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Ectopic expression of murine CD163 enables cell-culture isolation of lactate dehydrogenase-elevating virus 63 years after its discovery
ABSTRACTArteriviruses are RNA viruses related to coronaviruses but have not yet been associated with human infection. A mu...
Journal Of Virology
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Palmitoylation of the hemagglutinin of influenza B virus by ER-localized DHHC enzymes 1, 2, 4, and 6 is required for efficient virus replication
ABSTRACT Covalent attachment of the fatty acid palmitate or stearate to the cytoplasmic domain of viral glycoproteins is o...
Journal Of Virology
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A viral protein targets mitochondria and chloroplasts by subverting general import pathways and specific receptors
ABSTRACT Dual targeting is a relatively little explored phenomenon by which some proteins are transported to two different...
Journal Of Virology
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Chimeric virus-like particles of human norovirus constructed by structure-guided epitope grafting elicit cross-reactive immunity against both GI.1 and GII.4 genotypes
ABSTRACT Human norovirus (HuNoV) is the main cause of acute non-bacterial gastroenteritis worldwide. There is no vaccine c...
Journal Of Virology
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A single polymorphic residue in humans underlies species-specific restriction of HSV-1 by the antiviral protein MxB
ABSTRACT Myxovirus resistance proteins A and B (MxA and MxB) are interferon-induced proteins that exert antiviral activity...
Journal Of Virology
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Neutralizing antibodies with neurotropic factor treatment maintain neurodevelopmental gene expression upon exposure to human cytomegalovirus
ABSTRACT Human cytomegalovirus (HCMV) is a beta herpesvirus that causes severe congenital birth defects including microcep...
Journal Of Virology
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Insulin-mediated endothelin signaling is antiviral during West Nile virus infection
ABSTRACT West Nile virus (WNV) is the most prevalent mosquito-borne virus in the United States with approximately 2,000 ca...
Journal Of Virology
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N-terminal domain of classical swine fever virus Npro induces proteasomal degradation of specificity protein 1 with reduced HDAC1 expression to evade from innate immune responses
ABSTRACTClassical swine fever virus (CSFV) poses a major threat to the pig industry. The mechanisms that CSFV uses to evad...
Journal Of Virology
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Multiple mutations of SARS-CoV-2 Omicron BA.2 variant orchestrate its virological characteristics
ABSTRACT Previous studies on the Omicron BA.2 variant suggested that the virological characteristics of BA.2 are determine...
Journal Of Virology
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Kaposi’s sarcoma-associated herpesvirus glycoprotein K8.1 is critical for infection in a cell-specific manner and functions at the attachment step on keratinocytes
ABSTRACTKaposi’s sarcoma-associated herpesvirus (KSHV) is associated with Kaposi’s sarcoma and B cell malignancies. K8.1, ...
Journal Of Virology
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Tryptophan-based motifs in the LLP3 region of the HIV-1 envelope glycoprotein cytoplasmic tail direct trafficking to the endosomal recycling compartment and mediate particle incorporation
ABSTRACT The HIV-1 envelope glycoprotein complex (Env) is incorporated into developing particles at the plasma membrane (P...
Journal Of Virology
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Ubiquitin E3 ligase SPOP is a host negative regulator of enterovirus 71-encoded 2A protease
ABSTRACT The 2A protease (2Apro) encoded by enterovirus 71 (EV71) serves as an accessory protein with significant involvem...
Journal Of Virology
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Deletion of the gene for the African swine fever virus BCL-2 family member A179L increases virus uptake and apoptosis but decreases virus spread in macrophages and reduces virulence in pigs
ABSTRACT The African swine fever virus (ASFV) encodes inhibitors of innate immune responses, including type I interferon a...
Journal Of Virology
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Correction for Tejera-Hernández et al., “Mouse Adenovirus Type 1 E4orf6 Induces PKR Degradation”
American Society for Microbiology ("ASM") is committed to maintaining your confidence and trust with respect to the inform...
Journal Of Virology
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Corrected and republished from: “VP4 Is a Determinant of Alpha-Defensin Modulation of Rotaviral Infection”
ABSTRACT Fecal-oral pathogens encounter constitutively expressed enteric alpha-defensins in the intestine during replicati...
