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Choristoma: a very rare cause of thyroid nodule. Case report and literature review
Choristoma: a very rare cause of thyroid nodule. Case report and literature review
Choristoma is a well-defined benign lesion formed by histologically normal tissue in an unusual location. Diagnosis is con...
The molecular genetics of adrenal cushing
The molecular genetics of adrenal cushing
Adrenal Cushing represents 20% of cases of endogenous hypercorticism. Unilateral cortisol-producing adenoma (CPA), a benig...
Challenges and pitfalls in the management of endocrine toxicities from immune checkpoint inhibitors: a case presentation of synchronous thyrotoxicosis and primary adrenal insufficiency in a melanoma patient
Challenges and pitfalls in the management of endocrine toxicities from immune checkpoint inhibitors: a case presentation of synchronous thyrotoxicosis and primary adrenal insufficiency in a melanoma patient
Immune checkpoint inhibitors have revolutionized the therapeutic approach to several solid tumors, becoming the standard o...
A short review of current knowledge regarding long-term treatment of Graves’ disease with antithyroid drugs
A short review of current knowledge regarding long-term treatment of Graves’ disease with antithyroid drugs
Graves’ disease is the most common form of hyperthyroidism, especially in younger people. Current European guideline...
Metachronous metastasis of papillary thyroid carcinoma to the parotid gland: a case report and review of the literature
Metachronous metastasis of papillary thyroid carcinoma to the parotid gland: a case report and review of the literature
We present a case of metachronous metastasis of papillary thyroid carcinoma to the parotid gland, this being an extremely ...
Lateralization outcomes of bilateral inferior petrosal sinus sampling: desmopressin vs CRH
Lateralization outcomes of bilateral inferior petrosal sinus sampling: desmopressin vs CRH
Bilateral inferior petrosal sinus sampling (BIPSS) is the gold standard for localizing ACTH-dependent Cushing’s synd...
Limited preventive effects of empagliflozin against metabolic dysfunction-associated steatotic liver disease in a mouse model of fast food diet
Limited preventive effects of empagliflozin against metabolic dysfunction-associated steatotic liver disease in a mouse model of fast food diet
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a highly prevalent disease with limited treatment opti...
The Somogyi hypothesis: a parallelism with Michael Somogyi’s life
The Somogyi hypothesis: a parallelism with Michael Somogyi’s life
Michael Somogyi (Somogyi Mihály, 1883–1971) was a Hungarian biochemist who developed his scientific career in E...
Highlighting the contribution of the Greek physician Theodoros Aretaios to the history of thyroidectomy
Highlighting the contribution of the Greek physician Theodoros Aretaios to the history of thyroidectomy
Theodoros Aretaios (1829–1893), having pursued advanced studies at home and abroad and possessing a wide range of co...
Female-specific risk factors for cardiovascular disease: an update
Female-specific risk factors for cardiovascular disease: an update
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. While it was previously believed t...
Serum phosphate levels at diagnosis predict long-term risk for hypopituitarism in patients with acromegaly
Serum phosphate levels at diagnosis predict long-term risk for hypopituitarism in patients with acromegaly
Excess growth hormone (GH) secretion in acromegaly has a major impact on mineral balance and serum phosphate levels. Howev...
Endocrine-disrupting effects of bisphenol-A, thiamethoxam, and fipronil in hormone-naïve transmen compared to cis-women
Endocrine-disrupting effects of bisphenol-A, thiamethoxam, and fipronil in hormone-naïve transmen compared to cis-women
Current evidence suggests that the etiology of gender dysphoria (GD) is multifactorial: this, however, remains unclear. En...
Thyroid complications after hemopoietic stem cell transplantation in children and adolescents
Thyroid complications after hemopoietic stem cell transplantation in children and adolescents
To evaluate the prevalence of thyroid dysfunction and its association with possible contributing factors related to diagno...
Performance of ACR-TIRADS in assessing thyroid nodules does not vary according to patient age
Performance of ACR-TIRADS in assessing thyroid nodules does not vary according to patient age
A few studies have evaluated the performance of the American College of Radiology Thyroid Imaging Reporting And Data Syste...
A toddler with severe vitamin D-dependent rickets type 1 A (VDDR1A), hungry bone syndrome, and severe RSV infection: presentation and therapeutic challenges
A toddler with severe vitamin D-dependent rickets type 1 A (VDDR1A), hungry bone syndrome, and severe RSV infection: presentation and therapeutic challenges
Vitamin D-dependent rickets type 1 A (VDDR1A) is an autosomal recessive disorder due to mutations in the CYP27B1 ...
46,ΧΥ DSD in an adolescent with a novel de novo variant of the NR5A1 gene - case report and literature review
46,ΧΥ DSD in an adolescent with a novel de novo variant of the NR5A1 gene - case report and literature review
In addition to chromosomal abnormalities, several genes have been implicated as causes of disorders of sex development (DS...
