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Prevalence and risk factors for skeletal muscle mass loss in individuals with type 1 diabetes
Prevalence and risk factors for skeletal muscle mass loss in individuals with type 1 diabetes
This study aimed to the investigate prevalence and factors associated with reduced skeletal muscle mass in non-elderly adu...
Blood cell HbA1c measured by enzymatic assay show higher than whole blood HbA1c in patients with iron deficiency anemia
Blood cell HbA1c measured by enzymatic assay show higher than whole blood HbA1c in patients with iron deficiency anemia
In Japan, most HbA1c measurements by enzymatic assays or immunoassays represent the HbA1c levels in the blood cell fractio...
Systemic lupus erythematosus and pulmonary tuberculosis in a patient developing acute-onset type 1 diabetes
Systemic lupus erythematosus and pulmonary tuberculosis in a patient developing acute-onset type 1 diabetes
A 73-year-old Japanese woman was admitted to our hospital with anorexia, weight loss, and fever. A few weeks prior to admi...
Practice guideline: Statement regarding treatment for suspected slowly progressive type 1 diabetes (SPIDDM; probable) cases (English Version)
Practice guideline: Statement regarding treatment for suspected slowly progressive type 1 diabetes (SPIDDM; probable) cases (English Version)
Insulin treatment should be introduced in patients with slowly progressive type 1 diabetes (SPIDDM; definite), according t...
Insulin resistant diabetes mellitus in a girl with mild Rabson-Mendenhall syndrome: efficacy of sodium glucose co-transporter 2 inhibitor
Insulin resistant diabetes mellitus in a girl with mild Rabson-Mendenhall syndrome: efficacy of sodium glucose co-transporter 2 inhibitor
We report a beneficial effect of a sodium glucose co-transporter 2 (SGLT2) inhibitor in the management of insulin resistan...
Mitochondrial DNA 3243 mutation may be associated with positivity of zinc transporter 8 autoantibody in cases of slowly progressive type 1 diabetes mellitus
Mitochondrial DNA 3243 mutation may be associated with positivity of zinc transporter 8 autoantibody in cases of slowly progressive type 1 diabetes mellitus
Slowly progressive type 1 diabetes mellitus (SPIDDM), solely positive for zinc transporter 8 autoantibody (ZnT8A) is rare,...
Glycemic variability and quality of life outcomes after changing to hybrid closed-loop system in Japanese individuals with type 1 diabetes using a conventional predictive low-glucose suspended insulin pump system
Glycemic variability and quality of life outcomes after changing to hybrid closed-loop system in Japanese individuals with type 1 diabetes using a conventional predictive low-glucose suspended insulin pump system
The hybrid closed-loop (HCL) system, Medtronic MiniMed™ 770G, has been available for use by Japanese individuals wit...
Differentiation, reduction, and proliferation of pancreatic β-cells and their regulatory factors
Differentiation, reduction, and proliferation of pancreatic β-cells and their regulatory factors
The prevalence of diabetes has increased rapidly in recent years, and many types of therapeutic agents have been developed...
Protective effect of CK2 against endoplasmic reticulum stress in pancreatic β cells
Protective effect of CK2 against endoplasmic reticulum stress in pancreatic β cells
Endoplasmic reticulum (ER) stress due to obesity or systemic insulin resistance is an important pathogenic factor that cou...
Regulation of glucose metabolism by incretins: implications for treatment of type 2 diabetes
Regulation of glucose metabolism by incretins: implications for treatment of type 2 diabetes
Gastrointestinal hormones that potentiate insulin secretion from pancreatic β-cells are called incretins. Glucose-dep...
Long-term effects of esaxerenone in patients with type 2 diabetes, diabetic kidney disease, and hypertension (JDDM77)
Long-term effects of esaxerenone in patients with type 2 diabetes, diabetic kidney disease, and hypertension (JDDM77)
This clinical study assessed the three-year, long-term effects of esaxerenone, a non-steroidal aldosterone receptor blocke...
Pathophysiological hallmarks in type 2 diabetes heterogeneity (review)
Pathophysiological hallmarks in type 2 diabetes heterogeneity (review)
The mechanistic complexity in type 2 diabetes (T2DM) is primarily responsible for the degrees of heterogeneity and develop...
Unraveling the pathophysiology of type 2 diabetes with a new selectively bred animal model, the Oikawa-Nagao mouse
Unraveling the pathophysiology of type 2 diabetes with a new selectively bred animal model, the Oikawa-Nagao mouse
Type 2 diabetes (T2D) is a polygenic disease, and the development of animal models by selective breeding is crucial for un...
Identification of herbal drug extracts that promote growth of Akkermansia muciniphila in high-fat diet fed mice
Identification of herbal drug extracts that promote growth of Akkermansia muciniphila in high-fat diet fed mice
Disruption of the gut microbiota causes metabolic dysfunction, and intervention in the gut microbiota has the potential to...
Glycemic control of once-weekly and other administration frequencies for DPP-4 inhibitor in patients with type 2 diabetes: a real-world retrospective cohort study
Glycemic control of once-weekly and other administration frequencies for DPP-4 inhibitor in patients with type 2 diabetes: a real-world retrospective cohort study
To assess the glycemic control of once-weekly (QW) and other administration frequencies for dipeptidyl peptidase-4 inhibit...
