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Targeting the insulin-like growth factor-1 receptor to overcome imatinib resistance in chronic myeloid leukemia
Targeting the insulin-like growth factor-1 receptor to overcome imatinib resistance in chronic myeloid leukemia
Patients with chronic myeloid leukemia (CML) frequently develop resistance to tyrosine kinase inhibitors such as imatinib....
Nuclear receptor profiling for subtype classification and as prognostic markers in 33 cancer types
Nuclear receptor profiling for subtype classification and as prognostic markers in 33 cancer types
Nuclear receptors, a group of 48 transcription factors that regulate a multitude of processes within our body, have long b...
JAK2 inactivating mutations promotes endometrial cancer progression by targeting HIF-1α
JAK2 inactivating mutations promotes endometrial cancer progression by targeting HIF-1α
Endometrial cancer (EC) is the ninth most common malignancy among women. While mutations in JAK2 are frequently observed i...
ADAMTS12 serves as a novel prognostic biomarker and promotes proliferation and invasion in gastric cancer
ADAMTS12 serves as a novel prognostic biomarker and promotes proliferation and invasion in gastric cancer
Gastric cancer (GC) remains a prevalent and aggressive malignancy with a poor prognosis. This study aimed to identify diag...
The PARPscore system using poly (ADP-ribose) polymerase (PARP) family features and tumor immune microenvironment in glioma
The PARPscore system using poly (ADP-ribose) polymerase (PARP) family features and tumor immune microenvironment in glioma
The immune response plays a pivotal role in tumor progression and therapy. However, the influence of protein PAR polymeras...
Global research on nanomaterials for liver cancer from 2004 to 2023: a bibliometric and visual analysis
Global research on nanomaterials for liver cancer from 2004 to 2023: a bibliometric and visual analysis
Primary liver cancer, particularly hepatocellular carcinoma, is one of the most common gastrointestinal cancers. An increa...
The role of KRT18 in lung adenocarcinoma development: integrative bioinformatics and experimental validation
The role of KRT18 in lung adenocarcinoma development: integrative bioinformatics and experimental validation
Lung adenocarcinoma (LUAD) represents one of the most common subtypes of lung cancer with high rates of incidence and mort...
The role of autophagy related 12 (ATG12) in the progression of hepatocellular carcinoma and its prognostic value
The role of autophagy related 12 (ATG12) in the progression of hepatocellular carcinoma and its prognostic value
The aim of our research was to explore the character of autophagy related 12 (ATG12) in the development of hepatocellular ...
Radiomic nomograms in CT diagnosis of gall bladder carcinoma: a narrative review
Radiomic nomograms in CT diagnosis of gall bladder carcinoma: a narrative review
Radiomics is a method that extracts many features from medical images using various algorithms. Medical nomograms are grap...
A novel histone acetylation-associated gene signature with prognostic value in Ewing sarcoma
A novel histone acetylation-associated gene signature with prognostic value in Ewing sarcoma
Histone acetylation is an important epigenetic modification, modulating the development of many tumors. However, the funct...
Identification of biomarkers for chronic lymphocytic leukemia risk: a proteome-wide Mendelian randomization study
Identification of biomarkers for chronic lymphocytic leukemia risk: a proteome-wide Mendelian randomization study
Chronic lymphocytic leukemia (CLL) is a common hematologic malignancy. Although previous research has explored association...