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Iron homeostasis and insulin sensitivity: unraveling the complex interactions
Iron homeostasis and insulin sensitivity: unraveling the complex interactions
Diabetes has arisen as a noteworthy global health issue, marked by escalating incidence and mortality rates. Insulin, cruc...
Growth hormone – releasing hormone in the immune system
Growth hormone – releasing hormone in the immune system
GHRH is a neuropeptide associated with a diverse variety of activities in human physiology and immune responses. The prese...
Clinical research progress on β-cell dysfunction in T2DM development in the Chinese population
Clinical research progress on β-cell dysfunction in T2DM development in the Chinese population
The prevalence of type-2 diabetes mellitus (T2DM) has increased over 10-fold in the past 40 years in China, which now has ...
A novel approach for the treatment of AML, through GHRH antagonism: MIA-602
A novel approach for the treatment of AML, through GHRH antagonism: MIA-602
Acute myeloid leukemia (AML) is the most aggressive and prevalent form of leukemia in adults. The gold-standard interventi...
The molecular basis of hypoprolactinaemia
The molecular basis of hypoprolactinaemia
Hypoprolactinaemia is an endocrinopathy which is typically encountered as part of a combined pituitary hormone deficiency ...
Growth hormone-releasing hormone and cancer
Growth hormone-releasing hormone and cancer
The hypothalamic hormone growth hormone-releasing hormone (GHRH), in addition to promoting the synthesis and release of gr...
Meal replacements on obesity and leptin: a systematic review and meta-analysis
Meal replacements on obesity and leptin: a systematic review and meta-analysis
The global prevalence of obesity and overweight is a significant concern in the field of public health. Numerous intervent...
GHRH and its analogues in central nervous system diseases
GHRH and its analogues in central nervous system diseases
Growth hormone-releasing hormone (GHRH) is primarily produced by the hypothalamus and stimulates the release of growth hor...
Prolactin: structure, receptors, and functions
Prolactin: structure, receptors, and functions
Prolactin (PRL) is a 23-kDa protein synthesized and secreted by lactotroph cells of the anterior pituitary gland but also ...
Role of HOXA10 in pathologies of the endometrium
Role of HOXA10 in pathologies of the endometrium
HOXA10 belongs to the homeobox gene family and is essential for uterine biogenesis, endometrial receptivity, embryo implan...
GHRH and the prostate
GHRH and the prostate
In the late 1960s and early 1970s, hypothalamic regulatory hormones were isolated, characterized and sequenced. Later, it ...
Androgen deficiency in hypopituitary women: its consequences and management
Androgen deficiency in hypopituitary women: its consequences and management
Women with hypopituitarism have various degrees of androgen deficiency, which is marked among those with combined hypogona...
New insights on diagnosis and treatment of AVP deficiency
New insights on diagnosis and treatment of AVP deficiency
Arginine vasopressin deficiency (AVP-D) is one of the main entities of the polyuria-polydipsia syndrome. Its correct diagn...
Morbidities and mortality among hospitalized patients with hypopituitarism: Prevalence, causes and management
Morbidities and mortality among hospitalized patients with hypopituitarism: Prevalence, causes and management
Hypopituitarism is a highly heterogeneous multisystem disorder that can have a major impact on long-term morbidity and mor...
Special features on insulin resistance, metabolic syndrome and vascular complications in hypopituitary patients
Special features on insulin resistance, metabolic syndrome and vascular complications in hypopituitary patients
Pituitary hormone deficiency, hypopituitarism, is a dysfunction resulting from numerous etiologies, which can be complete ...
Diagnosing and treating anterior pituitary hormone deficiency in pediatric patients
Diagnosing and treating anterior pituitary hormone deficiency in pediatric patients
Hypopituitarism, or the failure to secrete hormones produced by the anterior pituitary (adenohypophysis) and/or to release...
Diagnosing and treating the elderly individual with hypopituitarism
Diagnosing and treating the elderly individual with hypopituitarism
Hypopituitarism in the elderly is an underestimated condition mainly due to the non-specific presentation that can be attr...
Evidence-based definition of hypoprolactinemia in European men aged 40–86 years: the European male ageing study
Evidence-based definition of hypoprolactinemia in European men aged 40–86 years: the European male ageing study
Empirical evidence for a low normal or reference interval for serum prolactin (PRL) is lacking for men, while the implicat...
Inhibitors of apolipoprotein C3, triglyceride levels, and risk of pancreatitis: a systematic review and meta-analysis
Inhibitors of apolipoprotein C3, triglyceride levels, and risk of pancreatitis: a systematic review and meta-analysis
In recent years, novel apoC3 inhibitor therapies for the treatment of hypertriglyceridemia have been developed and assesse...
Subclinical central hypothyroidism in patients with hypothalamic-pituitary disease: does it exist?
Subclinical central hypothyroidism in patients with hypothalamic-pituitary disease: does it exist?
Central hypothyroidism (CH) is characterized by decreased thyroid hormone production due to insufficient stimulation of an...
The changing landscape of acromegaly – an epidemiological perspective
The changing landscape of acromegaly – an epidemiological perspective
Acromegaly is a rare disease and thus challenging to accurately quantify epidemiologically. In this comprehensive literatu...
Diagnosis and management of secondary adrenal crisis
Diagnosis and management of secondary adrenal crisis
Adrenal crisis (AC) is a life threatening acute adrenal insufficiency (AI) episode which can occur in patients with primar...
Endocrine involvement in hepatic glycogen storage diseases: pathophysiology and implications for care
Endocrine involvement in hepatic glycogen storage diseases: pathophysiology and implications for care
Hepatic glycogen storage diseases constitute a group of disorders due to defects in the enzymes and transporters involved ...
Correction to: Potential therapeutic strategies for osteoarthritis via CRISPR/Cas9 mediated gene editing
Correction to: Potential therapeutic strategies for osteoarthritis via CRISPR/Cas9 mediated gene editing
Cite this articleVlashi, R., Zhang, X., Li, H. et al. Correction to: Potential therapeutic strategies for osteoarthritis v...
The effect of bariatric surgery on the expression of gastrointestinal taste receptors: A systematic review
The effect of bariatric surgery on the expression of gastrointestinal taste receptors: A systematic review
Gastrointestinal nutrient sensing via taste receptors may contribute to weight loss, metabolic improvements, and a reduced...
Pulling the trigger: Noncoding RNAs in white adipose tissue browning
Pulling the trigger: Noncoding RNAs in white adipose tissue browning
White adipose tissue (WAT) serves as the primary site for energy storage and endocrine regulation in mammals, while brown ...