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Chronic Kidney Disease-Mineral and Bone Disorder Management in 4D: The Case for Dynamic Treatment Regime Methods to Optimize Care
Chronic Kidney Disease-Mineral and Bone Disorder Management in 4D: The Case for Dynamic Treatment Regime Methods to Optimize Care
Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD) is a complex condition impacting patients with kidney failure a...
Emerging Roles of Eosinophils in Bone
Emerging Roles of Eosinophils in Bone
Eosinophils are traditionally known for their role in immune defense against parasites and their involvement in various im...
Potential of Kefir-Derived Peptides, Probiotics, and Exopolysaccharides for Osteoporosis Management
Potential of Kefir-Derived Peptides, Probiotics, and Exopolysaccharides for Osteoporosis Management
Osteoporosis is a prevalent skeletal disorder in postmenopausal women and older adults. Kefir has gained attention for its...
Laboratory-based Biomarkers for Risk Prediction, Auxiliary Diagnosis and Post-operative Follow-up of Osteoporotic Fractures
Laboratory-based Biomarkers for Risk Prediction, Auxiliary Diagnosis and Post-operative Follow-up of Osteoporotic Fractures
Osteoporosis (OP) is characterized by degraded bone microstructure, loss of bone mass and increased risk of fragility frac...
Exercise for Postmenopausal Bone Health – Can We Raise the Bar?
Exercise for Postmenopausal Bone Health – Can We Raise the Bar?
This review summarises the latest evidence on effects of exercise on falls prevention, bone mineral density (BMD) and frag...
Role of Canonical and Non-Canonical Sphingolipids and their Metabolic Enzymes in Bone Health
Role of Canonical and Non-Canonical Sphingolipids and their Metabolic Enzymes in Bone Health
This review summarizes the recently published scientific evidence regarding the role of enzymes engaged in de novo anaboli...
CCN Proteins as Matricellular Regulators of Bone in Aging and Disease
CCN Proteins as Matricellular Regulators of Bone in Aging and Disease
This review explores the role of cell communication network (CCN) proteins in regulating skeletal physiology, aging, and d...
Bridging Genomic Research Disparities in Osteoporosis GWAS: Insights for Diverse Populations
Bridging Genomic Research Disparities in Osteoporosis GWAS: Insights for Diverse Populations
Genome-wide association studies (GWAS) have significantly advanced osteoporosis research by identifying genetic loci assoc...
Treatment of Osteoporosis in Patients with Chronic Kidney Disease
Treatment of Osteoporosis in Patients with Chronic Kidney Disease
To discuss current evidence on the diagnosis and management of osteoporosis in patients with chronic kidney disease (CKD)....
Epigenetic Control of Osteogenesis: Pathways Toward Improved Bone Regeneration
Epigenetic Control of Osteogenesis: Pathways Toward Improved Bone Regeneration
In this review, we summarize our evolving understanding of the epigenetic mechanisms directing the osteogenic differentiat...
Oxygen Sensing in Osteocytes: From Physiology to Age-related Osteoporosis
Oxygen Sensing in Osteocytes: From Physiology to Age-related Osteoporosis
The purpose of this review article is to discuss how oxygen sensing mechanisms regulate the expression of key osteocyte ma...
The Role of Osteoporosis in Total Hip Arthroplasty Periprosthetic Fractures and Current Management Strategies: a Review
The Role of Osteoporosis in Total Hip Arthroplasty Periprosthetic Fractures and Current Management Strategies: a Review
This review provides a background on osteoporosis, describes the relationship between osteoporosis and periprosthetic frac...
Changes in Periprosthetic Bone Mineral Density Following Arthroplasty: An In-Depth Review and Current Perspectives
Changes in Periprosthetic Bone Mineral Density Following Arthroplasty: An In-Depth Review and Current Perspectives
Arthroplasty (e.g., TKA, UKA, THA) is a gold-standard treatment for end-stage joint diseases, yet it often leads to peripr...
Disparities in the Diagnosis and Treatment of Osteoporosis in Persons with Cognitive Impairment and Dementia
Disparities in the Diagnosis and Treatment of Osteoporosis in Persons with Cognitive Impairment and Dementia
The purpose of this review is to summarize recently published scientific evidence (from January 1, 2020-January 1, 2025), ...
Falls in People with Type 1 Diabetes: A Review of Prevalence, Risk Factors, and Preventive Strategies
Falls in People with Type 1 Diabetes: A Review of Prevalence, Risk Factors, and Preventive Strategies
This review aims to summarize recent literature on the prevalence, risk factors, and prevention strategies for falls in pe...
