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Novel CXCR4 Inhibitor CPZ1344 Inhibits the Proliferation, Migration and Angiogenesis of Glioblastoma
Novel CXCR4 Inhibitor CPZ1344 Inhibits the Proliferation, Migration and Angiogenesis of Glioblastoma
Glioblastoma (GBM) are life-threatening tumors with a poor prognosis and low cure rates. GBMs are malignant brain tumors t...
Concordance Between Biopsy and Radical Prostatectomy Gleason Scores: Evaluation of Determinants in a Large-Scale Study of Patients Undergoing RARP in Belgium
Concordance Between Biopsy and Radical Prostatectomy Gleason Scores: Evaluation of Determinants in a Large-Scale Study of Patients Undergoing RARP in Belgium
To determine whether Gleason scores were concordant between prostate biopsies (bGS) and the definitive resection specimen ...
The Ratio of ssDNA to dsDNA in Circulating Cell-Free DNA Extract is a Stable Indicator for Diagnosis of Gastric Cancer
The Ratio of ssDNA to dsDNA in Circulating Cell-Free DNA Extract is a Stable Indicator for Diagnosis of Gastric Cancer
Due to the different mechanisms of cell-free DNA production, the single-stranded DNA to double-stranded DNA ratio in blood...
Increased miR-20b Level in High Grade Cervical Intraepithelial Neoplasia
Increased miR-20b Level in High Grade Cervical Intraepithelial Neoplasia
Cervical cancer is a common malignant tumor worldwide ranking fourth in incidence and mortality among females, which was r...
Prognostic Role of Aryl Hydrocarbon Receptor Interacting Protein (AIP) Immunohistochemical Expression in Patients with Resected Gastric Carcinomas
Prognostic Role of Aryl Hydrocarbon Receptor Interacting Protein (AIP) Immunohistochemical Expression in Patients with Resected Gastric Carcinomas
Aryl hydrocarbon receptor (AHR) interacting protein (AIP) is a chaperone which binds to inactive AHR in the cell cytoplasm...
Overexpression of Long Non-Coding RNA FGF14-AS2 Inhibits Colorectal Cancer Proliferation Via the RERG/Ras/ERK Signaling by Sponging microRNA-1288-3p
Overexpression of Long Non-Coding RNA FGF14-AS2 Inhibits Colorectal Cancer Proliferation Via the RERG/Ras/ERK Signaling by Sponging microRNA-1288-3p
Colorectal cancer remains one of most common cancer types with poor prognosis globally. Recent years, numerous studies dep...
The Effect of Methylselenocysteine and Sodium Selenite Treatment on microRNA Expression in Liver Cancer Cell Lines
The Effect of Methylselenocysteine and Sodium Selenite Treatment on microRNA Expression in Liver Cancer Cell Lines
The unique character of selenium compounds, including sodium selenite and Se-methylselenocysteine (MSC), is that they exer...
The Role of Time as a Prognostic Factor in Pediatric Brain Tumors: a Multivariate Survival Analysis
The Role of Time as a Prognostic Factor in Pediatric Brain Tumors: a Multivariate Survival Analysis
There is no evidence that prolonged pre diagnostic symptomatic intervals (PSI) increases the risk of death in pediatric br...
Metabolic Parameters as Predictors for Progression Free and Overall Survival of Patients with Metastatic Colorectal Cancer
Metabolic Parameters as Predictors for Progression Free and Overall Survival of Patients with Metastatic Colorectal Cancer
We tested the prognostic relevance of metabolic parameters and their relative changes in patients with metastatic colorect...
The Clinical Impact of Re-biopsies in Lung Adenocarcinoma: a Retrospective Multicenter Study
The Clinical Impact of Re-biopsies in Lung Adenocarcinoma: a Retrospective Multicenter Study
If a patient’s cancer progresses while undergoing targeted therapy, a re-biopsy is not mandatory. But when evaluatin...
Papillary Endothelial Hyperplasia (Masson Tumor) of the Hand. Surgical and Pathological Consideration from Seven Cases Using New Vascular Markers
Papillary Endothelial Hyperplasia (Masson Tumor) of the Hand. Surgical and Pathological Consideration from Seven Cases Using New Vascular Markers
Although papillary endothelial hyperplasia may occur at almost any site, one of the most common sites is the hand. It is g...
Secreted Frizzled-Related Protein 4 (SFRP4) Is an Independent Prognostic Marker in Prostate Cancers Lacking Fusions
Secreted Frizzled-Related Protein 4 (SFRP4) Is an Independent Prognostic Marker in Prostate Cancers Lacking Fusions
Secreted frizzled-related protein 4 (SFRP4) controls WNT signaling and is thought to play a role for tumor aggressiveness....
Prognostic Role of Immune Markers in Triple Negative Breast Carcinoma
Prognostic Role of Immune Markers in Triple Negative Breast Carcinoma
Tumor immune microenvironment (TIME) is a significant prognostic parameter for triple negative breast carcinomas (TNBC) du...
Expression of , and Genes for Predicting Survival in Triple-Negative and Hormone Receptor-Positive Subtypes of Breast Cancer
Expression of , and Genes for Predicting Survival in Triple-Negative and Hormone Receptor-Positive Subtypes of Breast Cancer
Triple-negative breast cancer (TNBC) is characterized by aggressive phenotype and a poorer prognosis compared to the estro...
Examination of Tumor Regression Grading Systems in Breast Cancer Patients Who Received Neoadjuvant Therapy
Examination of Tumor Regression Grading Systems in Breast Cancer Patients Who Received Neoadjuvant Therapy
Neoadjuvant therapy is a common form of treatment in locally advanced breast cancer (LABC) patients. Besides some guidelin...
