SCI Abstract

search
+
Human placental models for studying viral infections
Viral infections during pregnancy represent a major threat to maternal, fetal, and neonatal health outcome, with a high ri...
Ex vivo culture models to study viral infections of the liver
Ex vivo liver culture models, particularly three-dimensional (3D) models, are vital for studying viral infections of the l...
The liver as a potential gate to the brain for encephalitic viruses
To model infection of viruses targeting the liver and the central nervous system, two-dimensional in vitro cultures rapidl...
Recent advances in animal models of lymphomagenesis caused by human γ-herpesviruses
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2025 Elsevier B.V., its licensors, an...
Molecules to spillover: how climate warming impacts mosquito-borne viruses
As climate warming continues, impacts on arboviral diseases occur at all biological scales, from molecules and cells to ec...
State-of-the-art in oncolytic virotherapy using adenoviruses other than the commonly applied adenovirus type 5
There are several treatment options available against cancer, typically including surgery, radiotherapy, chemotherapy, and...
Editorial overview: Viruses and cancer — challenges, breakthroughs, and future directions
Nicole Fischer1 is Professor and Director of the Institute of Molecular Virology and Tumorvirology in Hamburg, Germany. He...
Illuminating druggable dark matter in RNA virus replication using in situ cryo-EM
Viral proteins typically exist in the context of complex virions or in the even more complex host cells in which they repl...
Human organoid models to study coronavirus infections of the respiratory tract
The coronavirus disease 2019 (COVID-19) pandemic emphasized the need to study coronaviruses more thoroughly. Next to sever...
Editorial: Tumour Virus Research on Virus Host Interactions and Cell Transformation
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2025 Elsevier B.V., its licensors, an...
Clinical indications for host-cell DNA methylation markers in cervical screening and management of cervical intraepithelial neoplasia: A review
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2025 Elsevier B.V., its licensors, an...
Drugs and drug targets for the treatment of HPV-positive cervical cancer
Cervical cancer is primarily driven by persistent infection with high-risk human papillomavirus (HPV) strains and remains ...
Too many cooks in the kitchen: HPV driven carcinogenesis – The result of collaboration or competition?
Infection by Human Papillomaviruses accounts for the most widespread sexually transmitted infection worldwide. Clinical pr...
Regulation of epithelial growth factor receptors by the oncoprotein E5 during the HPV16 differentiation-dependent life cycle
Human papillomavirus (HPV) 16 infection initiates upon viral entry into the basal cells of the epithelium. The virus manip...
Daxx and HIRA go viral – How chromatin remodeling complexes affect DNA virus infection
Daxx and HIRA are key proteins in the host response to DNA virus infections. Daxx is involved in apoptosis, transcription ...
The oncogenic role of the NSD histone methyltransferases in head and neck and cervical cancers
Understanding the role of NSD proteins in virus-induced cancers could reveal new therapeutic strategies. Targeting NSD pro...
Fibroblasts regulate the transcriptional signature of human papillomavirus-positive keratinocytes
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2025 Elsevier B.V., its licensors, an...
The HPV101 E7 protein shares host cellular targets and biological activities with high-risk HPV16 E7
Human papillomaviruses (HPVs) are a diverse family of viruses with over 450 members that have been identified and fully se...
Polyomavirus large T antigens: Unraveling a complex interactome
All members of the polyomavirus family encode a large T antigen (LT) protein that plays essential roles in viral DNA repli...
Analysis of the progression of cervical cancer in a low-and-middle-income country: From pre-malignancy to invasive disease
To better understand cervical cancer progression, we analyzed RNA from 262 biopsies from women referred for colposcopy. We...
Intraperitoneal delivery of cannabidiol (CBD) and Δ9-tetrahydocannabinol (THC) promotes papillomavirus infections in athymic nude mice
We used our mouse papillomavirus (MmuPV1) model to test the hypothesis that two primary psychoactive ingredients of mariju...
Rapid-onset cancer
4-NQO4-Nitroquinoline 1-oxideWNTWingless-related integration siteAPCAdenomatous Polyposis ColiPI3KPhosphatidylinositol 3 K...
How can HPV E6 manipulate host cell differentiation process to maintain the reservoir of infection
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2025 Elsevier B.V., its licensors, an...
De-regulation of aurora kinases by oncogenic HPV; implications in cancer development and treatment
Human papillomaviruses (HPVs) cause diseases ranging from benign warts to invasive cancers. HPVs are the cause of almost a...
The adenoviral E4orf4 protein: A multifunctional protein serving as a guide for treating cancer, a multifactorial disease
Viruses exploit several cellular pathways to support their replication, and many of these virus-targeted pathways are also...
Drosophila model of HPV18-Induced pathogenesis reveals a role for E6 oncogene in regulation of NF-κB and Wnt to inhibit apoptosis
Cancers caused by high-risk human papillomavirus (HPV) remain a significant health threat resulting in more than 300,000 d...
Evaluating the performance of the Xpert HPV assay in detecting HPV positive cases in Morocco
Recently, the World Health Organization recommended integrating HPV testing into cervical cancer screening programs global...
Clinical performance of the SureX PCR HPV test versus hybrid capture assays (DH2/careHPV) in primary cervical cancer screening
BackgroundEvaluating novel human papillomavirus (HPV) tests in well-designed, population-based screening studies is essent...
Detection of Immunoglobulin G and/or IgM antibodies specific for Lassa virus among HIV patients in the Northwestern region of Cameroon
Detection of Immunoglobulin G and/or IgM antibodies specific for Lassa virus among HIV patients in the Northwestern region of Cameroon
Persons with HIV are prone to other infections. Lassa virus (LASV)coinfection with HIV is a public health concern. Viral h...
Fulminant hepatitis and multi-organ failure following varicella zoster virus infection in an adult with G6PD deficiency: a case report
Fulminant hepatitis and multi-organ failure following varicella zoster virus infection in an adult with G6PD deficiency: a case report
Varicella zoster virus (VZV) infection in adults can lead to severe complications, particularly in those with underlying c...
Load More
format_indent_increase