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Author correction to “FGF4 protects the liver from immune-mediated injury by activating CaMKKβ-PINK1 signal pathway to inhibit hepatocellular apoptosis” [Acta Pharm Sin B 14 (2024) 1605–1623]
Available online 9 April 2024Author links open overlay panel, , , , , , , , , , , , , , , © 2024 The Author(s). Published ...
Acta Pharmaceutica Sinica B
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Exosomes derived from tumor adjacent fibroblasts efficiently target pancreatic cancer
Pancreatic cancerTumor adjacent normal tissue fibroblasts (NAF)DesmoplasiaExtracellular vesiclesExosomesTumor targetingOrm...
Acta Pharmaceutica Sinica B
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The chromosome-scale assembly of the Notopterygium incisum genome provides insight into the structural diversity of coumarins
Available online 10 April 2024Author links open overlay panel, , , , , , , , , , , , , , , AbstractCoumarins, derived from...
Acta Pharmaceutica Sinica B
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Encoding and display technologies for combinatorial libraries in drug discovery: The coming of age from biology to therapy
Drug discovery is a sophisticated process that incorporates scientific innovations and cutting-edge technologies. Compared...
Acta Pharmaceutica Sinica B
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Julolidinyl aza-BODIPYs as NIR-II fluorophores for the bioimaging of nanocarriers
3,5-JulolidinylAza-BODIPYNanocarriersNear-infrared IIFluorescence imagingAggregation-caused quenchingPolymeric micellesPol...
Acta Pharmaceutica Sinica B
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Characteristic roadmap of linker governs the rational design of PROTACs
Proteolysis targeting chimera (PROTAC) technology represents a groundbreaking development in drug discovery, leveraging th...
Acta Pharmaceutica Sinica B
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Endoplasmic reticulum-targeted delivery of celastrol and PD-L1 siRNA for reinforcing immunogenic cell death and potentiating cancer immunotherapy
ChemoimmunotherapyTargeted drug deliveryEndoplasmic reticulumEndoplasmic reticulum stressImmunogenic cell deathsiRNAExosom...
Acta Pharmaceutica Sinica B
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Discovery and characterization of novel potent non-covalent small molecule inhibitors targeting papain-like protease from SARS-CoV-2
Non-covalent PLpro inhibitorsAntiviral activityStructural-based drug designImidazo[4,5-b]pyridine scaffold© 2024 Published...
Acta Pharmaceutica Sinica B
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Monoclonal antibodies and aptamers: The future therapeutics for Alzheimer’s disease
Available online 17 April 2024Author links open overlay panelAbstractAlzheimer’s disease (AD) is considered the most commo...
Acta Pharmaceutica Sinica B
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Author correction to ‘Identification of the dietary supplement capsaicin as an inhibitor of Lassa virus entry’ [Acta Pharmaceutica Sinica B 10 (2020) 789–798]
Available online 18 April 2024Author links open overlay panelKe Tang a b †, Xiaoyu Zhang a b †, Ying Guo a bShow moreRecom...
Acta Pharmaceutica Sinica B
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Ailanthone ameliorates pulmonary fibrosis by suppressing JUN-dependent MEOX1 activation
AilanthoneMEOX1Pulmonary fibrosisJUNTGF-β1High-throughput screeningNatural product© 2024 The Author(s). Published by Elsev...
Acta Pharmaceutica Sinica B
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Antitumor activity and low gastrointestinal toxicity of a novel selective inhibitor of nuclear export, SZJK-0421, in multiple myeloma
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2024 Elsevier B.V., its licensors, an...
Acta Pharmaceutica Sinica B
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Lipid-nanoparticle-enabled nucleic acid therapeutics for liver disorders
Available online 22 April 2024Author links open overlay panel, , , , , , AbstractInherited genetic disorders of the liver ...
Acta Pharmaceutica Sinica B
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Mechanical regulation of lipid and sugar absorption by Piezo1 in enterocytes
Piezo1DGAT2SGLT1Lipid metabolismObesityMechanical sensingIntestinal lipid absorptionIntestinal glucose absorption© 2024 Th...
Acta Pharmaceutica Sinica B
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Commentary: The central lymphatic drainage in pharmacological, surgical and physical therapies of Alzheimer's disease
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2024 Elsevier B.V., its licensors, an...
Acta Pharmaceutica Sinica B
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Phenylalanine deprivation inhibits multiple myeloma progression by perturbing endoplasmic reticulum homeostasis
multiple myelomaPhenylalanineAmino acid metabolismNutrient deprivationCancer therapyEndoplasmic reticulum stressATF3Apopto...