A case of congenital hyperinsulinism presenting with diabetes after long-term diazoxide therapy
A case of congenital hyperinsulinism presenting with diabetes after long-term diazoxide therapy
Congenital hyperinsulinism (CHI) is the most common form of persistent hypoglycemia in infants, and diazoxide is the most ...
A large-scale, observational study to investigate the current status of diabetes complication and their prevention in Japan: incidence/risk factors for malignancies during follow-up—JDCP study 11 (English version)
A large-scale, observational study to investigate the current status of diabetes complication and their prevention in Japan: incidence/risk factors for malignancies during follow-up—JDCP study 11 (English version)
In the large-scale, prospective, observational JDCP study, a total of 5944 people with type 2 diabetes (mean age at baseli...
Severe periodontal disease in Japanese patients with high HbA1c levels: a cross-sectional study
Severe periodontal disease in Japanese patients with high HbA1c levels: a cross-sectional study
This study aimed to investigate the relationship between plasma glucose profiles and periodontal disease (PD) severity in ...
Impact of inpatient management of hyperglycemia on peripheral T cell markers in patients with type 2 diabetes
Impact of inpatient management of hyperglycemia on peripheral T cell markers in patients with type 2 diabetes
Immune cell function is impaired in hyperglycemic patients with diabetes but thought to improve with normalization of bloo...
A case of Cushing’s syndrome in a pregnant woman associated with hypertension, hypokalemia, and gestational diabetes mellitus
A case of Cushing’s syndrome in a pregnant woman associated with hypertension, hypokalemia, and gestational diabetes mellitus
We report the case of a 33-year-old woman who was referred to the department of endocrinology and diagnosed with gestation...
Role of the receptor for advanced glycation end products in the severity of SARS-CoV-2 infection in diabetic patients
Role of the receptor for advanced glycation end products in the severity of SARS-CoV-2 infection in diabetic patients
Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is a severe disease in older adults and in individuals with ass...
Effects of weight loss from oral semaglutide administration on cardiometabolic risk factors in Japanese patients with type 2 diabetes: a retrospective analysis using propensity score matching
Effects of weight loss from oral semaglutide administration on cardiometabolic risk factors in Japanese patients with type 2 diabetes: a retrospective analysis using propensity score matching
Obesity is increasingly being recognized as a chronic disease that exacerbates type 2 diabetes and its related complicatio...
'DKD' as the kidney disease relevant to individuals with diabetes
'DKD' as the kidney disease relevant to individuals with diabetes
Even though chronic kidney disease (CKD) is a significant comorbidity in individuals with diabetes, there appears to be wo...
Elevated urinary albumin predicts increased time in range after initiation of SGLT2 inhibitors in individuals with type 1 diabetes on sensor-augmented pump therapy
Elevated urinary albumin predicts increased time in range after initiation of SGLT2 inhibitors in individuals with type 1 diabetes on sensor-augmented pump therapy
We aimed to investigate potential predictors of effectiveness of SGLT2 inhibitors (SGLT2i) in individuals with type 1 diab...
Impact of hyperglycemia on immune cell function: a comprehensive review
Impact of hyperglycemia on immune cell function: a comprehensive review
Hyperglycemia, a hallmark of diabetes and various metabolic disorders, has profound implications for immune cell function....
Questionnaire survey on severe hypoglycemia in pediatric patients with diabetes-English version
Questionnaire survey on severe hypoglycemia in pediatric patients with diabetes-English version
A questionnaire survey on severe hypoglycemia (SH) in pediatric patients with diabetes was distributed to pediatric diabet...
Diurnal variation in the association between the scan frequency of isCGM and CGM metrics: post hoc analysis of the ISCHIA study
Diurnal variation in the association between the scan frequency of isCGM and CGM metrics: post hoc analysis of the ISCHIA study
To investigate the association between the frequency of intermittent-scanning continuous glucose monitoring (isCGM) and di...
Rapid improvement of severe fatty liver in a case of fulminant type 1 diabetes following insulin treatment
Rapid improvement of severe fatty liver in a case of fulminant type 1 diabetes following insulin treatment
A 36-year-old woman presented to the emergency room with a consciousness disorder after developing abdominal pain with dia...
Influence of diet and body weight in treatment-resistant acquired partial lipodystrophy after hematopoietic stem cell transplantation and its potential for metabolic improvement
Influence of diet and body weight in treatment-resistant acquired partial lipodystrophy after hematopoietic stem cell transplantation and its potential for metabolic improvement
Lipodystrophy is a rare disease characterized by various metabolic complications resulting from the complete or partial lo...
Association between glycemic control and patient-reported outcomes in adults with type 1 diabetes in Japan: the SAGE study subanalysis
Association between glycemic control and patient-reported outcomes in adults with type 1 diabetes in Japan: the SAGE study subanalysis
Psychosocial aspects and the quality of life (QOL) of individuals with diabetes are important for achieving glycemic contr...
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