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Machine learning in the prevention of heart failure
Machine learning in the prevention of heart failure
Heart failure (HF) is a global pandemic with a growing prevalence and is a growing burden on the healthcare system. Machin...
The chronobiology of human heart failure: clinical implications and therapeutic opportunities
The chronobiology of human heart failure: clinical implications and therapeutic opportunities
Circadian variation in cardiovascular and metabolic dynamics arises from interactions between intrinsic rhythms and extrin...
Sodium-glucose cotransporter-2 inhibitors in acute myocardial infarction: a systematic review and meta-analysis of randomized controlled trials
Sodium-glucose cotransporter-2 inhibitors in acute myocardial infarction: a systematic review and meta-analysis of randomized controlled trials
We aimed to assess the efficacy and safety of sodium-glucose cotransporter-2 inhibitors (SGLT2i) versus placebo, initiated...
Dietary sodium intake restriction in patients with heart failure: an overview of systematic reviews
Dietary sodium intake restriction in patients with heart failure: an overview of systematic reviews
This study aimed to identify, assess, and summarize systematic reviews on dietary sodium intake restrictions for patients ...
In-hospital initiation of sodium-glucose co-transporter-2 inhibitors in patients with acute heart failure
In-hospital initiation of sodium-glucose co-transporter-2 inhibitors in patients with acute heart failure
Sodium-glucose cotransporter-2 (SGLT2) inhibitors provide cardiovascular and kidney benefits to patients with heart failur...
Heart failure with reduced ejection fraction and chronic kidney disease: a focus on therapies and interventions
Heart failure with reduced ejection fraction and chronic kidney disease: a focus on therapies and interventions
In heart failure with reduced ejection fraction (HFrEF), the presence of concomitant chronic kidney disease (CKD) predicts...
Adrenal crisis-induced cardiogenic shock (ACCS): a comprehensive review
Adrenal crisis-induced cardiogenic shock (ACCS): a comprehensive review
Adrenal insufficiency (AI) is a disorder in which inadequate glucocorticoid and mineralocorticoid hormone production leads...
Heart failure with preserved ejection fraction and atrial fibrillation: catheter ablation vs. standard medical therapy — a systematic review and meta-analysis
Heart failure with preserved ejection fraction and atrial fibrillation: catheter ablation vs. standard medical therapy — a systematic review and meta-analysis
The latest guidelines advocate for catheter ablation (CA) over standard medical therapy (SMT) for managing atrial fibrilla...
Contextualizing the results of HELIOS-B in the broader landscape of clinical trials for the treatment of transthyretin cardiac amyloidosis
Contextualizing the results of HELIOS-B in the broader landscape of clinical trials for the treatment of transthyretin cardiac amyloidosis
This focused review will highlight the results of HELIOS-B, the first randomized outcomes trial evaluating a gene silencin...
The sympathetic nervous system in heart failure with preserved ejection fraction
The sympathetic nervous system in heart failure with preserved ejection fraction
The sympathetic nervous system (SNS) is a major mediator of cardiovascular physiology during exercise in healthy people. H...
GLP-1 receptor agonists as promising anti-inflammatory agents in heart failure with preserved ejection fraction
GLP-1 receptor agonists as promising anti-inflammatory agents in heart failure with preserved ejection fraction
Heart Failure with Preserved Ejection Fraction (HFpEF) represents a significant challenge in modern cardiovascular medicin...
Modulating energy metabolism to treat non-obstructive hypertrophic cardiomyopathy? Insights from IMPROVE-HCM
Modulating energy metabolism to treat non-obstructive hypertrophic cardiomyopathy? Insights from IMPROVE-HCM
Hypertrophic cardiomyopathy (HCM) is the most common genetic heart disease worldwide and may present with or without dynam...
The many faces of SCN5A pathogenic variants: from channelopathy to cardiomyopathy
The many faces of SCN5A pathogenic variants: from channelopathy to cardiomyopathy
The SCN5A gene encodes the alpha subunit of the cardiac sodium channel, which plays a fundamental role in the generation a...
Changing the paradigm in heart failure: shifting from treatment to prevention
Changing the paradigm in heart failure: shifting from treatment to prevention
Heart failure (HF) poses a major global health challenge with rising prevalence, significant morbidity and mortality, and ...