Acta Pharmaceutica Sinica B
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Enhancing immunotherapy efficacy against MHC-I deficient triple-negative breast cancer using LCL161-loaded macrophage membrane-decorated nanoparticles
MHC-I deficiencyMacrophageCD47ImmunotherapyTriple-negative breast cancerPhagocytosisImmune checkpointInnate immunity© 2024...
Acta Pharmaceutica Sinica B
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PIM1–HDAC2 axis modulates intestinal homeostasis through epigenetic modification
Available online 24 April 2024Author links open overlay panel, , , , , , , , , , , , , , AbstractThe mucosal barrier is cr...
Acta Pharmaceutica Sinica B
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Inhibition of xanthine oxidase alleviated pancreatic necrosis via HIF-1α-regulated LDHA and NLRP3 signaling pathway in acute pancreatitis
Xanthine oxidase inhibitormulti-omicsHIF-1αnecrotizing acute pancreatitislactatetherapeutic targetNLRP3metabolic flux© 202...
Acta Pharmaceutica Sinica B
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Therapeutic strategies of targeting non-apoptotic regulated cell death (RCD) with small-molecule compounds in cancer
Regulated cell death (RCD) is a controlled form of cell death orchestrated by one or more cascading signaling pathways, ma...
Acta Pharmaceutica Sinica B
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Commentary: Mammokine directs beige adipocytes to reserve energy for milk production in breast
Available online 4 December 2023Author links open overlay panel, KeywordsbeigeBreastEpitheliail cellsscRNA-seqThermogenesi...
Acta Pharmaceutica Sinica B
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Purpurolide C-based microneedle promotes macrophage-mediated diabetic wound healing via inhibiting TLR4-MD2 dimerization and MYD88 phosphorylation
DiabetesWound healingPurpurolide CLiposome and GelMA-based microneedle patchesMacrophage polarizationInflammationDrug deli...
Acta Pharmaceutica Sinica B
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Design and discovery of a highly potent ultralong-acting GLP-1 and glucagon co-agonist for attenuating renal fibrosis
Available online 18 November 2023Author links open overlay panel, , , , , , , , , , , , , , , , AbstractThe role of co-ago...
Acta Pharmaceutica Sinica B
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In situ autophagy regulation in synergy with phototherapy for breast cancer treatment
AutophagyTumor phototherapySynergistic sensitizationHCQTRANSFERRINDisulfide bond reconstructionGSHBiomimetic mineralized n...
Acta Pharmaceutica Sinica B
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Late-stage modification of bioactive compounds: Improving druggability through efficient molecular editing
Available online 18 November 2023Author links open overlay panel, , , , , , AbstractSynthetic chemistry plays an indispens...
Acta Pharmaceutica Sinica B
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The emerging tumor microbe microenvironment: From delineation to multidisciplinary approach-based interventions
Intratumoral microbiota has become research hotspots, and emerges as a non-negligent new component of tumor microenvironme...
Acta Pharmaceutica Sinica B
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Phase separation of Nur77 mediates XS561-induced apoptosis by promoting the formation of Nur77/Bcl-2 condensates
Available online 17 November 2023Author links open overlay panel, , , , , , , , , , , AbstractThe orphan nuclear receptor ...
Acta Pharmaceutica Sinica B
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Ginsenoside modified lipid-coated perfluorocarbon nanodroplets: A novel approach to reduce complement protein adsorption and prolong in vivo circulation
Lipid-coated perfluorocarbon nanodropletsProtein coronaComplement C3PhagocytosisGinsenoside lipid-coated perfluorocarbon n...
Acta Pharmaceutica Sinica B
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Author correction to “Coordinated regulation of BACH1 and mitochondrial metabolism through tumor targeted self-assembled nanoparticles for effective triple negative breast cancer combination therapy” [Acta Pharmaceutica Sinica B 12 (2022) 3934–3951]
Volume 13, Issue 11, November 2023, Pages 4661-4663Author links open overlay panel, , , , , , , , © 2023 Chinese Pharmaceu...
Acta Pharmaceutica Sinica B
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Author correction to “Neutralization of SARS-CoV-2 pseudovirus using ACE2-engineered extracellular vesicles” [Acta Pharmaceutica Sinica B 12 (2022) 1523–1533]
Volume 13, Issue 11, November 2023, Pages 4664-4666Author links open overlay panel, , , , , , , , © 2023 Chinese Pharmaceu...
Acta Pharmaceutica Sinica B
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