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Comparative Analysis of Cell Senescence Induced by the Chemotherapeutic Agents Doxorubicin, Cisplatin and Arsenic Trioxide in Human Myoblasts MB135
Comparative Analysis of Cell Senescence Induced by the Chemotherapeutic Agents Doxorubicin, Cisplatin and Arsenic Trioxide in Human Myoblasts MB135
Genotoxic and cytotoxic drugs, widely used in anticancer therapy, target proliferating cells and induce cell death through...
Association between Telomere Length and Geriatric Status in Centenarians
Association between Telomere Length and Geriatric Status in Centenarians
Aim: To evaluate the association between telomere length and frailty and individual geriatric syndromes in older adults. M...
Geroprotective Effect of the Mitochondrial-Targeted Antioxidant SkQBerb in a Model of the Chronological Aging of MB135 Human Myoblasts
Geroprotective Effect of the Mitochondrial-Targeted Antioxidant SkQBerb in a Model of the Chronological Aging of MB135 Human Myoblasts
Background: The field of gerontology is actively seeking senolytics and senomorphs that can influence the quantity and act...
Senolytic Drugs: Implications for Clinical Practice
Senolytic Drugs: Implications for Clinical Practice
Studying the mechanisms of aging is one of the most important goals of modern science. A significant amount of data on the...
Brain Aging
Brain Aging
Brain aging is part of the aging of the whole body, largely determining the success of general aging and the quality of li...
Patterns of Expression of the Key Genes of the BDNF System and Serotonin Receptors in the Brain of OXYS Rats in the Development of the Signs of Alzheimer’s Disease
Patterns of Expression of the Key Genes of the BDNF System and Serotonin Receptors in the Brain of OXYS Rats in the Development of the Signs of Alzheimer’s Disease
In spite of numerous studies, pathogenesis of the sporadic (not inherited) form of Alzheimer’s disease (AD) still re...
The Role of the Serotonin Pathway of Tryptophan Metabolism in the Development of Neuroinflammation in Alzheimer’s Disease
The Role of the Serotonin Pathway of Tryptophan Metabolism in the Development of Neuroinflammation in Alzheimer’s Disease
Despite the fact that more than 90% of tryptophan is metabolized via the kynurenine pathway, the serotonin pathway is of g...
Age-Related Changes and Loss of Damage Resistance of Kidney Tissue: The Role of a Decrease in the Number of Kidney Resident Progenitor Cells
Age-Related Changes and Loss of Damage Resistance of Kidney Tissue: The Role of a Decrease in the Number of Kidney Resident Progenitor Cells
Many organs undergo negative changes during aging that affect their functions and ability to regenerate. In particular, th...
Demographic Indicators of Probability Models
Demographic Indicators of Probability Models
Describing mortality dynamics using average indicators without considering variability can yield average results, impeding...
Mechanisms of Neurocognitive Adaptation during Aging Process
Mechanisms of Neurocognitive Adaptation during Aging Process
Human aging is associated with an increased risk of various geriatric syndromes, cognitive impairment being among the most...
Erratum to: Transport and Possible Outcome of Lipofuscin in Mouse Myocardium
Erratum to: Transport and Possible Outcome of Lipofuscin in Mouse Myocardium
An Erratum to this paper has been published: https://doi.org/10.1134/S2079057022310010
Effect of Physical Activity on Sleep Outcomes among Iranian Older Adults: A Cross-Sectional Study
Effect of Physical Activity on Sleep Outcomes among Iranian Older Adults: A Cross-Sectional Study
Sleep disorders have a significant impact on physical and mental health. This study was aimed to determine the effect of p...
On a New Paradigm of the Development of Neurodegenerative Diseases by the Example of Alzheimer’s Disease and Parkinson’s Disease
On a New Paradigm of the Development of Neurodegenerative Diseases by the Example of Alzheimer’s Disease and Parkinson’s Disease
The role of neuronal inflammation developing during the formation of amyloid plaques and Lewy bodies is investigated. The ...
Multidisciplinary Approach in the Treatment of Elderly and Senile Patients with Complications of Colon Cancer
Multidisciplinary Approach in the Treatment of Elderly and Senile Patients with Complications of Colon Cancer
The article presents the results of the treatment of elderly and senile patients with complications of colon cancer, in th...
Neurological Aspects of Systemic Lupus Erythematosus in Individuals with Late Ontogenetic Debut
Neurological Aspects of Systemic Lupus Erythematosus in Individuals with Late Ontogenetic Debut
The review presents the analysis of publications about the peculiarities of the manifestation of systemic lupus erythemato...
