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Human placental models for studying viral infections
Viral infections during pregnancy represent a major threat to maternal, fetal, and neonatal health outcome, with a high ri...
Ex vivo culture models to study viral infections of the liver
Ex vivo liver culture models, particularly three-dimensional (3D) models, are vital for studying viral infections of the l...
The liver as a potential gate to the brain for encephalitic viruses
To model infection of viruses targeting the liver and the central nervous system, two-dimensional in vitro cultures rapidl...
Recent advances in animal models of lymphomagenesis caused by human γ-herpesviruses
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2025 Elsevier B.V., its licensors, an...
Molecules to spillover: how climate warming impacts mosquito-borne viruses
As climate warming continues, impacts on arboviral diseases occur at all biological scales, from molecules and cells to ec...
State-of-the-art in oncolytic virotherapy using adenoviruses other than the commonly applied adenovirus type 5
There are several treatment options available against cancer, typically including surgery, radiotherapy, chemotherapy, and...
Editorial overview: Viruses and cancer — challenges, breakthroughs, and future directions
Nicole Fischer1 is Professor and Director of the Institute of Molecular Virology and Tumorvirology in Hamburg, Germany. He...
Illuminating druggable dark matter in RNA virus replication using in situ cryo-EM
Viral proteins typically exist in the context of complex virions or in the even more complex host cells in which they repl...
Human organoid models to study coronavirus infections of the respiratory tract
The coronavirus disease 2019 (COVID-19) pandemic emphasized the need to study coronaviruses more thoroughly. Next to sever...
Advancing zoonotic respiratory virus research through the use of organoids
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Host–pathogen interactions of emerging zoonotic viruses: bats, humans and filoviruses
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Blood virome research in myalgic encephalomyelitis/chronic fatigue syndrome: challenges and opportunities
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Epstein–Barr virus lytic replication and cancer
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Tissue-resident memory T cells in protective immunity to influenza virus
Tissue-resident memory T cells in protective immunity to influenza virus
Influenza virus is an important human pathogen with significant pandemic potential. Tissue-resident memory T cells (Trm) i...
Mechanisms of mucosal immunity at the female reproductive tract involved in defense against HIV infection
Mechanisms of mucosal immunity at the female reproductive tract involved in defense against HIV infection
Human immunodeficiency virus-1 remains a major global health threat. Since the virus is often transmitted through sexual i...
A complex immune communication between eicosanoids and pulmonary macrophages
A complex immune communication between eicosanoids and pulmonary macrophages
It has been almost 90 years since the initial discovery of prostaglandins and 60 years since establishing the link between...
Journey of monocytes and macrophages upon influenza A virus infection
Journey of monocytes and macrophages upon influenza A virus infection
Influenza viruses are enveloped, single-stranded, negative-sense RNA viruses belonging to the Orthomyxoviridae family. Inf...
Inhaled aerosol viral-vectored vaccines against tuberculosis
Inhaled aerosol viral-vectored vaccines against tuberculosis
Bacille Calmette-Guérin (BCG) remains the sole licensed vaccine against tuberculosis (TB), despite its variable efficacy i...
The natural virome and pandemic potential: Disease X
The natural virome and pandemic potential: Disease X
Over the last decade, the emergence of several zoonotic viruses has demonstrated that previously unknown or neglected path...
Pathogenesis of severe acute respiratory syndrome coronavirus-2 in nonhuman primates
Pathogenesis of severe acute respiratory syndrome coronavirus-2 in nonhuman primates
The continued pressure of COVID-19 on public health worldwide underlines the need for a better understanding of the mechan...
Editorial overview: The virome in health and disease (2022)
Editorial overview: The virome in health and disease (2022)
Jelle Matthijnssens Prof. Jelle Matthijnssens was appointed as assistant professor at the Rega Institute at KU Leuven, Bel...
Transmission of severe acute respiratory syndrome coronavirus 2 from humans to animals: is there a risk of novel reservoirs?
Transmission of severe acute respiratory syndrome coronavirus 2 from humans to animals: is there a risk of novel reservoirs?
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a zoonotic virus able to infect humans and multiple nonhum...
Hepatitis-B virus: replication cycle, targets, and antiviral approaches
Hepatitis-B virus: replication cycle, targets, and antiviral approaches
Available online 10 September 2023, 101360Author links open overlay panel, , , Highlights•Hepatitis B is a major cause of ...
Genetic and pharmacological perturbation of hepatitis-C virus entry
Genetic and pharmacological perturbation of hepatitis-C virus entry
Hepatitis-C virus (HCV) chronically infects 58 million individuals worldwide with variable disease outcome. While a subfra...
Role of the viral polymerase during adaptation of influenza A viruses to new hosts
Role of the viral polymerase during adaptation of influenza A viruses to new hosts
As a group, influenza-A viruses (IAV) infect a wide range of animal hosts, however, they are constrained to infecting sele...
Editorial overview: Viruses and Cancer
Editorial overview: Viruses and Cancer
Volume 62, October 2023, 101364Author links open overlay panelEthel Cesarman, Jennifer TotonchyShow morePrevious article i...
The role of nuclear pores and importins for herpes simplex virus infection
The role of nuclear pores and importins for herpes simplex virus infection
Microtubule transport and nuclear import are functionally connected, and the nuclear pore complex (NPC) can interact with ...
The more the merrier? Gene duplications in the coevolution of primate lentiviruses with their hosts
The more the merrier? Gene duplications in the coevolution of primate lentiviruses with their hosts
Gene duplications are a major source of genetic diversity and evolutionary innovation. Newly formed, duplicated genes can ...
Antigenic evolution of SARS coronavirus 2
Antigenic evolution of SARS coronavirus 2
SARS coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, emerged in China in December 2019. Vaccines developed we...
Improvement of mucosal immunity by a live-attenuated SARS-CoV-2 nasal vaccine
Improvement of mucosal immunity by a live-attenuated SARS-CoV-2 nasal vaccine
The effectiveness of early COVID-19 vaccines in reducing the severity of the disease has led to a focus on developing next...
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