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How safe are proprotein convertase subtilisinekexin type 9 inhibitors in diabetes?
How safe are proprotein convertase subtilisinekexin type 9 inhibitors in diabetes?
Purpose of review To examine the safety of proprotein convertase subtilisinekexin type 9 (PCSK9)
Proprotein convertase subtilisin/kexin type 9-inhibition across different patient populations
Proprotein convertase subtilisin/kexin type 9-inhibition across different patient populations
Purpose of review Monoclonal antibodies (mAb) targeting proprotein convertase subtilisin/kexin ty
APOE and familial hypercholesterolemia
APOE and familial hypercholesterolemia
Purpose of review Autosomal dominant hypercholesterolemia is a common cause of cardiovascular dis
Familial hypercholesterolemia-Plus: is the metabolic syndrome changing the clinical picture of familial hypercholesterolemia?
Familial hypercholesterolemia-Plus: is the metabolic syndrome changing the clinical picture of familial hypercholesterolemia?
Purpose of review The purpose of this review article was to describe recent advances in our knowl
Pancreatic and cardiometabolic complications of severe hypertriglyceridaemia
Pancreatic and cardiometabolic complications of severe hypertriglyceridaemia
Purpose of review This review endeavours to explore the aetiopathogenesis and impact of severe hy
Paraoxonase 1: evolution of the enzyme and of its role in protecting against atherosclerosis
Paraoxonase 1: evolution of the enzyme and of its role in protecting against atherosclerosis
Purpose of review To review the discoveries which led to the concept that serum paraoxonase 1 (PO
Angiopoietin-like protein 8: a multifaceted protein instrumental in regulating triglyceride metabolism
Angiopoietin-like protein 8: a multifaceted protein instrumental in regulating triglyceride metabolism
Purpose of review The angiopoietin-like (ANGPTL) proteins ANGPTL3 and ANGPTL4 are critical lipopr
The current state of apolipoprotein E in dyslipidemia
The current state of apolipoprotein E in dyslipidemia
Purpose of review Apolipoprotein E (apoE) plays a pivotal role in lipid metabolism in the periphe
Genetic variation in apolipoprotein A-V in hypertriglyceridemia
Genetic variation in apolipoprotein A-V in hypertriglyceridemia
Purpose of review While biallelic rare APOA5 pathogenic loss-of-function (LOF) variants cause fam
Novel functions of Tribbles-homolog 1 in liver, adipocytes and atherosclerosis
Novel functions of Tribbles-homolog 1 in liver, adipocytes and atherosclerosis
Purpose of review Human genetics studies have sparked great interest in the pseudokinase Tribbles
Genetic testing for familial hypercholesterolemia
Genetic testing for familial hypercholesterolemia
Purpose of review Despite familial hypercholesterolemia (FH) being the most common genetic cause
Intracellular lipase and regulation of the lipid droplet
Intracellular lipase and regulation of the lipid droplet
Purpose of review Lipid droplets are increasingly recognized as distinct intracellular organelles
Genotype–phenotype correlation in a large cohort of pediatric patients with heterozygous and homozygous familial hypercholesterolemia
Genotype–phenotype correlation in a large cohort of pediatric patients with heterozygous and homozygous familial hypercholesterolemia
Background Familial hypercholesterolemia (FH) is a genetic disorder characterized by elevated low
Strategies of improving adherence to lipid-lowering therapy in patients with atherosclerotic cardiovascular disease
Strategies of improving adherence to lipid-lowering therapy in patients with atherosclerotic cardiovascular disease
Purpose of review Lowering LDL-C has been shown to reduce ASCVD events, yet many ASCVD patients d
Ups and downs in PCSK9 inhibition in the cardiovascular arena: a review
Ups and downs in PCSK9 inhibition in the cardiovascular arena: a review
Purpose of review This article reviews PCSK9 inhibitors (PCSK9i) with a focus on clinically relev
The pathophysiology of excess plasma-free cholesterol
The pathophysiology of excess plasma-free cholesterol
Purpose of review Several large studies have shown increased mortality due to all-causes and to a
Predictors of cardiovascular risk in familial hypercholesterolemia
Predictors of cardiovascular risk in familial hypercholesterolemia
Purpose of review Familial hypercholesterolemia is associated with an increased risk of cardiovas
Triglyceride-rich lipoprotein cholesterol and cardiovascular risk
Triglyceride-rich lipoprotein cholesterol and cardiovascular risk
Purpose of review The triglyceride-rich apoB lipoprotein particles make up a minority of the apoB
Sweet swell of burning fat: emerging role of high-density lipoprotein in energy homeostasis
Sweet swell of burning fat: emerging role of high-density lipoprotein in energy homeostasis
Purpose of review Metabolism of lipids and lipoproteins, including high-density lipoprotein (HDL)
Angiopoietin-like 3 inhibition and the liver: less is more?
Angiopoietin-like 3 inhibition and the liver: less is more?
Purpose of review The aim of this study was to discuss the potential mechanisms and implications
The multiple roles of lysophosphatidic acid in vascular disease and atherosclerosis
The multiple roles of lysophosphatidic acid in vascular disease and atherosclerosis
Purpose of review To explore the multiple roles that lysophosphatidic acid (LPA) plays in vascula
Aspirin and lipoprotein(a) in primary prevention
Aspirin and lipoprotein(a) in primary prevention
Purpose of review Lipoprotein(a) [Lp(a)] is causally associated with cardiovascular diseases, and
A new SPRING in lipid metabolism
A new SPRING in lipid metabolism
Purpose of review The SREBP transcription factors are master regulators of lipid homeostasis owin
Phospholipid transport by ABCA1: the extracellular translocase or alternating access model?
Phospholipid transport by ABCA1: the extracellular translocase or alternating access model?
Purpose of review ATP-binding cassette transporter A1 (ABCA1) plays a key role in high-density li
Macrophage inflammarafts in atherosclerosis
Macrophage inflammarafts in atherosclerosis
Purpose of review Advances in single cell techniques revealed a remarkable diversity in macrophag
Established and potential cardiovascular risk factors in metabolic syndrome: Effect of bariatric surgery
Established and potential cardiovascular risk factors in metabolic syndrome: Effect of bariatric surgery
Purpose of review The aim of this review was to provide an overview of the role of novel biomarke
Considerations for routinely testing for high lipoprotein(a)
Considerations for routinely testing for high lipoprotein(a)
Purpose of review Lipoprotein (a) [Lp(a)] is a likely causal risk factor for atherosclerotic card
Inclisiran: present and future perspectives of a new effective LDL cholesterol-lowering agent
Inclisiran: present and future perspectives of a new effective LDL cholesterol-lowering agent
Purpose of review To highlight critical aspects of inclisiran, from preclinical studies to curren
Bempedoic acid for nonalcoholic fatty liver disease: evidence and mechanisms of action
Bempedoic acid for nonalcoholic fatty liver disease: evidence and mechanisms of action
Purpose of review Nonalcoholic fatty liver disease (NAFLD) is a highly prevalent progressive cond
Updates in the management of pediatric dyslipidemia
Updates in the management of pediatric dyslipidemia
Purpose of review Pediatric dyslipidemias increase the risk of atherosclerosis and clinical cardi
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