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Effectiveness of Nirmatrelvir-Ritonavir for the Prevention of COVID-19–Related Hospitalization and Mortality: A Systematic Literature Review
Effectiveness of Nirmatrelvir-Ritonavir for the Prevention of COVID-19–Related Hospitalization and Mortality: A Systematic Literature Review
Background: Nirmatrelvir/ritonavir (NMV/r) is an oral antiviral drug used to treat mild-to-modera
Commentary on Effectiveness of Nirmatrelvir–Ritonavir for the Prevention of COVID-19–Related Hospitalization and Mortality: A Systematic Literature Review
Commentary on Effectiveness of Nirmatrelvir–Ritonavir for the Prevention of COVID-19–Related Hospitalization and Mortality: A Systematic Literature Review
In this issue of the American Journal of Therapeutics, Cha-Silva et al publish the article Effectiveness of Nirmatrelvir–R...
Cognitive Outcomes in Nonacute Patients With Schizophrenia Treated With Long-Acting Injectable Antipsychotics Versus Oral Antipsychotics
Cognitive Outcomes in Nonacute Patients With Schizophrenia Treated With Long-Acting Injectable Antipsychotics Versus Oral Antipsychotics
Background: Patients with schizophrenia often face challenges related to cognitive function, affe
Sex Differences in Cardiovascular Management: A Call for Better Acknowledgment—Part 1 Pharmacological Differences in Women and Men; How Relevant Are They?
Sex Differences in Cardiovascular Management: A Call for Better Acknowledgment—Part 1 Pharmacological Differences in Women and Men; How Relevant Are They?
Background: Sex differences (SDs) in pharmacology of cardiovascular (CV) drugs have been describe
Edaravone Oral Suspension: A Neuroprotective Agent to Treat Amyotrophic Lateral Sclerosis
Edaravone Oral Suspension: A Neuroprotective Agent to Treat Amyotrophic Lateral Sclerosis
Background: Amyotrophic lateral sclerosis (ALS) is characterized by loss of motor neurons due to
Drug Promotions Between Ethics, Regulations, and Financial Interests
Drug Promotions Between Ethics, Regulations, and Financial Interests
Background: The promotion of the latest medicines produced by the pharmaceutical industry is an i
Pharmacological Management of Cholera: A Century of Expert Opinions in Cecil Textbook of Medicine
Pharmacological Management of Cholera: A Century of Expert Opinions in Cecil Textbook of Medicine
Background: Cholera is a potentially lethal diarrheal disease produced by Vibrio cholerae serotyp
Roflumilast 0.3% Cream: a Phosphodiesterase 4 Inhibitor for the Treatment of Chronic Plaque Psoriasis
Roflumilast 0.3% Cream: a Phosphodiesterase 4 Inhibitor for the Treatment of Chronic Plaque Psoriasis
Background: Plaque psoriasis is a chronic dermatologic autoimmune disease that affects adults and
Nivolumab/Relatlimab-rmbw: A Novel Dual Combination Therapy to Treat Adult and Pediatric Patients With Unresectable or Metastatic Melanoma
Nivolumab/Relatlimab-rmbw: A Novel Dual Combination Therapy to Treat Adult and Pediatric Patients With Unresectable or Metastatic Melanoma
Background: Immune checkpoint inhibitors control effector mechanisms and work to restore downregu
Mitapivat: A Quinolone Sulfonamide to Manage Hemolytic Anemia in Adults With Pyruvate Kinase Deficiency
Mitapivat: A Quinolone Sulfonamide to Manage Hemolytic Anemia in Adults With Pyruvate Kinase Deficiency
Background: Pyruvate kinase (PK) deficiency is a rare enzyme-linked glycolytic defect resulting i
The New Mythology of the Body and the Transformation of the Therapeutic Space
The New Mythology of the Body and the Transformation of the Therapeutic Space
Background: The history of medicine has flowed in the wake of knowledge and social perceptions ab
Fatal Myocarditis After COVID-19 Vaccination: Fourteen Autopsy-Confirmed Cases: Erratum
Fatal Myocarditis After COVID-19 Vaccination: Fourteen Autopsy-Confirmed Cases: Erratum
The title of Table 1 is being corrected to the following: Demographic and autopsy features of 14 cases of fatal myocarditi...
Prevalence of Dabigatran-Associated Esophagitis on Upper Gastrointestinal Endoscopy: A Systematic Review and Meta-analysis
Prevalence of Dabigatran-Associated Esophagitis on Upper Gastrointestinal Endoscopy: A Systematic Review and Meta-analysis
1Division of Gastroenterology and Hepatology, Indiana University, Indianapolis, IN 2Division of Cardiology, U...
