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Efficacy and Safety of Metronomic Capecitabine in Hepatocellular Carcinoma: A Systematic Review and Meta-analysis
Efficacy and Safety of Metronomic Capecitabine in Hepatocellular Carcinoma: A Systematic Review and Meta-analysis
Metronomic capecitabine has been found to be useful in several types of cancers such as pancreatic cancer, breast cancer, ...
Role of Interleukins in Pancreatic Cancer: A Literature Review
Role of Interleukins in Pancreatic Cancer: A Literature Review
This review article summarizes the pathophysiological aspects of interleukins (ILs) including IL-1, IL-2, IL-3, IL-4, IL-5...
Endoscopic Resection of Stage T1 Colorectal Adenocarcinoma Followed by Surgical Intervention: a Single-center Retrospective Study
Endoscopic Resection of Stage T1 Colorectal Adenocarcinoma Followed by Surgical Intervention: a Single-center Retrospective Study
Domestic and international guidelines recommend endoscopic resection for stage T1 colorectal adenocarcinoma with indicatio...
Synergistic Effects of Fruquintinib Combined with Immune Checkpoint Inhibitors on Metastatic Colorectal Cancer
Synergistic Effects of Fruquintinib Combined with Immune Checkpoint Inhibitors on Metastatic Colorectal Cancer
Fruquintinib has received approval for the management of patients with chemotherapy-resistant metastatic colorectal cancer...
Primary Intrahepatic Mesothelioma: Case Series and Systematic Review of Literature
Primary Intrahepatic Mesothelioma: Case Series and Systematic Review of Literature
Primary intrahepatic mesothelioma (PIHMM) has been rarely reported. Its typical clinical presentation, radiological featur...
Colorectal Leiomyosarcoma: Demographics Patterns, Treatment Characteristics, and Survival Analysis in the U.S. Population
Colorectal Leiomyosarcoma: Demographics Patterns, Treatment Characteristics, and Survival Analysis in the U.S. Population
Colorectal leiomyosarcoma (CR-LMS) is a rare neoplasm arising from smooth muscle cells. It accounts for less than 0.1% of ...
Advanced Imaging of Hepatocellular Carcinoma: A Review of Current and Novel Techniques
Advanced Imaging of Hepatocellular Carcinoma: A Review of Current and Novel Techniques
Hepatocellular carcinoma (HCC) is the most common primary carcinoma arising from the liver. Although HCC can arise de novo...
Long-Term Survivor of Intrahepatic Cholangiocarcinoma for over 18 Years: Case Study with Longitudinal Histo-molecular and Tumor Immune Microenvironment Characterization and Systematic Review of the Literature
Long-Term Survivor of Intrahepatic Cholangiocarcinoma for over 18 Years: Case Study with Longitudinal Histo-molecular and Tumor Immune Microenvironment Characterization and Systematic Review of the Literature
Intrahepatic cholangiocarcinoma is a biliary neoplasm usually showing a dismal prognosis. In early stages, surgical resect...
Comparative Cost-Effectiveness of Gemcitabine and Cisplatin in Combination with S-1, Durvalumab, or Pembrolizumab as First-Line Triple Treatment for Advanced Biliary Tract Cancer
Comparative Cost-Effectiveness of Gemcitabine and Cisplatin in Combination with S-1, Durvalumab, or Pembrolizumab as First-Line Triple Treatment for Advanced Biliary Tract Cancer
The clinical effectiveness of triple chemotherapy consisting of gemcitabine, cisplatin plus either S-1 (GCS), durvalumab (...
Both Th1 and Th2 CD4 + T-Cell Lineage Infiltrations Decrease in Post-hematopoietic Stem Cell Transplantation Colon Adenoma
Both Th1 and Th2 CD4 + T-Cell Lineage Infiltrations Decrease in Post-hematopoietic Stem Cell Transplantation Colon Adenoma
As long-term survival improves after allogeneic hematopoietic stem cell transplantation (HSCT), the risk for secondary sol...
