Lyamzaev, K.G., Pustovidko, A.V., Simonyan, R.A., et al., Novel mitochondria-targeted antioxidants: Plastoquinone conjugated with cationic plant alkaloids berberine and palmatine, Pharm. Res., 2011, vol. 28, no. 11, pp. 2883–2895. https://doi.org/10.1007/s11095-011-0504-8

Article  CAS  PubMed  Google Scholar 

Skulachev, M.V., Antonenko, Y.N., Anisimov, V.N., et al., Mitochondrial-targeted plastoquinone derivatives. Effect on senescence and acute age-related pathologies, Curr. Drug Targets, 2011, vol. 12, no. 6, pp. 800–826. https://doi.org/10.2174/138945011795528859

Article  CAS  PubMed  Google Scholar 

Zinovkin, R.A., Romaschenko, V.P., Galkin, I.I., Zakharova, V.V., Pletjushkina, O.Y., Chernyak, B.V., et al., Role of mitochondrial reactive oxygen species in age-related inflammatory activation of endothelium, Aging, 2014, vol. 6, no. 8, pp. 661–674. https://doi.org/10.18632/aging.100685

Article  PubMed  PubMed Central  Google Scholar 

Zhang, L., Pitcher, L.E., Prahalad, V., Niedernhofer, L.J., and Robbins, P.D., Targeting cellular senescence with senotherapeutics: Senolytics and senomorphics, FEBS J., 2023, vol. 290, no. 5, pp. 1362–1383. https://doi.org/10.1111/febs.16350

Article  CAS  PubMed  Google Scholar 

He, S. and Sharpless, N.E., Senescence in health and disease, Cell, 2017, vol. 169, no. 6, pp. 1000–1011. PMID: 28575665; PMCID: PMC5643029.https://doi.org/10.1016/j.cell.2017.05.015

Article  CAS  PubMed  PubMed Central  Google Scholar 

Demaria, M., Ohtani, N., Youssef, S.A., Rodier, F., Toussaint, W., Mitchell, J.R., Laberge, R.M., Vijg, J., Van Steeg, H., Dollé, M.E., Hoeijmakers, J.H., de Bruin, A., Hara, E., and Campisi, J., An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA, Dev. Cell, 2014, vol. 31, no. 6, pp. 722–733. PMID: 25499914; PMCID: PMC4349629.https://doi.org/10.1016/j.devcel.2014.11.012

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mosteiro, L., Pantoja, C., Alcazar, N., Marión, R.M., Chondronasiou, D., Rovira, M., Fernandez-Marcos, P.J., Muñoz-Martin, M., Blanco-Aparicio, C., Pastor, J., Gómez-López, G., De Martino, A., Blasco, M.A., Abad, M., and Serrano, M., Tissue damage and senescence provide critical signals for cellular reprogramming in vivo, Science, 2016, vol. 354, no. 6315, aaf4445. PMID: 27884981.https://doi.org/10.1126/science.aaf4445

Article  CAS  PubMed  Google Scholar 

Ritschka, B., Storer, M., Mas, A., Heinzmann, F., Ortells, M.C., Morton, J.P., Sansom, O.J., Zender, L., and Keyes, W.M., The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration, Genes Dev., 2017, vol. 31, no. 2, pp. 172–183. PMID: 28143833; PMCID: PMC5322731.https://doi.org/10.1101/gad.290635.116

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hernandez-Segura, A., Brandenburg, S., and Demaria, M., Induction and validation of cellular senescence in primary human cells, J. Vis. Exp., 2018, no. 136, p. 57782. https://doi.org/10.3791/57782