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Assessment of neuropathy subtypes in type 1 diabetes
IntroductionDiabetic polyneuropathy (DPN) is a common complication of diabetes with a lifetime prevalence of up to 50%.1 D...
Plasma sphingolipids mediate the association between gut microbiome composition and type 2 diabetes risk in the HELIUS cohort: a case-cohort study
WHAT IS ALREADY KNOWN ON THIS TOPICThe gut microbiome has been recognized to contribute to type 2 diabetes risk, underlyin...
Effects of insonification on repairing the renal injury of diabetic nephropathy rats
IntroductionDiabetic nephropathy (DN) is a prevalent complication of diabetes and a significant contributor to end-stage r...
Changes in use and hospital outcomes of bariatric surgery in Spain (2016-2022): analysis of the role of type 2 diabetes using propensity score matching
IntroductionIn recent decades, the prevalence of both type 2 diabetes mellitus (T2DM) and obesity has increased progressiv...
Early screening for foot problems in people with diabetes is the need of the hour: 'Save the Feet and Keep Walking Campaign in India
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSThis study gave a broader insight into the burden of foot problems ...
Cardiovascular disease risk factors and their associations with inflammation among US adolescents: NHANES, 2015 to March 2020
WHAT IS ALREADY KNOWN ON THIS TOPICObesity, elevated glucose, hypertension and hyperlipidemia are risk factors for cardiov...
Impact of mitigating obesity, smoking, and physical inactivity on type 2 diabetes mellitus burden in Oman: insights from mathematical modeling
IntroductionType 2 diabetes mellitus (T2DM) remains one of the fastest-growing global health epidemics of the 21st century...
Risk of healthcare visits from influenza in subjects with diabetes and impacts of early vaccination
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSIn this retrospective cohort, patients with diabetes in Louisiana, ...
Metabolic features of neutrophilic differentiation of HL-60 cells in hyperglycemic environments
IntroductionPatients with type 2 diabetes suffer from increased susceptibility to infections, partly a direct consequence ...
Real-world study of the multimorbidity and health service utilisation among individuals with non-diabetic hyperglycemia and type 2 diabetes mellitus in North West London
WHAT IS ALREADY KNOWN ON THIS TOPICNon-diabetic hyperglycemia (NDH) represents a pre-diabetic state, with blood sugar high...
Rate and risk factors of kidney function decline among South Asians with type 2 diabetes: analysis of the CARRS Trial
IntroductionDiabetes is a leading cause of chronic kidney disease (CKD), and the coexistence of these conditions multiplie...
Combined impact of heat and dust on diabetes hospitalization in Kuwait
WHAT IS ALREADY KNOWN ON THIS TOPICThere is a high prevalence of diabetes and obesity in Kuwait, accompanied by severe env...
Adipose tissue-derived adipsin marks human aging in non-type 2 diabetes population
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSOur research revealed that in individuals with diabetes, plasma adi...
Glucokinase activators and imeglimin: new weaponry in the armamentarium against type 2 diabetes
The latest class of antidiabetic drugs, SGLT2 inhibitors, was launched >10 years ago. However, there remains a very gre...
Increased incidence of neurodegenerative diseases in Finnish individuals with type 1 diabetes
IntroductionThe life expectancy of individuals with type 1 diabetes has improved in recent years. In the Pittsburgh Epidem...
Development of a three-dimensional scoring model for the assessment of continuous glucose monitoring data in type 1 diabetes
WHAT IS ALREADY KNOWN ON THIS TOPICContinuous glucose monitoring (CGM) has become an invaluable tool in diabetes managemen...
Not all healthcare inequities in diabetes are equal: a comparison of two medically underserved cohorts
WHAT IS ALREADY KNOWN ON THIS TOPICHealth disparities in diabetes are well documented based on socioeconomic status, race,...
Association between personality, lifestyle behaviors, and cardiovascular diseases in type 2 diabetes mellitus: a population-based cohort study of UK Biobank data
IntroductionThe estimated prevalence of diabetes mellitus (DM) is ~1 per 11 adults worldwide, with the number of individua...
Investigation of end-stage kidney disease risk prediction in an ethnically diverse cohort of people with type 2 diabetes: use of kidney failure risk equation
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYIntroductionChronic kidney dise...
Cardiovascular and mortality benefits of sodium-glucose cotransporter-2 inhibitors and glucagon-like peptide 1 receptor agonists as third-step glucose-lowering medicine in patients with type 2 diabetes: a retrospective cohort analysis
WHAT IS ALREADY KNOWN ON THIS TOPICCurrent guidelines recommend that patients with type 2 diabetes add a third agent when ...
Effects of metformin, saxagliptin and repaglinide on gut microbiota in high-fat diet/streptozocin-induced type 2 diabetic mice
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYIntroductionThe WHO has predict...
Early increase in HbA1c trajectory predicts development of severe microangiopathy in patients with type 1 diabetes: the VISS study
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSAn early increase in HbA1c trajectory strongly predicts the develop...
Multidisciplinary proactive e-consults to improve guideline-directed medical therapies for patients with diabetes and chronic kidney disease: an implementation study
What is already known on this topicProactive e-consults are a novel strategy to implement guideline-directed medical thera...
Eight-year nationwide study of the bidirectional association between type 2 diabetes and depression in nearly 8 million German outpatients
BackgroundType 2 diabetes and depression, both major causes of disability worldwide,1 frequently coexist. According to rec...
Unveiling potential therapeutic targets for diabetes-induced frozen shoulder through Mendelian randomization analysis of the human plasma proteome
WHAT IS ALREADY KNOWN ON THIS TOPICIn recent years, there has been increasing evidence supporting that diabetes may be an ...
Glucose levels measured with continuous glucose monitoring in uncomplicated pregnancies
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYGestational diabetes mellitus (...
Clinical perspectives on the frequency of hypoglycemia in treat-to-target randomized controlled trials comparing basal insulin analogs in type 2 diabetes: a narrative review
IntroductionAs recommended by the American Diabetes Association (ADA) and European Association for the Study of Diabetes (...
Enhancing equity in access to automated insulin delivery systems in an ethnically and socioeconomically diverse group of children with type 1 diabetes
WHAT IS ALREADY KNOWN ON THIS TOPICAutomated insulin delivery (AID) systems have been recognized for enhancing glucose man...
Prospective associations between breast feeding, metabolic health, inflammation and bone density in women with prior gestational diabetes mellitus
WHAT IS ALREADY KNOWN ON THIS TOPICBreastfeeding is a modifiable risk factor for cardiometabolic diseases; however, there ...
Comparing the effectiveness and cost-effectiveness of sulfonylureas and newer diabetes drugs as second-line therapy for patients with type 2 diabetes
IntroductionPharmacologic treatment of type 2 diabetes, along with comprehensive lifestyle modification, typically starts ...
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