Examining aldosterone plasma concentration alterations post-ACTH stimulation in healthy subjects: a systematic literature review and meta-analysis on ACTH’s role in aldosterone secretion
Examining aldosterone plasma concentration alterations post-ACTH stimulation in healthy subjects: a systematic literature review and meta-analysis on ACTH’s role in aldosterone secretion
Adrenocorticotropic hormone (ACTH), in addition to the renin–angiotensin–aldosterone axis, is a potent aldoste...
Testosterone therapy for functional hypogonadism in middle-aged and elderly males: current evidence and future perspectives
Testosterone therapy for functional hypogonadism in middle-aged and elderly males: current evidence and future perspectives
Population aging is a global phenomenon driving research focus toward preventing and managing age-related disorders. Funct...
Fibroblast growth-factor 23-Klotho axis is associated with systemic inflammation and myokine profile in children with chronic kidney disease
Fibroblast growth-factor 23-Klotho axis is associated with systemic inflammation and myokine profile in children with chronic kidney disease
Chronic kidney disease is linked to a disturbed fibroblast growth factor-23 (FGF23)-Klotho axis and an imbalance between m...
TSH is independently associated with remnant cholesterol in euthyroid adults: a cross-sectional study based on 29,708 individuals
TSH is independently associated with remnant cholesterol in euthyroid adults: a cross-sectional study based on 29,708 individuals
The study aims to investigate the relationship between thyroid-stimulating hormone (TSH) and remnant cholesterol (RC) in e...
Expanding the phenotypic spectrum of LHCGR signal peptide insertion variant: novel clinical and allelic findings causing Leydig cell hypoplasia type II
Expanding the phenotypic spectrum of LHCGR signal peptide insertion variant: novel clinical and allelic findings causing Leydig cell hypoplasia type II
Leydig cell hypoplasia (LCH) type II is a rare disease with only a few cases reported. Patients presented with hypospadias...
Clinical prediction model for primary aldosteronism subtyping and special focus on adrenal volumetric assessment
Clinical prediction model for primary aldosteronism subtyping and special focus on adrenal volumetric assessment
Our aim was to develop a prediction model based on a simple score with clinical, laboratory, and imaging findings for the ...
The causal impact of gut microbiota on circulating adipokine concentrations: a two-sample Mendelian randomization study
The causal impact of gut microbiota on circulating adipokine concentrations: a two-sample Mendelian randomization study
Evidence from previous experimental and observational research demonstrates that the gut microbiota is related to circulat...
Reference intervals for thyroid function from the fifth to seventh day of life in twin-pregnancy preterm neonates: an 8-year retrospective study
Reference intervals for thyroid function from the fifth to seventh day of life in twin-pregnancy preterm neonates: an 8-year retrospective study
The immature and developing hypothalamic-pituitary-thyroid axis leads to different levels of thyroid function in twin neon...
Association between serum TSH concentration and bone mineral density: an umbrella review
Association between serum TSH concentration and bone mineral density: an umbrella review
The aim of this study was to summarize the results of previous studies, standardize the data, and present new statistical ...
Evaluation of the possible impact of the fear of hypoglycemia on diabetes management in children and adolescents with type 1 diabetes mellitus and their parents: a cross-sectional study
Evaluation of the possible impact of the fear of hypoglycemia on diabetes management in children and adolescents with type 1 diabetes mellitus and their parents: a cross-sectional study
Hypoglycemia represents a significant source of anxiety for children with type 1 diabetes mellitus (T1DM) and their careta...
When rare diseases crisscross within the same patient: von Hippel-Lindau and type 1 gastric neuroendocrine tumor
When rare diseases crisscross within the same patient: von Hippel-Lindau and type 1 gastric neuroendocrine tumor
Von-Hippel-Lindau (VHL) is a genetic multisystem disorder characterized by visceral cysts and benign and malignant tumors ...
EndoBridge 2023: highlights and pearls
EndoBridge 2023: highlights and pearls
EndoBridge 2023 took place on October 20–22, 2023, in Antalya, Turkey. Accredited by the European Council, the 3-day...
Synergistic neuroprotective action of prolactin and 17β-estradiol on kainic acid-induced hippocampal injury and long-term memory deficit in ovariectomized rats
Synergistic neuroprotective action of prolactin and 17β-estradiol on kainic acid-induced hippocampal injury and long-term memory deficit in ovariectomized rats
The neuroprotective actions of the ovarian hormone 17β-estradiol (E2) against different brain lesions have been const...
Thyroid dysfunction due to trace element deficiency—not only selenium but also zinc
Thyroid dysfunction due to trace element deficiency—not only selenium but also zinc
Levels of serum selenium (Se) and zinc (Zn) decrease when total parental nutrition (TPN) is administered without trace ele...
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