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Immune checkpoint inhibitor-associated sick sinus syndrome and cardiogenic shock
Immune checkpoint inhibitor-associated sick sinus syndrome and cardiogenic shock
Immune checkpoint inhibitors (ICI) represent a major advance in the treatment of cancer. Most studies of ICI have underest...
Phosphoglyceride crystal deposition with suspected malignant ovarian tumor: a case report and literature review
Phosphoglyceride crystal deposition with suspected malignant ovarian tumor: a case report and literature review
Phosphoglyceride crystal deposition disease is a rare condition occurring in soft tissues, resulting in scarring and affec...
A case of uncommon metastasis located posterior to the seminal vesicles in renal cell carcinoma
A case of uncommon metastasis located posterior to the seminal vesicles in renal cell carcinoma
Renal cell carcinoma (RCC) is known for its potential to metastasize to various sites but metastasis to the area posterior...
Reduction of bleeding by cabozantinib in metastatic renal cell carcinoma with hereditary hemorrhagic telangiectasia
Reduction of bleeding by cabozantinib in metastatic renal cell carcinoma with hereditary hemorrhagic telangiectasia
Hereditary hemorrhagic telangiectasia (HHT) is a rare genetic disorder characterized by refractory recurrent epistaxis and...
Ileal perforation at the site of peritoneal metastasis with intestinal infiltration by dual EGFR-VEGF pathway inhibition in an EGFR-mutant non-small cell lung cancer patient
Ileal perforation at the site of peritoneal metastasis with intestinal infiltration by dual EGFR-VEGF pathway inhibition in an EGFR-mutant non-small cell lung cancer patient
Gastrointestinal (GI) perforation including ileal perforation is a rare complication of antivascular endothelial growth fa...
A case of selpercatinib treatment for anaplastic thyroid carcinoma resulting in abscess formation
A case of selpercatinib treatment for anaplastic thyroid carcinoma resulting in abscess formation
Rearranged during transfection (RET) gene abnormality is a driver gene mutation that causes thyroid cancer, and selpercati...
A case of pagetoid spread of urothelial carcinoma with notable reduction achieved through enfortumab vedotin, resulting in complete surgical resection
A case of pagetoid spread of urothelial carcinoma with notable reduction achieved through enfortumab vedotin, resulting in complete surgical resection
Secondary extramammary Paget’s disease is a rare condition associated with the contiguous extension of tumor cells f...
Fertility preservation in men with hypogonadotropic hypogonadism secondary to germinoma: two cases of gonadotropin replacement therapy before induction of anticancer chemotherapy
Fertility preservation in men with hypogonadotropic hypogonadism secondary to germinoma: two cases of gonadotropin replacement therapy before induction of anticancer chemotherapy
Hypogonadotropic hypogonadism can be caused by brain tumors. For a malignancy such as a germ cell tumor, chemotherapy comb...
A pathological complete response and adrenal insufficiency in a patient with advanced renal pelvic cancer treated with pembrolizumab
A pathological complete response and adrenal insufficiency in a patient with advanced renal pelvic cancer treated with pembrolizumab
Metastatic upper tract urothelial carcinoma (mUTUC) often has poor prognosis. While systemic therapy is the standard care ...
Dermatofibrosarcoma protuberance with a unique appearance mimicking neurofibroma arising from a conventional area
Dermatofibrosarcoma protuberance with a unique appearance mimicking neurofibroma arising from a conventional area
A 21 year-old Japanese man had a rapidly growing pedunculated soft tumor in the abdomen within the past year, the...
Treatment of HER2-positive cutaneous apocrine carcinoma of the axilla
Treatment of HER2-positive cutaneous apocrine carcinoma of the axilla
Cutaneous apocrine carcinoma (CAC) is an extremely rare skin appendage malignant tumor that develops in the apocrine sweat...
SMARCA4-deficient epithelioid sarcoma revealed by comprehensive genomic profiling, leading to a notable response by nivolumab treatment
SMARCA4-deficient epithelioid sarcoma revealed by comprehensive genomic profiling, leading to a notable response by nivolumab treatment
A 50-year-old man presented with a bulky mass in the left thigh and was referred to our department. He showed an impaired ...
Prophylactic use of duloxetine hydrochloride in oxaliplatin-induced first-bite syndrome
Prophylactic use of duloxetine hydrochloride in oxaliplatin-induced first-bite syndrome
First-bite syndrome (FBS) is manifested as acute and severe pain in the parotid region occurring at the first bite of a me...
Prostate ductal adenocarcinoma with MLH1 copy number loss, microsatellite instability high and BRCA2 mutation
Prostate ductal adenocarcinoma with MLH1 copy number loss, microsatellite instability high and BRCA2 mutation
Mismatch repair deficiency (MMRd) or microsatellite instability high (MSI-H) is rare in prostate cancer and more frequentl...
Mini-open periacetabular cementoplasty for periacetabular bone metastasis: a report of two cases
Mini-open periacetabular cementoplasty for periacetabular bone metastasis: a report of two cases
Bone metastasis in the periacetabular region usually causes severe pain and functional disability. Some surgical procedure...
