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TAM-associated CASQ1 mutants diminish intracellular Ca content and interfere with regulation of SOCE
TAM-associated CASQ1 mutants diminish intracellular Ca content and interfere with regulation of SOCE
Tubular aggregate myopathy (TAM) is a rare myopathy characterized by muscle weakness and myalgia. Muscle fibers from TAM p...
Muscle spindle receptors and their impact on Parkinson´s disease and Cerebral Palsy subjects
Muscle spindle receptors and their impact on Parkinson´s disease and Cerebral Palsy subjects
In some neurological conditions, like Parkinson’s disease (PD) and Cerebral Palsy (CP), as well as with ageing, musc...
Enduring effects of acute prenatal ischemia in rat soleus muscle, and protective role of erythropoietin
Enduring effects of acute prenatal ischemia in rat soleus muscle, and protective role of erythropoietin
Motor disorders are considered to originate mainly from brain lesions. Placental dysfunction or maternal exposure to a per...
Rbm24-mediated post-transcriptional regulation of skeletal and cardiac muscle development, function and regeneration
Rbm24-mediated post-transcriptional regulation of skeletal and cardiac muscle development, function and regeneration
RNA-binding proteins are critically involved in the post-transcriptional control of gene expression during embryonic devel...
Numb family proteins play roles in Desmin and Vimentin localization at the Z-disc
Numb family proteins play roles in Desmin and Vimentin localization at the Z-disc
Desmin and Vimentin are major intermediate filaments at the Z-disc and play significant roles in sarcomere architecture an...
The role of MEGF10 in myoblast fusion and hypertrophic response to overload of skeletal muscle
The role of MEGF10 in myoblast fusion and hypertrophic response to overload of skeletal muscle
Biallelic mutations in multiple EGF domain protein 10 (MEGF10) gene cause EMARDD (early myopathy, areflexia, respiratory d...
Differential impact of substrates on myosin heavy and light chain expression in human stem cell-derived cardiomyocytes at single-cell level
Differential impact of substrates on myosin heavy and light chain expression in human stem cell-derived cardiomyocytes at single-cell level
To fully exploit the potential of human pluripotent stem cell-derived cardiomyocytes, ideally they should acquire a mature...
Fluorescence lifetime imaging microscopy of endogenous fluorophores in health and disease
Fluorescence lifetime imaging microscopy of endogenous fluorophores in health and disease
Fluorescence Lifetime Imaging Microscopy (FLIM) of endogenous fluorophores has recently emerged as a powerful, marker-free...
Plasticity in leukocyte migration during haematopoiesis and inflammation
Plasticity in leukocyte migration during haematopoiesis and inflammation
Under normal physiological conditions, leukocytes and other tissue resident immune cells have been shown to migrate using ...
The influences of ARHGEF9 on myoblasts migration and differentiation
The influences of ARHGEF9 on myoblasts migration and differentiation
Rho guanine nucleotide exchange factor 9 (ARHGEF9), as a protein that assists small GTPases, is widely present in various ...
RNA-seq and ChIP-seq unveils thyroid hormone receptor α deficiency affects skeletal muscle myoblast proliferation and differentiation via Col6a1 during aging
RNA-seq and ChIP-seq unveils thyroid hormone receptor α deficiency affects skeletal muscle myoblast proliferation and differentiation via Col6a1 during aging
Primary sarcopenia, an age-related syndrome, is a serious threat to the health and longevity of the elderly. Our prior stu...
miR-2400 promotes proliferation of bovine skeletal muscle-derived satellite cells by regulating MAGED1 genes expression
miR-2400 promotes proliferation of bovine skeletal muscle-derived satellite cells by regulating MAGED1 genes expression
microRNAs play a crucial role in the intricate process of muscle satellite cells proliferation and differentiation. Previo...
Insights into human muscle biology from human primary skeletal muscle cell culture
Insights into human muscle biology from human primary skeletal muscle cell culture
This review arises from the symposium held in honour of Prof Jenny Morgan at UCL in 2024 and the authors would like to ack...
Methylglyoxal reduces resistance exercise-induced protein synthesis and anabolic signaling in rat tibialis anterior muscle
Methylglyoxal reduces resistance exercise-induced protein synthesis and anabolic signaling in rat tibialis anterior muscle
Resistance exercise provides significant benefits to skeletal muscle, including hypertrophy and metabolic enhancements, su...
TAM-associated CASQ1 mutants diminish intracellular Ca2+ content and interfere with regulation of SOCE
TAM-associated CASQ1 mutants diminish intracellular Ca2+ content and interfere with regulation of SOCE
Tubular aggregate myopathy (TAM) is a rare myopathy characterized by muscle weakness and myalgia. Muscle fibers from TAM p...
Inhibition of the ubiquitin-proteasome system reduces the abundance of pyruvate dehydrogenase kinase 1 in cultured myotubes
Inhibition of the ubiquitin-proteasome system reduces the abundance of pyruvate dehydrogenase kinase 1 in cultured myotubes
Pyruvate dehydrogenase kinase (PDK), which phosphorylates the pyruvate dehydrogenase complex, regulates glucose metabolism...