Anti-EGFR Rechallenge in Metastatic Colorectal Cancer and the Role of ctDNA: A Systematic Review and Meta-analysis
Anti-EGFR Rechallenge in Metastatic Colorectal Cancer and the Role of ctDNA: A Systematic Review and Meta-analysis
Metastatic colorectal cancer (mCRC) remains a significant clinical challenge. While anti-EGFR inhibitors have improved sur...
A Phase 2 study of Savolitinib in Patients with MET Amplified Metastatic Colorectal Cancer
A Phase 2 study of Savolitinib in Patients with MET Amplified Metastatic Colorectal Cancer
MET amplification (amp) is a driver of acquired resistance to epidermal growth factor receptor (EGFR) antibodies in patien...
Delayed Surgery after Neoadjuvant Short-course Radiation for Rectal Cancer Improves Pathologic Outcomes without Impacting Survival: A National Cancer Database Analysis
Delayed Surgery after Neoadjuvant Short-course Radiation for Rectal Cancer Improves Pathologic Outcomes without Impacting Survival: A National Cancer Database Analysis
Interval to surgery following short course radiotherapy (SCRT) for rectal cancer is not standardized. This study investiga...
The Association Between Patient-Reported Outcomes and Surgical Attrition During Neoadjuvant Therapy for Gastrointestinal Malignancies
The Association Between Patient-Reported Outcomes and Surgical Attrition During Neoadjuvant Therapy for Gastrointestinal Malignancies
Neoadjuvant therapy (NT) is increasingly used for gastrointestinal (GI) and hepatopancreatobiliary (HPB) cancers. Risk fac...
Predictors of Understaging with EUS and PET-CECT in Early Esophageal Carcinoma
Predictors of Understaging with EUS and PET-CECT in Early Esophageal Carcinoma
The clinicoradiological staging for esophageal cancer is fraught with variable accuracy, potentially depriving patients wh...
Demographics, Prognostic Factors, and Survival Outcomes in Hepatic Angiosarcoma: A Retrospective Analysis
Demographics, Prognostic Factors, and Survival Outcomes in Hepatic Angiosarcoma: A Retrospective Analysis
Hepatic angiosarcoma (HA) is a rare malignant vascular neoplasm. Currently, there are no standardized protocols for treati...
Gender, Race, and Regional Disparities in Leading Authorships of Gastroenterology and Hepatology Randomized Controlled Trials
Gender, Race, and Regional Disparities in Leading Authorships of Gastroenterology and Hepatology Randomized Controlled Trials
To investigate gender, racial, ethnic, and regional disparities in first and senior authorship positions in gastroenterolo...
Clinical Outcomes and Prognosis of Esophageal Squamous Cell Carcinoma Presenting with Obstruction
Clinical Outcomes and Prognosis of Esophageal Squamous Cell Carcinoma Presenting with Obstruction
The prognosis of esophageal squamous cell carcinoma (ESCC) with obstruction is unclear. This study aimed to analyze clinic...
A Systematic Review and Meta-Analysis of the Efficacy and Safety of Regorafenib in the Treatment of Metastatic Colorectal Cancer
A Systematic Review and Meta-Analysis of the Efficacy and Safety of Regorafenib in the Treatment of Metastatic Colorectal Cancer
Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide. Despite advances in treatment, metastati...
Exploring the Relationship Between KRAS, NRAS, and BRAF Mutations and Clinical Characteristics in Iranian Colorectal Cancer Patients
Exploring the Relationship Between KRAS, NRAS, and BRAF Mutations and Clinical Characteristics in Iranian Colorectal Cancer Patients
Patients with colorectal cancer can benefit from anti-EGFR (epidermal growth factor receptor) therapy. However, this thera...
