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Prognostic value of total, free and lipoprotein fraction-bound plasma mitotane levels in advanced adrenocortical carcinoma: a prospective study of the ENDOCAN-COMETE-Cancer network
Prognostic value of total, free and lipoprotein fraction-bound plasma mitotane levels in advanced adrenocortical carcinoma: a prospective study of the ENDOCAN-COMETE-Cancer network
Mitotane is the only approved treatment for metastatic adrenocortical carcinoma (ACC). Monitoring plasma levels is recomme...
Nutritional aspects in neuroendocrine neoplasms. bridging the gap between dietary interventions and cancer care strategies: a scoping review
Nutritional aspects in neuroendocrine neoplasms. bridging the gap between dietary interventions and cancer care strategies: a scoping review
Neuroendocrine neoplasms (NENs) represent heterogeneous tumors arising from neuroendocrine cells in different organs. Desp...
ccfDNA analysis for the classification of adrenocortical adenomas
ccfDNA analysis for the classification of adrenocortical adenomas
Somatic alterations are commonly observed in adrenocortical adenomas including cortisol-producing (CPA) [overt Cushing syn...
Was the painter’s model for Hercules an acromegalic giant?
Was the painter’s model for Hercules an acromegalic giant?
Conflict of interest The authors declare no competing inter...
The role of TMEM163 protein in thyroid microcarcinoma: expression pattern and clinical implications
The role of TMEM163 protein in thyroid microcarcinoma: expression pattern and clinical implications
TMEM163 protein is a new zinc ion transporter whose regulatory role in tumors has yet to be discovered. This study aimed t...
A single bout of physical exercise improves 1-hour post-load plasma glucose in healthy young adults
A single bout of physical exercise improves 1-hour post-load plasma glucose in healthy young adults
Physical exercise is a key component in the treatment of type 2 diabetes and plays an important role in maintaining a heal...
Pannexin-1 regulation of ATP release promotes the invasion of pituitary adenoma
Pannexin-1 regulation of ATP release promotes the invasion of pituitary adenoma
Pannexin-1 (PANX1) channel participates in the development and progression of many tumor types, however, its role of PANX1...
Prevalence, risk factors and effect of curative parathyroidectomy on nephrocalcinosis in Asian-Indian patients with symptomatic primary hyperparathyroidism
Prevalence, risk factors and effect of curative parathyroidectomy on nephrocalcinosis in Asian-Indian patients with symptomatic primary hyperparathyroidism
Primary hyperparathyroidism (PHPT) is characterized by inappropriate secretion of parathyroid hormone, causing hypercalcem...
Accelerated biological aging, mediating amino acids, and risk of incident type 2 diabetes: a prospective cohort study
Accelerated biological aging, mediating amino acids, and risk of incident type 2 diabetes: a prospective cohort study
Aging plays an important role in type 2 diabetes mellitus (T2DM). But the association between accelerated biological age a...
Assessment of aortomesenteric distance and mesenteric and retroperitoneal adipose tissue thickness in genetic forms of lipodystrophy
Assessment of aortomesenteric distance and mesenteric and retroperitoneal adipose tissue thickness in genetic forms of lipodystrophy
Lipodystrophy is a rare disease characterized by the loss of adipose tissue. Visceral adipose tissue loss in certain forms...
Growth hormone replacement therapy enhances humoral response to COVID-19 mRNA vaccination in patients with adult-onset growth hormone deficiency
Growth hormone replacement therapy enhances humoral response to COVID-19 mRNA vaccination in patients with adult-onset growth hormone deficiency
Given the established link between GH/insulin-like growth factor 1 (IGF-1) deficiency and severe COVID-19 outcomes, this r...
Thyroxine overuse and clinical indices guiding successful treatment withdrawal
Thyroxine overuse and clinical indices guiding successful treatment withdrawal
Levothyroxine (LT4) is commonly prescribed, but there is evidence strongly suggesting that a significant proportion of the...
Morphometric vertebral fractures at hospitalization associate with Long COVID occurrence
Morphometric vertebral fractures at hospitalization associate with Long COVID occurrence
Long COVID is a multisystemic syndrome leading to significant morbidity. To date, a comprehensive characterization of unde...
Exploring the interplay of karyotype, hormones, sexuality, and body image perception in individuals with Turner syndrome
Exploring the interplay of karyotype, hormones, sexuality, and body image perception in individuals with Turner syndrome
Most patients with Turner Syndrome (TS) require Hormone Replacement Therapy (HRT). Androgen levels could be compromised du...
MiR-27a-5p inhibits malignant progression of differentiated thyroid cancer by directly affecting the miR-27a-5p/SREBP1 axis
MiR-27a-5p inhibits malignant progression of differentiated thyroid cancer by directly affecting the miR-27a-5p/SREBP1 axis
To detect the expression of miR-27a-5p in differentiated thyroid cancer (DTC) and to explore its correlation with SREBP1 e...
