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SCI Abstract
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Effectiveness of Nirmatrelvir-Ritonavir for the Prevention of COVID-19–Related Hospitalization and Mortality: A Systematic Literature Review
Background: Nirmatrelvir/ritonavir (NMV/r) is an oral antiviral drug used to treat mild-to-modera
American Journal Of Therapeutics
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Commentary on Effectiveness of Nirmatrelvir–Ritonavir for the Prevention of COVID-19–Related Hospitalization and Mortality: A Systematic Literature Review
In this issue of the American Journal of Therapeutics, Cha-Silva et al publish the article Effectiveness of Nirmatrelvir–R...
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Cognitive Outcomes in Nonacute Patients With Schizophrenia Treated With Long-Acting Injectable Antipsychotics Versus Oral Antipsychotics
Background: Patients with schizophrenia often face challenges related to cognitive function, affe
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Sex Differences in Cardiovascular Management: A Call for Better Acknowledgment—Part 1 Pharmacological Differences in Women and Men; How Relevant Are They?
Background: Sex differences (SDs) in pharmacology of cardiovascular (CV) drugs have been describe
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Edaravone Oral Suspension: A Neuroprotective Agent to Treat Amyotrophic Lateral Sclerosis
Background: Amyotrophic lateral sclerosis (ALS) is characterized by loss of motor neurons due to
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Drug Promotions Between Ethics, Regulations, and Financial Interests
Background: The promotion of the latest medicines produced by the pharmaceutical industry is an i
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Pharmacological Management of Cholera: A Century of Expert Opinions in Cecil Textbook of Medicine
Background: Cholera is a potentially lethal diarrheal disease produced by Vibrio cholerae serotyp
American Journal Of Therapeutics
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Roflumilast 0.3% Cream: a Phosphodiesterase 4 Inhibitor for the Treatment of Chronic Plaque Psoriasis
Background: Plaque psoriasis is a chronic dermatologic autoimmune disease that affects adults and
American Journal Of Therapeutics
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Nivolumab/Relatlimab-rmbw: A Novel Dual Combination Therapy to Treat Adult and Pediatric Patients With Unresectable or Metastatic Melanoma
Background: Immune checkpoint inhibitors control effector mechanisms and work to restore downregu
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Mitapivat: A Quinolone Sulfonamide to Manage Hemolytic Anemia in Adults With Pyruvate Kinase Deficiency
Background: Pyruvate kinase (PK) deficiency is a rare enzyme-linked glycolytic defect resulting i
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The New Mythology of the Body and the Transformation of the Therapeutic Space
Background: The history of medicine has flowed in the wake of knowledge and social perceptions ab
American Journal Of Therapeutics
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Fatal Myocarditis After COVID-19 Vaccination: Fourteen Autopsy-Confirmed Cases: Erratum
The title of Table 1 is being corrected to the following: Demographic and autopsy features of 14 cases of fatal myocarditi...
American Journal Of Therapeutics
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Prevalence of Dabigatran-Associated Esophagitis on Upper Gastrointestinal Endoscopy: A Systematic Review and Meta-analysis
1Division of Gastroenterology and Hepatology, Indiana University, Indianapolis, IN 2Division of Cardiology, U...
American Journal Of Therapeutics
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Bed Rest After Acute Myocardial Infarction: A Century of Expert Opinions in Cecil Textbook of Medicine
Background: Complete bed rest has been a component of the management of acute myocardial infarcti
American Journal Of Therapeutics
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Daridorexant, an Orexin Receptor Antagonist for the Management of Insomnia
Background: Insomnia is a common sleep disorder that is diagnosed primarily by patients' subjecti
American Journal Of Therapeutics
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Evaluating the Efficacy and Pharmacoeconomics of Semaglutide and Tirzepatide in the Setting of Obesity
Background: Obesity is a major and growing public health concern. The associated cost for obesity
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Outcome of COVID-19 mRNA Vaccination in Patients Treated With Clozapine WHO Previously Went Through SARS-COV-2 Infection
Background: The outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pand
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Complement Inhibitors in the Management of Complement-Mediated Hemolytic Uremic Syndrome and Paroxysmal Nocturnal Hemoglobinuria
Background: Complement-mediated HUS (CM-HUS) and paroxysmal nocturnal hemoglobinuria (PNH) are ra
American Journal Of Therapeutics
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Tirzepatide: A Dual Glucose-Dependent Insulinotropic Polypeptide and Glucagon-Like Peptide-1 Agonist for the Management of Type 2 Diabetes Mellitus: Erratum
In the section “SURMOUNT-1,” the third sentence of the second paragraph is being corrected to the following: “T...
American Journal Of Therapeutics
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Advances in Genetic Editing of the Human Embryo
Background: Genetic engineering has allowed a major development of research in this field, with s
American Journal Of Therapeutics
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Abrocitinib for the Treatment of Moderate-to-Severe Atopic Dermatitis
Background: Atopic dermatitis (AD) is ranked as the third most prevalent skin condition with a wo
American Journal Of Therapeutics
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Anakinra—An Interleukin-1 Receptor Antagonist for COVID-19
Background: Coronavirus disease (COVID-19) caused by SARS-CoV-2 virus caused a global pandemic in
American Journal Of Therapeutics
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Oral Chemotherapeutic Ingestions Reported to a Poison Control Center Treated in a Health Care Facility
Background: The approach to cancer chemotherapy has changed in recent years, and there are severa
American Journal Of Therapeutics
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The Challenge of Intermediate-Risk Pulmonary Embolism
Background: Intermediate-risk pulmonary embolism is a common disease that is associated with sign
American Journal Of Therapeutics
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