Foreign body granuloma caused by gauze fibers: a rare cause of chronic postoperative ileus following cytoreductive surgery for pseudomyxoma peritonei
Foreign body granuloma caused by gauze fibers: a rare cause of chronic postoperative ileus following cytoreductive surgery for pseudomyxoma peritonei
Foreign body granuloma (FBG) is an inflammatory reaction to an exogenous agent. This entity is well known on the cutaneous...
Successful osimertinib treatment for Meckel’s cave metastasis: a case report
Successful osimertinib treatment for Meckel’s cave metastasis: a case report
Osimertinib has emerged as the standard first-line treatment for advanced non-small cell lung cancer (NSCLC) with EGFR mut...
Capecitabine and oxaliplatin induced Steven–Johnson syndrome following nivolumab in a patient of metastatic esophageal carcinoma
Capecitabine and oxaliplatin induced Steven–Johnson syndrome following nivolumab in a patient of metastatic esophageal carcinoma
Stevens–Johnson syndrome presents as mucocutaneous blistering and sloughing, which may follow a devastating clinical...
Primary signet-ring cell carcinoma of the bladder treated with laparoscopic radical cystectomy: a case report
Primary signet-ring cell carcinoma of the bladder treated with laparoscopic radical cystectomy: a case report
Primary bladder adenocarcinomas comprise 0.5–2% of all epithelial bladder neoplasms. Of these, primary signet-ring c...
A challenging case of an adamantinoma of fibula with soft tissue mass harboring distinct histopathology
A challenging case of an adamantinoma of fibula with soft tissue mass harboring distinct histopathology
We present a case of adamantinoma that originated from the fibula and had a large soft tissue component measuring approxim...
A case of hereditary breast and ovarian cancer syndrome of initially presented as cancer of unknown primary with lymph node metastases unveiled by genetic analysis
A case of hereditary breast and ovarian cancer syndrome of initially presented as cancer of unknown primary with lymph node metastases unveiled by genetic analysis
Cancer of unknown primary (CUP) is a heterogeneous disease concept involving various malignant tumors. Understanding its p...
Significant reduction in burden of metastatic disease by intermittent docetaxel therapy in a patient with castration-resistant prostate cancer
Significant reduction in burden of metastatic disease by intermittent docetaxel therapy in a patient with castration-resistant prostate cancer
Intermittent docetaxel therapy (IDT) is rarely used nowadays as a treatment option for men with metastatic castration-resi...
Utility of articulating instruments as an alternative to robotic devices in laparoscopic right hemicolectomy
Utility of articulating instruments as an alternative to robotic devices in laparoscopic right hemicolectomy
Laparoscopic complete mesocolic excision with central vessel ligation has been widely accepted for its oncological benefit...
Intratumoral metastasis of sigmoid colon cancer to chromophobe renal cell carcinoma: a case report
Intratumoral metastasis of sigmoid colon cancer to chromophobe renal cell carcinoma: a case report
We herein report an extremely rare case of intratumoral metastasis of colon cancer to chromophobe renal cell carcinoma. A ...
Rapid tumor progression complicated with liver abscess in a patient with gastric cancer receiving nivolumab therapy
Rapid tumor progression complicated with liver abscess in a patient with gastric cancer receiving nivolumab therapy
Immune checkpoint inhibitors have been approved for treating various cancer types. However, several studies reported rapid...
A case of postoperative pancreatitis in patients with renal cell carcinoma with an inferior vena cava tumor thrombus treated by presurgical lenvatinib plus pembrolizumab
A case of postoperative pancreatitis in patients with renal cell carcinoma with an inferior vena cava tumor thrombus treated by presurgical lenvatinib plus pembrolizumab
Pancreatic injury is a rare, but noted complication of nephrectomy. We report a case involving a 56-year-old man who prese...
Challenges in the management of Turner syndrome with Y chromosome material: a case report of prophylactic gonadectomy revealing dysgerminoma
Challenges in the management of Turner syndrome with Y chromosome material: a case report of prophylactic gonadectomy revealing dysgerminoma
Turner syndrome (TS) patients with Y chromosome material face an increased risk of gonadal germ cell tumors (GCTs). This c...
Suction thrombectomy of a uterine carcinosarcoma tumor thrombus extending into the IVC and right atrium
Suction thrombectomy of a uterine carcinosarcoma tumor thrombus extending into the IVC and right atrium
Uterine carcinosarcoma is a rare, aggressive tumor with several cases in the literature reporting cardiac tumor thrombus i...
Durvalumab plus carboplatin-etoposide treatment in a patient with small-cell lung cancer on hemodialysis: a case report and literature review
Durvalumab plus carboplatin-etoposide treatment in a patient with small-cell lung cancer on hemodialysis: a case report and literature review
Little is known about the efficacy and safety of durvalumab plus carboplatin-etoposide treatment in patients with extensiv...
Multidisciplinary treatment for small cell carcinoma of the bladder: a case report
Multidisciplinary treatment for small cell carcinoma of the bladder: a case report
Small cell carcinoma (SCC) of the urinary bladder is a rare and highly aggressive subtype of bladder cancer. Most cases ar...
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