Evaluation of fluid status in patients with acromegaly through bioelectrical impedance vector analysis: a cross-sectional study
Evaluation of fluid status in patients with acromegaly through bioelectrical impedance vector analysis: a cross-sectional study
The acromegalic state is associated with an increase in total body water and sodium. The aim of our study was to assess th...
An objective way to predict remission and relapse in Cushing disease using Bayes’ theorem of probability
An objective way to predict remission and relapse in Cushing disease using Bayes’ theorem of probability
In this study on patients with Cushing disease, post-transsphenoidal surgery (TSS), we attempt to predict the probability ...
Development of diagnostic algorithm for Cushing’s syndrome: a tertiary centre experience
Development of diagnostic algorithm for Cushing’s syndrome: a tertiary centre experience
No consensus exists as the gold standard for Cushing’s Syndrome (CS) screening. This study aimed to evaluate the dia...
Endocrine disruptors, aryl hydrocarbon receptor and cortisol secretion
Endocrine disruptors, aryl hydrocarbon receptor and cortisol secretion
Endocrine disruptors exert a plethora of effects in endocrine tissues, from altered function to carcinogenesis. Given its ...
Authorship of Italian medical literature on neuroendocrine neoplasms: any gender gap?
Authorship of Italian medical literature on neuroendocrine neoplasms: any gender gap?
While males have dominated the physician lines over the last decades the recent female doctors’ number increasing mi...
JPT2 in subclinical hypothyroidism-related miscarriage as a transcription co-factor: involvement of LEPR/STAT3 activation
JPT2 in subclinical hypothyroidism-related miscarriage as a transcription co-factor: involvement of LEPR/STAT3 activation
Subclinical hypothyroidism (SCH) has been identified to be associated with implantation failure, in which the dysfunction ...
Rachel score: a nomogram model for predicting the prognosis of lung neuroendocrine tumors
Rachel score: a nomogram model for predicting the prognosis of lung neuroendocrine tumors
Lung NET, classified in typical carcinoids (TC) and atypical carcinoids (AC), are highly heterogeneous in their biology an...
The need for the GREAT+ score to predict relapse in Graves’ disease: a questionnaire among patients and internal medicine specialists
The need for the GREAT+ score to predict relapse in Graves’ disease: a questionnaire among patients and internal medicine specialists
Graves’ disease (GD) is an auto-immune cause of hyperthyroidism. First-line treatment often consists of a 12–1...
Sodium-glucose cotransporter 2 inhibitors and cancer: a systematic review and meta-analysis
Sodium-glucose cotransporter 2 inhibitors and cancer: a systematic review and meta-analysis
The effect of sodium–glucose cotransporter 2 (SGLT2) inhibitors on cancer has yet to be fully elucidated. This syste...
Development of a diagnostic model for pre-washout screening of primary aldosteronism
Development of a diagnostic model for pre-washout screening of primary aldosteronism
Primary aldosteronism (PA) diagnosis is affected by antihypertensive drugs that are commonly taken by patients with suspec...
Endocrinology application of molecular imaging: current role of PET/CT
Endocrinology application of molecular imaging: current role of PET/CT
In recent years, nuclear medicine imaging methods have proven to be of paramount importance in a wide variety of diseases,...
Evaluation of pituitary function and metabolic parameters in patients with traumatic maxillofacial fractures
Evaluation of pituitary function and metabolic parameters in patients with traumatic maxillofacial fractures
This study was designed to assess the pituitary functions of patients with traumatic maxillofacial fractures and compare t...
Mouse model of Graves’ orbitopathy induced by the immunization with TSHR A and IGF-1R α subunit gene
Mouse model of Graves’ orbitopathy induced by the immunization with TSHR A and IGF-1R α subunit gene
The study aimed to establish a mouse model of Graves’ disease (GD) with Graves’ orbitopathy (GO; GD +...
Sculptures with goiter in the Ossuccio Sacred Mount: when pathognomonic signs have a specific moral significance
Sculptures with goiter in the Ossuccio Sacred Mount: when pathognomonic signs have a specific moral significance
Conflict of interest The authors declare no competing inter...
Increased risk of erythrocytosis in men with type 2 diabetes treated with combined sodium-glucose cotransporter-2 inhibitor and testosterone replacement therapy
Increased risk of erythrocytosis in men with type 2 diabetes treated with combined sodium-glucose cotransporter-2 inhibitor and testosterone replacement therapy
In clinical trials, sodium-glucose cotransporter-2 inhibitors (SGLT-2i) and testosterone replacement therapy (TRT) were sh...
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