Camargo MC, Figueiredo C, Machado JC (2019) Review: gastric malignancies: basic aspects. Helicobacter 24:e12642
Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A et al (2018) Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 68:394–424
Karimi P, Islami F, Anandasabapathy S, Freedman ND, Kamangar F (2014) Gastric cancer: descriptive epidemiology, risk factors, screening, and prevention. Cancer Epidemiol Biomark Prev 23:700–713
Sitarz R, Skierucha M, Mielko J, Offerhaus GJA, MAciejewski R, Polkowski WP (2018) Gastric cancer: epidemiology, prevention, classification, and treatment. Cancer Manag Res 10:239
Wittekind C (2015) The development of the TNM classification of gastric cancer. Pathol
Li Y, Wang D, Zhao B, Wang W, Yuan S, Huang C et al (2012) Poor prognosis of gastric adenocarcinoma with decreased expression of AHRR. PLoS One 7:e43555
Apicella M, Corso S, Giordano S (2017) Targeted therapies for gastric cancer: failures and hopes from clinical trials. Oncotarget 8:57654–57669
Salati M, Orsi G, Smyth E, Beretta G, De Vita F, Di Bartolomeo M et al (2019) Gastric cancer: translating novels concepts into clinical practice. Cancer Treat Rev 79:101889
Boyiadzis MM, Kirkwood JM, Marshall JL, Pritchard CC, Azad NS, Gulley JL (2018) Significance and implications of FDA approval of pembrolizumab for biomarker-defined disease. J Immunother Cancer 6:35
Yelamanchi SD, Solanki HS, Radhakrishnan A, Balakrishnan L, Advani J, Raja R et al (2016) Signaling network map of the aryl hydrocarbon receptor. J Cell Commun Signal 10:341
Murray IA, Patterson AD, Perdew GH (2014) Aryl hydrocarbon receptor ligands in cancer: friend and foe. Nat Rev Cancer 14:801–814 h
Safe S, Lee S-O, Jin U-H (2013) Role of the aryl hydrocarbon receptor in carcinogenesis and potential as a drug target. Toxicol Sci 135:1–16
Poland A, Glover E (1973) Studies on the mechanism of toxicity of the chlorinated dibenzo-p-dioxins. Environ Health Perspect 5:245–251
Coumoul X, Fernandez-Salguero PM (2007) The aryl hydrocarbon receptor, more than a xenobiotic-interacting protein. FEBS Lett 581:3608–3615
Feng S, Cao Z, Wang X (2013) Role of aryl hydrocarbon receptor in cancer. Biochim Biophys Acta - Rev Cancer 1836:197–210
Kolluri SK, Jin U-H, Safe S (2017) Role of the aryl hydrocarbon receptor in carcinogenesis and potential as an anti-cancer drug target. Arch Toxicol 91:2497–2513
Peng T-L, Chen J, Mao W, Liu X, Tao Y, Chen L-Z et al (2009) Potential therapeutic significance of increased expression of aryl hydrocarbon receptor in human gastric cancer. World J Gastroenterol 15:1719
Zhu R, Gao C, Wang L, Zhang G, Zhang W, Zhang Z et al (2018) Involvement of aryl hydrocarbon receptor and aryl hydrocarbon receptor repressor in Helicobacter Pylori -related gastric pathogenesis. J Cancer 9:2757–2764
Andersson P, McGuire J, Rubio C, Gradin K, Whitelaw ML, Pettersson S et al (2002) A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors. Proc Natl Acad Sci 99:9990–9995. https://doi.org/10.1073/pnas.152706299
Article CAS PubMed Google Scholar
Peng T-L, Chen J, Mao W, Song X, Chen M-H (2009) Aryl hydrocarbon receptor pathway activation enhances gastric cancer cell invasiveness likely through a c-Jun-dependent induction of matrix metalloproteinase-9. BMC Cell Biol 10:27
Gasiewicz TA, Henry EC, Collins LL (2008) Expression and activity of aryl hydrocarbon receptors in development and Cancer. Crit Rev Eukaryot Gene Expr 18:279–321
Richter CA, Tillitt DE, Hannink M (2001) Regulation of subcellular localization of the aryl hydrocarbon receptor (AhR). Arch Biochem Biophys 389:207–217
Novikov O, Wang Z, Stanford EA, Parks AJ, Ramirez-Cardenas A, Landesman E et al (2016) An aryl hydrocarbon receptor-mediated amplification loop that enforces cell migration in ER − /PR − /Her2 − human breast cancer cells. Mol Pharmacol 90:674–688
Ma J-X, Zhang K-L, Liu X, Ma Y-L, Pei L-N, Zhu Y-F et al (2006) Concurrent expression of aryl hydrocarbon receptor and CYP1A1 but not CYP1A1 MspI polymorphism is correlated with gastric cancers raised in Dalian, China. Cancer Lett 240:253–260
Yin X-F, Chen J, Mao W, Wang Y-H, Chen M-H (2013) Downregulation of aryl hydrocarbon receptor expression decreases gastric cancer cell growth and invasion. Oncol Rep 30:364–370
Wei Y, Zhao L, He W et al (2016) Benzo[a]pyrene promotes gastric cancer cell proliferation and metastasis likely through the aryl hydrocarbon receptor and ERK-dependent induction of MMP9 and c-myc. Int J Oncol 49:2055–2063
Yin X-F, Chen J, Mao W, Wang Y-H, Chen M-H (2012) A selective aryl hydrocarbon receptor modulator 3,3′-Diindolylmethane inhibits gastric cancer cell growth. J Exp Clin Cancer Res 31:46
Lai D-W, Liu S-H, Karlsson AI, Lee W-J, Wang K-B, Chen Y-C et al (2014) The novel aryl hydrocarbon receptor inhibitor biseugenol inhibits gastric tumor growth and peritoneal dissemination. Oncotarget 5. https://doi.org/10.18632/oncotarget.2307
Tsay JJ, Tchou-Wong K-M, Greenberg AK, Pass H, Rom WN (2013) Aryl hydrocarbon receptor and lung Cancer. Anticancer Res 33:1247–1256
PubMed PubMed Central Google Scholar
Jaffrain-Rea M-L, Angelini M, Gargano D, Tichomirowa MA, Daly AF, Vanbellinghen J-F et al (2009) Expression of aryl hydrocarbon receptor (AHR) and AHR-interacting protein in pituitary adenomas: pathological and clinical implications. Endocr Relat Cancer 16:1029–1043. https://doi.org/10.1677/ERC-09-0094
Article CAS PubMed Google Scholar
Uhlen M, Fagerberg L, Hallstrom BM, Lindskog C, Oksvold P, Mardinoglu A et al (2015) Tissue-based map of the human proteome. Science 347:1260419–1260419
Narasimhan S, Stanford Zulick E, Novikov O, Parks A, Schlezinger J, Wang Z et al (2018) Towards resolving the pro- and anti-tumor effects of the aryl hydrocarbon receptor. Int J Mol Sci 19:1388
Ye M, Zhang Y, Gao H, Xu Y, Jing P, Wu J et al (2018) Activation of the aryl hydrocarbon receptor leads to resistance to EGFR TKIs in non–small cell lung Cancer by activating Src-mediated bypass signaling. Clin Cancer Res 24:1227–1239
Comments (0)