The 50th anniversary of the European Society for Muscle Research: a journey through half a century of scientific advances
The 50th anniversary of the European Society for Muscle Research: a journey through half a century of scientific advances
The European Society for Muscle Research (ESMR) started in 1971 as “European Muscle Club” in a joint initiativ...
Unraveling the bidirectional relationship between muscle inflammation and satellite cells activity: influencing factors and insights
Unraveling the bidirectional relationship between muscle inflammation and satellite cells activity: influencing factors and insights
Inflammation stands as a vital and innate function of the immune system, essential for maintaining physiological homeostas...
Biomechanical evaluation of flash-frozen and cryo-sectioned papillary muscle samples by using sinusoidal analysis: cross-bridge kinetics and the effect of partial Ca2+ activation
Biomechanical evaluation of flash-frozen and cryo-sectioned papillary muscle samples by using sinusoidal analysis: cross-bridge kinetics and the effect of partial Ca2+ activation
We examined the integrity of flash-frozen and cryo-sectioned cardiac muscle preparations (introduced by Feng and Jin, 2020...
Arginine ingestion inhibits phagocyte invasion in eccentrically contracted rat fast-twitch muscle
Arginine ingestion inhibits phagocyte invasion in eccentrically contracted rat fast-twitch muscle
Eccentric contraction (ECC) has been shown to induce leukocyte invasion into skeletal muscle, resulting in muscle inflamma...
Validation of a novel western blot assay to monitor patterns and levels of alpha dystroglycan in skeletal muscle of patients with limb girdle muscular dystrophies
Validation of a novel western blot assay to monitor patterns and levels of alpha dystroglycan in skeletal muscle of patients with limb girdle muscular dystrophies
The cell membrane protein, dystroglycan, plays a crucial role in connecting the cytoskeleton of a variety of mammalian cel...
ANKRD1 expression is aberrantly upregulated in the mdm mouse model of muscular dystrophy and induced by stretch through NFκB
ANKRD1 expression is aberrantly upregulated in the mdm mouse model of muscular dystrophy and induced by stretch through NFκB
The muscular dystrophy with myositis (mdm) mouse model results in a severe muscular dystrophy due to an 83-amino-acid dele...
AMPK and glucose deprivation exert an isoform-specific effect on the expression of Na+,K+-ATPase subunits in cultured myotubes
AMPK and glucose deprivation exert an isoform-specific effect on the expression of Na+,K+-ATPase subunits in cultured myotubes
In skeletal muscle, Na+,K+-ATPase (NKA), a heterodimeric (α/β) P-type ATPase, has an essential role in maintenan...
Danicamtiv affected isometric force and cross-bridge kinetics similarly in skinned myocardial strips from male and female rats
Danicamtiv affected isometric force and cross-bridge kinetics similarly in skinned myocardial strips from male and female rats
Myotropes are pharmaceuticals that have recently been developed or are under investigation for the treatment of heart dise...
Four phases of a force transient emerge from a binary mechanical system
Four phases of a force transient emerge from a binary mechanical system
Accurate models of muscle contraction are important for understanding both muscle performance and the therapeutics that en...
The effects of exercise and mitochondrial transplantation alone or in combination against Doxorubicin-induced skeletal muscle atrophy
The effects of exercise and mitochondrial transplantation alone or in combination against Doxorubicin-induced skeletal muscle atrophy
Doxorubicin (DOX) is a chemotherapy drug used to treat various types of cancer, but it is associated with significant side...
IFRD2, a target of miR-2400, regulates myogenic differentiation of bovine skeletal muscle satellite cells via decreased phosphorylation of ERK1/2 proteins
IFRD2, a target of miR-2400, regulates myogenic differentiation of bovine skeletal muscle satellite cells via decreased phosphorylation of ERK1/2 proteins
The proliferation and differentiation of skeletal muscle satellite cells is a complex physiological process involving vari...
Effects of membrane cholesterol-targeting chemicals on skeletal muscle contractions evoked by direct and indirect stimulation
Effects of membrane cholesterol-targeting chemicals on skeletal muscle contractions evoked by direct and indirect stimulation
Cholesterol is one of the major components of plasma membrane, where its distribution is nonhomogeneous and it participate...
Sympathetic innervation in skeletal muscle and its role at the neuromuscular junction
Sympathetic innervation in skeletal muscle and its role at the neuromuscular junction
Neuromuscular junctions are the synapses between motor neurons and skeletal muscle fibers, which mediate voluntary muscle ...
Nitric oxide and ion channels mediate l-cysteine-induced inhibition of colonic smooth muscle contraction
Nitric oxide and ion channels mediate l-cysteine-induced inhibition of colonic smooth muscle contraction
Previous studies have suggested that l-cysteine regulates gut motility through hydrogen sulfide. However, the mechanisms i...
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