Age-Related Menopause and Carbonyl Stress
Age-Related Menopause and Carbonyl Stress
The review analyzes the published data of some studies on redox homeostasis in women with age-related physiological menopa...
Determinants of Subjective Loneliness and Quality of Life among Community-Dwelling Older Adults in Gorgan, Iran
Determinants of Subjective Loneliness and Quality of Life among Community-Dwelling Older Adults in Gorgan, Iran
The purpose of this study was to identify the determinants of, and relationship between, subjective loneliness, general he...
Neurological Complications and Consequences of the Novel Coronavirus COVID-19 Infection in Elderly and Senile Patients (Literature Review)
Neurological Complications and Consequences of the Novel Coronavirus COVID-19 Infection in Elderly and Senile Patients (Literature Review)
Based on available publications, the article systematizes information about some forms of lesions of the central nervous s...
Healthy Life Expectancy of People Over Age 65: Results of the Russian Epidemiological Study EVCALIPT
Healthy Life Expectancy of People Over Age 65: Results of the Russian Epidemiological Study EVCALIPT
The health of a population is an important indicator of the general well-being of the population, and it has its practical...
Effect on Physical Functions of Older Adults When Refraining from Going out due to COVID-19 Restrictions
Effect on Physical Functions of Older Adults When Refraining from Going out due to COVID-19 Restrictions
The study investigated the effect of refraining from going out during the coronavirus disease 2019 pandemic on physical fu...
Peculiarities of Venous Trophic Ulcers Course in Gerontoligical Patients according to Local Immunity and Morphological Manifestations
Peculiarities of Venous Trophic Ulcers Course in Gerontoligical Patients according to Local Immunity and Morphological Manifestations
As organs age morpho-functional changes of organs and tissues become pathological disrupting the quality of life and provi...
Influence of Perceived Ageism on Older Adults: Focus on Attitudes toward Young People and Life Satisfaction
Influence of Perceived Ageism on Older Adults: Focus on Attitudes toward Young People and Life Satisfaction
The world’s population is aging, and intergenerational conflicts between older adults and young people are becoming ...
Post-Retirement Employment among Iranian Older Adults: The Competition of Two Generation
Post-Retirement Employment among Iranian Older Adults: The Competition of Two Generation
This study seeks to investigate the factor influencing post-retirement employment among the Iranian older adults. The part...
COVID-19 in Lifespan: Psychological Impact between Young and Older Adults in Argentina
COVID-19 in Lifespan: Psychological Impact between Young and Older Adults in Argentina
The coronavirus pandemic has had a serious and worldwide impact. The increase in psychopathological symptomatology has aff...
On the Role of Geriatric Services in the Diagnosis and Monitoring of Outcomes of Post-Covid Syndrome (Review)
On the Role of Geriatric Services in the Diagnosis and Monitoring of Outcomes of Post-Covid Syndrome (Review)
In addition to the rapid spread of the pandemic in waves across the globe today, there is a growing problem called “...
Involvement of Elderly People in the Processes of Modern Digital Transformations
Involvement of Elderly People in the Processes of Modern Digital Transformations
The results of the sociological study “Digital Technologies for Tomsk Elderly,” conducted in Tomsk (May 2021) ...
Telerehabilitation of Post-Stroke Patients with Motor Function Disorders: A Review
Telerehabilitation of Post-Stroke Patients with Motor Function Disorders: A Review
Stroke is the main reason for disabilities of increasing geriatric population. It affects brain and motor function domains...
Intraoperative and Early Postoperative Risk Factors for the Development of Acute Cerebrovascular Accident in Elderly Patients after Coronary-Artery Bypass Grafting
Intraoperative and Early Postoperative Risk Factors for the Development of Acute Cerebrovascular Accident in Elderly Patients after Coronary-Artery Bypass Grafting
This work presents data on the problem of ischemic heart disease, surgical myocardial revascularization, as well as the ri...
Noninvasive Methods for Studying Skin with Different Morphotypes of Aging
Noninvasive Methods for Studying Skin with Different Morphotypes of Aging
The aim of this work is to estimate changes in the functional state of the microvasculature and to study the peculiarities...
Accelerated Aging as a Risk of Education Digitalization: Possibilities for Prevention
Accelerated Aging as a Risk of Education Digitalization: Possibilities for Prevention
The work is devoted to analyzing the negative effects of digitalizing education and considering the possibilities for thei...
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