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Structural Studies of Ion Channels: Achievements, Problems, and Perspectives
Structural Studies of Ion Channels: Achievements, Problems, and Perspectives
The superfamily of membrane proteins known as P-loop channels encompasses potassium, sodium, and calcium channels, as well...
Lipid-Mediated Adaptation of Proteins and Peptides in Cell Membranes
Lipid-Mediated Adaptation of Proteins and Peptides in Cell Membranes
The paper overviews the results of computational studies of the molecular mechanisms underlying the adaptation of model ce...
Alterations of Store-Operated Calcium Entry in Neurodegenerative Pathologies: History, Facts, and Prospects
Alterations of Store-Operated Calcium Entry in Neurodegenerative Pathologies: History, Facts, and Prospects
Neurodegenerative diseases, along with cardiovascular and oncological pathologies, are one of the most acute problems of m...
Mechanisms of Lipid-Mediated Regulation of the Pore-Forming Activity of Antimicrobial Agents: Studies on Planar Lipid Bilayers
Mechanisms of Lipid-Mediated Regulation of the Pore-Forming Activity of Antimicrobial Agents: Studies on Planar Lipid Bilayers
Planar lipid bilayers are unique tools designed for modeling cell membranes and electrophysiological studies of ion channe...
Structure and Functions of the OTOP1 Proton Channel
Structure and Functions of the OTOP1 Proton Channel
OTOP1 belongs to the otopetrin family of membrane proteins that form proton channels in cells of diverse types. In mammals...
Evolutionary Choice between Cholesterol and Ergosterol
Evolutionary Choice between Cholesterol and Ergosterol
Sterol biosynthesis has evolved early in the history of eukaryotes. In most animals, as well as in primitive fungi, the ma...
Membrane-Dependent Reactions of Blood Coagulation: Classical View and State-of-the-Art Concepts
Membrane-Dependent Reactions of Blood Coagulation: Classical View and State-of-the-Art Concepts
The complex mechanism called hemostasis evolved in living organisms to prevent blood loss when a blood vessel is damaged. ...
Cell Membrane Cholesterol and Regulation of Cellular Processes: New and the Same Old Thing
Cell Membrane Cholesterol and Regulation of Cellular Processes: New and the Same Old Thing
Membranes of living cells, or biological membranes, are unique molecular systems in which the functioning of all molecules...
Role of Membrane H+ Transport and Plasmalemma Excitability in Pattern Formation, Long-Distance Transport and Photosynthesis of Characean Algae
Role of Membrane H+ Transport and Plasmalemma Excitability in Pattern Formation, Long-Distance Transport and Photosynthesis of Characean Algae
Illuminated giant cells of Characeae produce alternating areas with H+-pump activity and zones of high H+/OH– conduc...
Nexus between RNA conformational dynamics and functional versatility
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Empowering the molecular ruler techniques with unnatural base pair system to explore conformational dynamics of flaviviral RNAs
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Conformational penalties: New insights into nucleic acid recognition
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Using residue interaction networks to understand protein function and evolution and to engineer new proteins
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Engineering the native ensemble to tune protein function: Diverse mutational strategies and interlinked molecular mechanisms
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Deep learning for intrinsically disordered proteins: From improved predictions to deciphering conformational ensembles
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Biochemistry and genetics are coming together to improve our understanding of genotype to phenotype relationships
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Characterizing heterogeneity in amyloid formation processes
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Non-canonical amino acids for site-directed spin labeling of membrane proteins
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Characterizing protein-protein interactions with thermal proteome profiling
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Retraction notice to “Liquid-EM goes viral – visualizing structure and dynamics” [Curr Opin Struct Biol 75 (August 2022) 102426]
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Editorial overview: Protein networks in health and disease
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On the emergence of machine-learning methods in bottom-up coarse-graining
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Protein-nucleic acid complexes: Docking and binding affinity
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Protein data bank: From two epidemics to the global pandemic to mRNA vaccines and Paxlovid
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Binding mechanisms of intrinsically disordered proteins: Insights from experimental studies and structural predictions
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Editorial overview: 3D Genome Chromatin organization and regulation
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Editorial overview: New perspectives on the structure and dynamics of protein-nucleic acid interactions
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Advances in structure-based allosteric drug design
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Knowledge of NUMTs and mitochondrial DNA specific primer designing is of utmost importance to avoid misidentification of heteroplasmic mutations
Knowledge of NUMTs and mitochondrial DNA specific primer designing is of utmost importance to avoid misidentification of heteroplasmic mutations
NUMTs (Nuclear DNA sequences of mitochondrial origin) are regions of mitochondrial DNA (mtDNA), integrated into the nuclea...
Yield loss and growth-defense trade-offs: impact of engineering amino acid transporters
Yield loss and growth-defense trade-offs: impact of engineering amino acid transporters
Recent studies recognize the importance of membrane transporters as vital targets for global food security, with amino aci...
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