Journal Of Virology
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Erratum for Bach et al., “Regulation of VP30-Dependent Transcription by RNA Sequence and Structure in the Genomic Ebola Virus Promoter”
American Society for Microbiology ("ASM") is committed to maintaining your confidence and trust with respect to the inform...
Journal Of Virology
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Correction for Hu et al., “VP4 Is a Determinant of Alpha-Defensin Modulation of Rotaviral Infection”
American Society for Microbiology ("ASM") is committed to maintaining your confidence and trust with respect to the inform...
Journal Of Virology
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Activation of AIM2 by hepatitis B virus results in antiviral immunity that suppresses hepatitis C virus during coinfection
ABSTRACT Hepatitis B virus (HBV) infection in immunocompetent adults is mostly self-limiting, whereas Hepatitis C virus (H...
Journal Of Virology
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Extragenic suppression of an HSV-1 UL34 nuclear egress mutant reveals role for pUS9 as an inhibitor of epithelial cell-to-cell spread
ABSTRACT The herpes simplex virus pUL34 component of the nuclear egress complex functions in both nuclear egress and cell-...
Journal Of Virology
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HCMV UL8 interaction with β-catenin and DVL2 regulates viral reactivation in CD34+ hematopoietic progenitor cells
ABSTRACT Human cytomegalovirus (HCMV) is a species-specific virus that establishes a persistent/latent infection in CD34+ ...
Journal Of Virology
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Soluble CD4 and low molecular weight CD4-mimetic compounds sensitize cells to be killed by anti-HIV cytotoxic immunoconjugates
ABSTRACT The reservoir of HIV-infected cells that persist in the face of effective anti-retroviral therapy (ART) is the ba...
Journal Of Virology
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EGR1 functions as a new host restriction factor for SARS-CoV-2 to inhibit virus replication through the E3 ubiquitin ligase MARCH8
ABSTRACT Coronavirus disease 2019, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to an u...
Journal Of Virology
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N-linked glycoproteins and host proteases are involved in swine acute diarrhea syndrome coronavirus entry
ABSTRACTSwine acute diarrhea syndrome coronavirus (SADS-CoV) is highly pathogenic to piglets and poses a major threat to t...
Journal Of Virology
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Single-molecule-binding studies of antivirals targeting the hepatitis C virus core protein
ABSTRACT The hepatitis C virus (HCV) core protein (HCVcp) is the most highly conserved protein encoded by the HCV genome, ...
Journal Of Virology
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Interferon regulatory factor 7 modulates virus clearance and immune responses to alphavirus encephalomyelitis
ABSTRACT Central nervous system (CNS) infection with Sindbis virus (SINV), the prototypic alphavirus, results in encephalo...
Journal Of Virology
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Transcriptome screening identifies TIPARP as an antiviral host factor against the Getah virus
ABSTRACT Alphaviruses are emerging and re-emerging viruses that cause severe disease and threaten public health worldwide....
Journal Of Virology
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Signal peptide and N-glycosylation of N-terminal-CD2v determine the hemadsorption of African swine fever virus
ABSTRACTAfrican swine fever virus (ASFV) is the cause of African swine fever (ASF), a devastating disease that affects dom...
Journal Of Virology
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Electron microscopy mapping of the DNA-binding sites of monomeric, dimeric, and multimeric KSHV RTA protein
ABSTRACT Molecular interactions between viral DNA and viral-encoded protein are a prerequisite for successful herpesvirus ...
Journal Of Virology
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Molecular characterization of the 2022 Sudan virus disease outbreak in Uganda
ABSTRACT Uganda experienced five Ebola disease outbreaks caused by Bundibugyo virus (n = 1) and Sudan virus (SUDV) (n = 4)...
Journal Of Virology
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Herpes simplex virus 1 immediate early transcription initiation, pause-release, elongation, and termination in the presence and absence of ICP4
ABSTRACT Herpes simplex virus 1 (HSV-1) transcription is tightly regulated in a temporal cascade, utilizing cellular RNA p...
Journal Of Virology
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