients with coronary heart disease
The effect of cardiac rehabilitation prescription on medication complications and ET-1, WMSI in elderly patients with coronary heart disease
To explore the effects of cardiac rehabilitation prescriptions on medication complications, Endothelin 1 (ET-1), and Wall ...
LncRNA CASC9 facilitates papillary thyroid cancer development and doxorubicin resistance via miR-28-3p/BCL-2 axis and PI3K/AKT signaling pathway
LncRNA CASC9 facilitates papillary thyroid cancer development and doxorubicin resistance via miR-28-3p/BCL-2 axis and PI3K/AKT signaling pathway
Papillary thyroid cancer (PTC) is a malignant tumor that poses a serious threat to human health. LncRNA CASC9 serves as an...
National outcomes for dementia patients undergoing cardiac surgery in a pre-structural era
National outcomes for dementia patients undergoing cardiac surgery in a pre-structural era
With an aging population and higher prevalence of dementia, there is a paucity of data regarding dementia patients undergo...
Contemporary comparative surgical outcomes of type A aortic dissection in US and China: an analysis of the national inpatient sample database and a Chinese multi-institutional registry
Contemporary comparative surgical outcomes of type A aortic dissection in US and China: an analysis of the national inpatient sample database and a Chinese multi-institutional registry
To investigate the contemporary comparative inpatient prognosis among US and Chinese patients with type A aortic dissectio...
Feasibility of epicardial implantation of medtronic 3830 lead in a pediatric patient : case report
Feasibility of epicardial implantation of medtronic 3830 lead in a pediatric patient : case report
High-grade atrioventricular block is the primary reason for epicardial permanent pacemaker implantation during the periope...
Early surgery to prevent embolic events in patients with infective endocarditis: a comprehensive review
Early surgery to prevent embolic events in patients with infective endocarditis: a comprehensive review
Infective endocarditis (IE) is a dangerous and lethal illness with high mortality rates. One of the main indications for s...
Acute hepatotoxicity of intravenous amiodarone in a Becker muscular dystrophy patient with decompensated heart failing and ABCB4 gene mutation: as assessed for causality using the updated RUCAM
Acute hepatotoxicity of intravenous amiodarone in a Becker muscular dystrophy patient with decompensated heart failing and ABCB4 gene mutation: as assessed for causality using the updated RUCAM
Cardiac dysfunction, including arrhythmias, may be one of the main clinical manifestations of Becker muscular dystrophy (B...
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