Document Type : Case Report(s)

Authors

1 Department of Pathology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

2 Trauma Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

10.30476/mejc.2025.103928.2158

Abstract

Ganglioneuromas are benign tumors of the autonomic nervous system. They are rarely found in the colonic mucosa, where symptoms tend to be non-specific. Some patients may present with abdominal pain, changes in bowel habits, hematochezia, ileus, or obstruction. There are few reports in the literature of ganglioneuromas coexisting with colonic polyposis or even adenocarcinoma. We report a case of a 37-year-old man with polypoid ganglioneuroma, colonic polyposis, and a family history of colon cancer, who had a favorable outcome after two years of follow-up. Ganglioneuroma is a neuroectodermal tumor that is rarely observed in the colorectal mucosa. In the case of polypoid ganglioneuroma, as seen in our patient, no syndromic associations were identified. The patient was successfully treated with endoscopic polypectomy, resulting in a favorable clinical outcome.

Highlights

Firouze Jafari (PubMed)

Keywords

Main Subjects

This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination, and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.30476/mejc.2025.103928.2158