Bed Rest After Acute Myocardial Infarction: A Century of Expert Opinions in Cecil Textbook of Medicine
Bed Rest After Acute Myocardial Infarction: A Century of Expert Opinions in Cecil Textbook of Medicine
Background: Complete bed rest has been a component of the management of acute myocardial infarcti
Daridorexant, an Orexin Receptor Antagonist for the Management of Insomnia
Daridorexant, an Orexin Receptor Antagonist for the Management of Insomnia
Background: Insomnia is a common sleep disorder that is diagnosed primarily by patients' subjecti
Evaluating the Efficacy and Pharmacoeconomics of Semaglutide and Tirzepatide in the Setting of Obesity
Evaluating the Efficacy and Pharmacoeconomics of Semaglutide and Tirzepatide in the Setting of Obesity
Background: Obesity is a major and growing public health concern. The associated cost for obesity
Outcome of COVID-19 mRNA Vaccination in Patients Treated With Clozapine WHO Previously Went Through SARS-COV-2 Infection
Outcome of COVID-19 mRNA Vaccination in Patients Treated With Clozapine WHO Previously Went Through SARS-COV-2 Infection
Background: The outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pand
Complement Inhibitors in the Management of Complement-Mediated Hemolytic Uremic Syndrome and Paroxysmal Nocturnal Hemoglobinuria
Complement Inhibitors in the Management of Complement-Mediated Hemolytic Uremic Syndrome and Paroxysmal Nocturnal Hemoglobinuria
Background: Complement-mediated HUS (CM-HUS) and paroxysmal nocturnal hemoglobinuria (PNH) are ra
Tirzepatide: A Dual Glucose-Dependent Insulinotropic Polypeptide and Glucagon-Like Peptide-1 Agonist for the Management of Type 2 Diabetes Mellitus: Erratum
Tirzepatide: A Dual Glucose-Dependent Insulinotropic Polypeptide and Glucagon-Like Peptide-1 Agonist for the Management of Type 2 Diabetes Mellitus: Erratum
In the section “SURMOUNT-1,” the third sentence of the second paragraph is being corrected to the following: “T...
Advances in Genetic Editing of the Human Embryo
Advances in Genetic Editing of the Human Embryo
Background: Genetic engineering has allowed a major development of research in this field, with s
Abrocitinib for the Treatment of Moderate-to-Severe Atopic Dermatitis
Abrocitinib for the Treatment of Moderate-to-Severe Atopic Dermatitis
Background: Atopic dermatitis (AD) is ranked as the third most prevalent skin condition with a wo
Anakinra—An Interleukin-1 Receptor Antagonist for COVID-19
Anakinra—An Interleukin-1 Receptor Antagonist for COVID-19
Background: Coronavirus disease (COVID-19) caused by SARS-CoV-2 virus caused a global pandemic in
Oral Chemotherapeutic Ingestions Reported to a Poison Control Center Treated in a Health Care Facility
Oral Chemotherapeutic Ingestions Reported to a Poison Control Center Treated in a Health Care Facility
Background: The approach to cancer chemotherapy has changed in recent years, and there are severa
The Challenge of Intermediate-Risk Pulmonary Embolism
The Challenge of Intermediate-Risk Pulmonary Embolism
Background: Intermediate-risk pulmonary embolism is a common disease that is associated with sign
Tirzepatide: A Dual Glucose-dependent Insulinotropic Polypeptide and Glucagon-Like Peptide-1 Agonist for the Management of Type 2 Diabetes Mellitus
Tirzepatide: A Dual Glucose-dependent Insulinotropic Polypeptide and Glucagon-Like Peptide-1 Agonist for the Management of Type 2 Diabetes Mellitus
Background: Diabetes is a chronic disease that can lead to many complications, and controlling gl
Residual Disease Threshold After Primary Surgical Treatment for Advanced Epithelial Ovarian Cancer, Part 1: A Systematic Review and Network Meta-Analysis
Residual Disease Threshold After Primary Surgical Treatment for Advanced Epithelial Ovarian Cancer, Part 1: A Systematic Review and Network Meta-Analysis
Background: We present a systematic review and network meta-analysis (NMA) that is the precursor
Sugammadex-Induced Bradycardia and Anaphylaxis and Proposed Mechanism for Adverse Events
Sugammadex-Induced Bradycardia and Anaphylaxis and Proposed Mechanism for Adverse Events
Wolters Kluwer Health ...
Propofol-Associated Priapism: Erratum
Propofol-Associated Priapism: Erratum
Propofol-Associated Priapism: Erratum : American Journal of Therapeutics ...
QTc Intervals in Drug Poisoning Patients With Tricyclic Antidepressants and Selective Serotonin Reuptake Inhibitors: Erratum
QTc Intervals in Drug Poisoning Patients With Tricyclic Antidepressants and Selective Serotonin Reuptake Inhibitors: Erratum
QTc Intervals in Drug Poisoning Patients With Tricyclic Anti... : American Journal of Therapeutics ...
Same-Day Deaths After COVID-19 Vaccinations: Autopsy Findings in 54 Cases
Same-Day Deaths After COVID-19 Vaccinations: Autopsy Findings in 54 Cases
The largest immunization effort in world history is underway, and 12.7 billon doses of COVID-19 vaccines have been adminis...
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