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Polypoid Ganglioneuroma in a Patient with Colonic Polyposis: A Case Report
Ganglioneuromas are benign tumors of the autonomic nervous system. They are rarely found in the colonic mucosa, where symp...
Investigating the Role of Escherichia coli Infection in the Pathogenesis of Bladder Cancer: A Comparative Genomics Interaction
Background: Bladder cancer (BC) is the 10th most common cancer worldwide. Microorganisms, including bacteria, may contribu...
Oridonin Enhances Radiotherapy Efficacy by Inducing Late-Stage Cell Death and G2/M Arrest in U87MG Glioma Cells
Background: Glioblastoma multiforme is a deadly brain tumor with limited treatment options. The aim of this study was to i...
Gefitinib Combination with Radiotherapy in Patients with Local Advanced Non-Small Cell Lung Cancer
Background: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors is a crucial agent in EGFR-mutated advanced...
A Dosimetric Study of Accidental Internal Mammary Lymph Node Irradiation during Locoregional Breast Irradiation
Background: One remaining grey zone in locoregional breast irradiation is whether to irradiate internal mammary lymph node...
Evaluation of the Prognostic Role of Leptin and Cyclin D1 Expression in Colorectal Cancer
Background: Colorectal cancer (CRC) is one of the most malignancies worldwide. This study aimed to determine the role of l...
The Safety and Efficacy of Cold Atmospheric Plasma as a Novel Therapy: An in vivo Study
Background: Cold atmospheric plasma (CAP) may reduce bacteria and aid wound healing through reactive oxygen species. Recen...
Comparison of Interleukin-18 Serum Levels in Patients with Breast Cancer and Idiopathic Granulomatous Mastitis
Background: Breast cancer (BC), as a global challenge, is one of the most prevalent malignant diseases among women. Idiopa...
Flaxseed Extract Can Modulates Apoptotic Genes to Promote Cell Death in Breast Cancer Cells
Background: Breast cancer is a multifactorial malignancy with uncertain treatment outcomes, making its treatment challengi...
Evaluation of Potential miR-221, miR-93, miR-21, and miR-24 as Molecular Markers for Laryngeal Squamous Cell Carcinoma
Background: Laryngeal cancer, the most prevalent head and neck malignancy, represents 2.4% of all tumors and is the 11th m...
Prevalence and Clinicopathologic Features of HER2 Overexpression in Endocervical Adenocarcinoma
Background: Endocervical adenocarcinoma (ENCA) has poor prognosis and is increasing in developing countries. Human epiderm...
Nettle (Urtica Dioica L.) Modulates Angiogenesis by Targeting the PI3K/AKT/eNOS Pathway in Prostate Cancer
Background: Medicinal plants, predominantly those rich in polyphenolic mixtures, have been recommended to have chemopreven...
Management of HER2-Low Metastatic Breast Cancer: A Comprehensive Statement by an Expert Group from the Middle East and Africa Region
Approximately 50 to 67% of breast cancers (BCs), traditionally categorized as human epidermal growth factor receptor 2 (HE...
High Expression of Myosin ⅩⅥ Predicts Poor Prognosis in Head and Neck Squamous Cell Carcinoma
Background: Myosins, a superfamily of actin-dependent molecular motors, have emerged as crucial players in tumorigenesis. ...
Ozonated Aloe Vera Oil Accelerates Radiation Dermatitis Healing in Sprague Dawley Rats
Background: Radiation dermatitis is the most common side-effect of radiation therapy. The current daily therapy uses topic...
Clinical Benefits of Metronomic Chemotherapy in Platinum-Refractory, Recurrent, and Metastatic Head and Neck Squamous Cell Carcinoma
Background: Patients with platinum-refractory disease who experience early treatment failure of head and neck squamous cel...
Lysophosphatidylcholine Acyltransferase 1 (LPCAT1): A Predictor of Acute Leukemia Prognosis
Background: Lysophosphatidylcholine acyltransferases 1 (LPCAT1) overexpression and prognostic significance have been shown...
Positive Expression of IGFBP2 as a Novel Prognostic Biomarker for Patients with Lower-Grade Gliomas
Background: Previous studies have identified insulin-like growth factor-binding protein 2 (IGFBP2) as a target gene associ...
Aberrant DNA Methylation of FTH-1 and SHOX2 Contributes to Lung Cancer Progression
Background: Lung cancer is the most lethal malignancy in the world due to its poor prognosis. DNA methylation change has b...
Cytogenetics and Molecular Abnormalities in Pediatric Patients with Acute Myeloid Leukemia in a Referral Center in Tehran, Iran
Background: Acute myeloid leukemia (AML) accounts for 15%-20% of childhood leukemia. A variety of cytogenetic abnormalitie...
Identification of Breast Cancer Biomarkers by Constructing Protein-Protein Interaction and miRNAs-mRNAs Networks
Background: In cancer-related diseases, early detection and control of disease progression are very important for successf...
Anticancer Activity of Holothuria Leucospilota-Derived Saponin on MNK45 Gastric Cancer Cell via Upregulation of CDH1 Hub Gene
Background: The treatment of gastric cancer (GC) is still quite challenging. Yet, marine invertebrates have been found to ...
The Implication of Chuang's Prognostic Scale in Metastatic Gastric Cancer
Background: Patients with metastatic gastric cancer (mGC) endure a significant symptom burden following subsequent lines o...