Expression Pattern of Estrogen Receptor Alpha and Progesterone Receptor in Gallbladder Carcinoma and Their Association with Clinicopathological Parameters and Overall Survival
Expression Pattern of Estrogen Receptor Alpha and Progesterone Receptor in Gallbladder Carcinoma and Their Association with Clinicopathological Parameters and Overall Survival
Gallbladder cancer (GBC) is a highly aggressive malignant tumor with a poor prognosis. Despite being first described two c...
Percutaneous Metallic Stents in Malignant Biliary Obstruction: Comparison of Nitinol and Wall Stents
Percutaneous Metallic Stents in Malignant Biliary Obstruction: Comparison of Nitinol and Wall Stents
Palliation of malign biliary obstruction is important which is commonly carried out by percutaneous biliary stenting. Our ...
Peritoneal Tumour DNA in Peritoneal Fluid: Emerging Tool for Peritoneal Metastasis Detection
Peritoneal Tumour DNA in Peritoneal Fluid: Emerging Tool for Peritoneal Metastasis Detection
The prognostic significance of positive peritoneal cytology still varied between cancer types and geographical origin. How...
Understanding Patient Perspectives to Improve Colorectal Cancer Screening Following the COVID-19 Pandemic: Assessment of a Mailed Fecal Immunochemical Testing Program
Understanding Patient Perspectives to Improve Colorectal Cancer Screening Following the COVID-19 Pandemic: Assessment of a Mailed Fecal Immunochemical Testing Program
Ethical approval This is an observational study. The Provid...
Lack of Adherence to Guidelines on Follow-Up Colonoscopy after an Abnormal Stool Occult Blood Test
Lack of Adherence to Guidelines on Follow-Up Colonoscopy after an Abnormal Stool Occult Blood Test
Competing Interests The authors declare no competing intere...
Role of the Clinical Features and MRI Parameters on Ki-67 Expression in Hepatocellular Carcinoma Patients: Development of a Predictive Nomogram
Role of the Clinical Features and MRI Parameters on Ki-67 Expression in Hepatocellular Carcinoma Patients: Development of a Predictive Nomogram
To develop a nomogram using clinical features and the MRI parameters for preoperatively predicting the expression of Ki-67...
Survival Outcomes in Stage IV Gastric Cancer Patients with Krukenberg Tumors: A Systematic Review and Meta Analysis
Survival Outcomes in Stage IV Gastric Cancer Patients with Krukenberg Tumors: A Systematic Review and Meta Analysis
Stage IV gastric cancer patients with Krukenberg tumors typically exhibit poor survival outcomes, often less than 2&nb...
Can Pretreatment MRI and Planning CT Radiomics Improve Prediction of Complete Pathological Response in Locally Advanced Rectal Cancer Following Neoadjuvant Treatment?
Can Pretreatment MRI and Planning CT Radiomics Improve Prediction of Complete Pathological Response in Locally Advanced Rectal Cancer Following Neoadjuvant Treatment?
The treatment response to neoadjuvant chemoradiation (nCRT) differs largely in individuals treated for rectal cancer. In t...
Risk Factors of Chemotherapy-Induced Thrombocytopenia After Oxaliplatin-Containing Chemotherapy for Gastrointestinal Malignancies
Risk Factors of Chemotherapy-Induced Thrombocytopenia After Oxaliplatin-Containing Chemotherapy for Gastrointestinal Malignancies
Thrombocytopenia is among the most common chemotherapy-related hematologic toxicities. We aim to determine the predictors ...
Single-Center Randomized Trial Comparing Feeding Jejunostomy with Nasojejunal Tube Placement in Patients Undergoing Transhiatal Esophagectomy Post-Neoadjuvant Therapy for Esophageal Cancer
Single-Center Randomized Trial Comparing Feeding Jejunostomy with Nasojejunal Tube Placement in Patients Undergoing Transhiatal Esophagectomy Post-Neoadjuvant Therapy for Esophageal Cancer
Enteral nutrition is the preferred mode of nutrition following esophagectomy. However, the preferred mode of enteral nutri...
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