Beyond weight loss: the potential of glucagon-like peptide-1 receptor agonists for treating heart failure with preserved ejection fraction
Beyond weight loss: the potential of glucagon-like peptide-1 receptor agonists for treating heart failure with preserved ejection fraction
Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous syndrome with various phenotypes, and obesity is...
BNP and NT-proBNP as prognostic biomarkers for the prediction of adverse outcomes in HFpEF patients: A systematic review and meta-analysis
BNP and NT-proBNP as prognostic biomarkers for the prediction of adverse outcomes in HFpEF patients: A systematic review and meta-analysis
Heart failure with preserved ejection fraction (HFpEF) presents a challenge in clinical practice due to its complexity and...
The role of coronary microcirculation in heart failure with preserved ejection fraction: An unceasing odyssey
The role of coronary microcirculation in heart failure with preserved ejection fraction: An unceasing odyssey
Heart failure with preserved ejection fraction (HFpEF) represents an entity with complex pathophysiologic pathways, among ...
Budget impact analyses for treatment of heart failure. A systematic review
Budget impact analyses for treatment of heart failure. A systematic review
Heart failure (HF) is increasing globally and turning out to be a serious worldwide public health problem with significant...
Abnormal phosphorylation / dephosphorylation and Ca2+ dysfunction in heart failure
Abnormal phosphorylation / dephosphorylation and Ca2+ dysfunction in heart failure
Heart failure (HF) can be caused by a variety of causes characterized by abnormal myocardial systole and diastole. Ca2+ cu...
New perspectives in the echocardiographic hemodynamics multiparametric assessment of patients with heart failure
New perspectives in the echocardiographic hemodynamics multiparametric assessment of patients with heart failure
International Guidelines consider left ventricular ejection fraction (LVEF) as an important parameter to categorize patien...
Current status and future directions in pediatric ventricular assist device
Current status and future directions in pediatric ventricular assist device
A ventricular assist device (VAD) is a form of mechanical circulatory support that uses a mechanical pump to partially or ...
Comparative analysis of treatment options for chronic heart failure and depression: a systematic review and Bayesian network meta-analysis
Comparative analysis of treatment options for chronic heart failure and depression: a systematic review and Bayesian network meta-analysis
Different interventions have been evaluated for the treatment of depression in heart failure (HF) patients. However, clear...
Resistance is not futile: a systematic review of the benefits, mechanisms and safety of resistance training in people with heart failure
Resistance is not futile: a systematic review of the benefits, mechanisms and safety of resistance training in people with heart failure
Exercise offers many physical and health benefits to people with heart failure (CHF), but aerobic training (AT) predominat...
Assessment of patient-reported outcomes measures in heart failure: a systematic review
Assessment of patient-reported outcomes measures in heart failure: a systematic review
Heart failure (HF) is a prevalent global disease, particularly impacting developed countries. With the world’s aging...
Latest pharmaceutical approaches across the spectrum of heart failure
Latest pharmaceutical approaches across the spectrum of heart failure
Despite major advances in prevention and medical therapy, heart failure (HF) remains associated with high morbidi...
Heart failure with mildly reduced and preserved ejection fraction: A review of disease burden and remaining unmet medical needs within a new treatment landscape
Heart failure with mildly reduced and preserved ejection fraction: A review of disease burden and remaining unmet medical needs within a new treatment landscape
This review provides a comprehensive overview of heart failure with mildly reduced and preserved ejection fraction (HFmrEF...
Incremental diagnostic and prognostic utility of left atrial deformation in heart failure using speckle tracking echocardiography
Incremental diagnostic and prognostic utility of left atrial deformation in heart failure using speckle tracking echocardiography
Left atrium (LA) is a very important component of cardiovascular performance. The assessment of LA function has gathered t...
Cardiac contractility modulation in patients with heart failure — A review of the literature
Cardiac contractility modulation in patients with heart failure — A review of the literature
Experimental in vivo and in vitro studies showed that electric currents applied during the absolute refractory period can ...
Disease features and management of cardiomyopathies in women
Disease features and management of cardiomyopathies in women
Over the last years, there has been a growing interest in the clinical manifestations and outcomes of cardiomyopathies in ...
Durable ventricular assist device in adult patients with single ventricle: a systematic literature review
Durable ventricular assist device in adult patients with single ventricle: a systematic literature review
The worldwide experience with mechanical circulatory support in adult patients with single ventricle and Fontan palliation...
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