The Proportion of Tumour-Stroma in Metastatic Lymph Nodes is An Accurately Prognostic Indicator of Poor Survival for Advanced-Stage Colon Cancers
The Proportion of Tumour-Stroma in Metastatic Lymph Nodes is An Accurately Prognostic Indicator of Poor Survival for Advanced-Stage Colon Cancers
The importance of tumour microenvironment in tumour behaviour has now become clearer. This study aimed to determine the pr...
Grade I, II and III Follicular Lymphomas Express Ig V Genes with Different Patterns of Somatic Mutation
Grade I, II and III Follicular Lymphomas Express Ig V Genes with Different Patterns of Somatic Mutation
Follicular lymphoma (FL) is an indolent, B-cell, non-Hodgkin’s lymphoma with varying cytological appearance and clin...
Prevalence of and Alterations in Urachal Cancer
Prevalence of and Alterations in Urachal Cancer
Urachal carcinoma (UrC) is a rare tumor with remarkable histological and molecular similarities to colorectal cancer (CRC)...
Prognostic Significance of Lacunarity in Preoperative Biopsy of Colorectal Cancer
Prognostic Significance of Lacunarity in Preoperative Biopsy of Colorectal Cancer
The quantity and quality of preoperative material in colorectal cancer is often limiting factor in determination of risk f...
Promoter Mutation Analysis of Long-Non-coding RNA RMRP Gene in Solid Tumors
Promoter Mutation Analysis of Long-Non-coding RNA RMRP Gene in Solid Tumors
1.Rheinbay E, Parasuraman P, Grimsby J, Tiao G, Engreitz JM, Kim J, Lawrence MS, Taylor-Weiner A, Rodriguez-Cuevas S, Rose...
Label-Free Semiquantitative Liquid Chromatography-Tandem Mass Spectrometry Proteomics Analysis of Laryngeal/Hypopharyngeal Squamous Cell Carcinoma on Formalin-Fixed, Paraffin-Embedded Tissue Samples - a Pilot Study
Label-Free Semiquantitative Liquid Chromatography-Tandem Mass Spectrometry Proteomics Analysis of Laryngeal/Hypopharyngeal Squamous Cell Carcinoma on Formalin-Fixed, Paraffin-Embedded Tissue Samples - a Pilot Study
Squamous cell carcinoma (SCC) of the head and neck region is the sixth most frequent malignancy with high mortality rate. ...
Coronavirus in Hematologic Malignancies: Targeting Molecules Beyond the Angiotensin-Converting Enzyme 2 (ACE2) Wall in COVID-19
Coronavirus in Hematologic Malignancies: Targeting Molecules Beyond the Angiotensin-Converting Enzyme 2 (ACE2) Wall in COVID-19
1.Fehr AR, Perlman S (2015) Coronaviruses: an overview of their replication and pathogenesis. Methods Mol Biol 1282:1–23CA...
The Role of Immunohistochemical Overexpression of p53 as Adverse Prognostic Factor in Primary Testicular Diffuse Large B Cell Lymphoma
The Role of Immunohistochemical Overexpression of p53 as Adverse Prognostic Factor in Primary Testicular Diffuse Large B Cell Lymphoma
Conflict of Interest None of the contributing authors has a...
Total Tumor Volume Should be Considered as an Important Prognostic Factor for Synchronous Multiple Gastric Cancer Patients with Curative Gastrectomy
Total Tumor Volume Should be Considered as an Important Prognostic Factor for Synchronous Multiple Gastric Cancer Patients with Curative Gastrectomy
Synchronous multiple gastric cancer (SMGC) was a special type of gastric cancer with relatively low incidence. This articl...
Mid-Infrared Imaging Is Able to Characterize and Separate Cancer Cell Lines
Mid-Infrared Imaging Is Able to Characterize and Separate Cancer Cell Lines
Malignancies are still responsible for a large share of lethalities. Macroscopical evaluation of the surgical resection ma...
Pathology & Oncology Research
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Co-Expression of Mesothelin and CA125 Is Associated with the Poor Prognosis of Endometrial Serous Carcinoma and Mixed Carcinomas Including Serous Carcinoma
Co-Expression of Mesothelin and CA125 Is Associated with the Poor Prognosis of Endometrial Serous Carcinoma and Mixed Carcinomas Including Serous Carcinoma
The aim of this study was to investigate the association between the clinicopathologic factors and either expression or co...
Aggressive Paraganglioma of the Urinary Bladder with Local Recurrence and Pelvic Metastasis
Aggressive Paraganglioma of the Urinary Bladder with Local Recurrence and Pelvic Metastasis
Many pheochromocytoma and extra-adrenal paraganglioma are benign, but some are malignant. Pheochromocytoma of the Adrenal ...
Low Fraction Size Re-irradiation for Large Volume Recurrence of Glial Tumours
Low Fraction Size Re-irradiation for Large Volume Recurrence of Glial Tumours
The aim of the present study was to evaluate the efficacy of re-irradiation (re-RT) in patients with advanced local relaps...
Somatic Mutations and Intratumoral Heterogeneity of Cancer-Related Genes NLK, YY1 and PA2G4 in Gastric and Colorectal Cancers
Somatic Mutations and Intratumoral Heterogeneity of Cancer-Related Genes NLK, YY1 and PA2G4 in Gastric and Colorectal Cancers
Many genes act as both tumor suppressor gene (TSG) and proto-oncogene depending on cellular context and cancer type. Nemo-...
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