A Fragile Phosphate/Pyrophosphate Balance: From Essential Mineralization to Rare Calcifying Diseases
A Fragile Phosphate/Pyrophosphate Balance: From Essential Mineralization to Rare Calcifying Diseases
Calcification, the deposition of phosphate-calcium crystals, is essential for the development and function of mineralized ...
Ageing-Related Changes in Ultrastructural Bone Matrix Composition and Osteocyte Mechanosensitivity
Ageing-Related Changes in Ultrastructural Bone Matrix Composition and Osteocyte Mechanosensitivity
Bone matrix is a multiscale composite material mainly composed of collagen, crystalline apatite mineral, water, and a smal...
Associations Among Estrogens, the Gut Microbiome and Osteoporosis
Associations Among Estrogens, the Gut Microbiome and Osteoporosis
The purpose of this Review was to summarize the evidence on the associations among estrogen status, cellular senescence, t...
Role of Chemokines and Cytokines in Prostate Cancer Skeletal Metastasis
Role of Chemokines and Cytokines in Prostate Cancer Skeletal Metastasis
Once prostate cancer (PCa) bone metastases develop, the prognosis dramatically declines. The precise mechanisms regulating...
Association Between Air Pollution and Osteoporosis with High-Risk Populations: A Narrative Review
Association Between Air Pollution and Osteoporosis with High-Risk Populations: A Narrative Review
Air pollution has been raised as a novel risk factor for osteoporosis, which impose a huge burden on both individuals and ...
3D Analysis of Tooth Movement Using 3D Technology
3D Analysis of Tooth Movement Using 3D Technology
3D cone beam imaging (CBCT) has allowed clinicians to better understand the anatomical variations of cranial anatomy. One ...
Lignans from Sambucus williamsii Protect Bone Via Microbiome
Lignans from Sambucus williamsii Protect Bone Via Microbiome
Traditional Chinese Medicine has a unique system to diagnose and treat bone diseases with symptoms similar to those of ost...
Between a Rock and a Short Place—The Impact of Nephrolithiasis on Skeletal Growth and Development Across the Lifespan
Between a Rock and a Short Place—The Impact of Nephrolithiasis on Skeletal Growth and Development Across the Lifespan
The impact of nephrolithiasis on skeletal growth and bone health across the life span of kidney stone formers is reviewed....
Extra-osseous Roles of the RANK-RANKL-OPG Axis with a Focus on Skeletal Muscle
Extra-osseous Roles of the RANK-RANKL-OPG Axis with a Focus on Skeletal Muscle
This review aims to consolidate recent observations regarding extra-osseous roles of the RANK-RANKL-OPG axis, primarily wi...
Vitamin D Level Between Calcium-Phosphorus Homeostasis and Immune System: New Perspective in Osteoporosis
Vitamin D Level Between Calcium-Phosphorus Homeostasis and Immune System: New Perspective in Osteoporosis
Vitamin D is a key molecule in calcium and phosphate homeostasis; however, increasing evidence has recently shown that it ...
Vitamin D-Do Diet Recommendations for Health Remain Strong?
Vitamin D-Do Diet Recommendations for Health Remain Strong?
How will the scientific community and authoritative bodies define future nutritional requirements for vitamin D? At the In...
Adiposity and Mineral Balance in Chronic Kidney Disease
Adiposity and Mineral Balance in Chronic Kidney Disease
Bone homeostasis is balanced between formation and resorption activities and remain in relative equilibrium. Under disease...
Lateral Compression Fragility Fractures of the Pelvis: Diagnosis, Classifications, and Modern Management
Lateral Compression Fragility Fractures of the Pelvis: Diagnosis, Classifications, and Modern Management
To describe the diagnosis, classification, and modern management of lateral compression fragility fractures of the pelvis....
Dairy and Exercise for Bone Health: Evidence from Randomized Controlled Trials and Recommendations for Future Research
Dairy and Exercise for Bone Health: Evidence from Randomized Controlled Trials and Recommendations for Future Research
To examine evidence from randomized controlled trials (RCTs) on how modifiable factors such as exercise and nutrition, wit...
PET/CT for the Opportunistic Screening of Osteoporosis and Fractures in Cancer Patients
PET/CT for the Opportunistic Screening of Osteoporosis and Fractures in Cancer Patients
In this review, we outline the different etiologies of osteoporosis in the oncologic setting and describe the basis for us...
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