SCI Abstract

search
+
Zebrafish Models for Skeletal and Extraskeletal Osteogenesis Imperfecta Features: Unveiling Pathophysiology and Paving the Way for Drug Discovery
Zebrafish Models for Skeletal and Extraskeletal Osteogenesis Imperfecta Features: Unveiling Pathophysiology and Paving the Way for Drug Discovery
In the last decades, the easy genetic manipulation, the external fertilization, the high percentage of homology with human...
Preventing OsteoPorosis in Spinal Cord Injury (POPSCI) Study—Early Zoledronic Acid Infusion in Patients with Acute Spinal Cord Injury
Preventing OsteoPorosis in Spinal Cord Injury (POPSCI) Study—Early Zoledronic Acid Infusion in Patients with Acute Spinal Cord Injury
Accelerated sub-lesional bone loss is common in the first 2–3 years after traumatic spinal cord injury (TSC...
MTX Osteopathy Versus Osteoporosis Including Response to Treatment Data—A Retrospective Single Center Study Including 172 Patients
MTX Osteopathy Versus Osteoporosis Including Response to Treatment Data—A Retrospective Single Center Study Including 172 Patients
MTX is an effective and widely used immunomodulatory drug for rheumatoid diseases. MTX osteopathy is a very rare and speci...
Effect of Fibroblast Growth Factor (FGF) 19 and 21 on Hip Geometry and Strength in Post-menopausal Osteoporosis (PMO)
Effect of Fibroblast Growth Factor (FGF) 19 and 21 on Hip Geometry and Strength in Post-menopausal Osteoporosis (PMO)
Fibroblast Growth Factor (FGF) receptor signalling is important for skeletal development. The FGF19 subfamily which includ...
Causes of Musculoskeletal Pain in Paget’s Disease of Bone
Causes of Musculoskeletal Pain in Paget’s Disease of Bone
Paget’s disease of bone (PDB) is characterised by increased and disorganised bone remodelling leading to various com...
Muscle Performance as a Predictor of Bone Health: Among Community-Dwelling Postmenopausal Japanese Women from Setagaya-Aoba Study
Muscle Performance as a Predictor of Bone Health: Among Community-Dwelling Postmenopausal Japanese Women from Setagaya-Aoba Study
Osteoporosis is a significant health concern for postmenopausal women, necessitating efficient screening methods for bone ...
Evaluation of the Nordic Musculoskeletal Questionnaire for Measuring Prevalence and the Consequence of Pain in a Danish Adult OI Population: A Pilot Study
Evaluation of the Nordic Musculoskeletal Questionnaire for Measuring Prevalence and the Consequence of Pain in a Danish Adult OI Population: A Pilot Study
Pain is a challenge in persons with OI and causes much concern in the Osteogenesis Imperfecta (OI) population. We aim to e...
Association Between Dietary Acid Load and Grip Strength in Adults 50 Years and Older: A Cross-Sectional Study
Association Between Dietary Acid Load and Grip Strength in Adults 50 Years and Older: A Cross-Sectional Study
Minimal data exist on whether the acid–base balance of the diet is linked to muscle strength. The aim of th...
The Characteristics of Gut Microbiota and Its Relation with Diet in Postmenopausal Osteoporosis
The Characteristics of Gut Microbiota and Its Relation with Diet in Postmenopausal Osteoporosis
The gut microbiome is linked to osteoporosis. Previous clinical studies showed inconsistent results. This study aimed to c...
Evaluation of Potential Roles of Zinc Finger Homeobox 3 (Zfhx3) Expressed in Chondrocytes and Osteoblasts on Skeletal Growth in Mice
Evaluation of Potential Roles of Zinc Finger Homeobox 3 (Zfhx3) Expressed in Chondrocytes and Osteoblasts on Skeletal Growth in Mice
Bone formation is tightly modulated by genetically encoded molecular proteins that interact to regulate cellular different...
Developing Cut-off Values for Low and Very Low Bone Mineral Density at the Thoracic Spine Using Quantitative Computed Tomography
Developing Cut-off Values for Low and Very Low Bone Mineral Density at the Thoracic Spine Using Quantitative Computed Tomography
Osteoporosis is under-diagnosed while detectable by measuring bone mineral density (BMD) using quantitative computer tomog...
Influence of Menstrual Cycle and Oral Contraceptive Phases on Bone (re)modelling Markers in Response to Interval Running
Influence of Menstrual Cycle and Oral Contraceptive Phases on Bone (re)modelling Markers in Response to Interval Running
To explore how sex hormone fluctuations may affect bone metabolism, this study aimed to examine P1NP and β-CTX-1 conc...
The Relationship between Sclerostin and Kidney Transplantation Mineral Bone Disorders: A Molecule of Controversies
The Relationship between Sclerostin and Kidney Transplantation Mineral Bone Disorders: A Molecule of Controversies
Kidney transplantation is the most effective treatment option for most patients with end-stage kidney disease due to reduc...
Exogenous Angiotensin-(1–7) Provides Protection Against Inflammatory Bone Resorption and Osteoclastogenesis by Inhibition of TNF-α Expression in Macrophages
Exogenous Angiotensin-(1–7) Provides Protection Against Inflammatory Bone Resorption and Osteoclastogenesis by Inhibition of TNF-α Expression in Macrophages
Renin–angiotensin–aldosterone system plays a crucial role in the regulation of blood pressure and fluid homeos...
3D U-Net Neural Network Architecture-Assisted LDCT to Acquire Vertebral Morphology Parameters: A Vertebral Morphology Comprehensive Analysis in a Chinese Population
3D U-Net Neural Network Architecture-Assisted LDCT to Acquire Vertebral Morphology Parameters: A Vertebral Morphology Comprehensive Analysis in a Chinese Population
To evaluate the feasibility of acquiring vertebral height from chest low-dose computed tomography (LDCT) images using an a...
Short-Term Changes in Bone Metabolism Among Transgender Men Starting Gender-Affirming Hormone Therapy: A Systematic Review and Meta-analysis
Short-Term Changes in Bone Metabolism Among Transgender Men Starting Gender-Affirming Hormone Therapy: A Systematic Review and Meta-analysis
Transgender and gender diverse individuals experience a gender identity that differs from the sex assigned at birth. Some ...
Biochemical Clusters as Substitutes of Bone Biopsies in Kidney Transplant Patients
Biochemical Clusters as Substitutes of Bone Biopsies in Kidney Transplant Patients
Bone and mineral metabolism abnormalities are frequent in kidney transplant recipients and have been associated with cardi...
Changes in Blood Pressure is Associated with Bone Loss in US Adults: A Cross-Sectional Study from NHANES 2005–2018
Changes in Blood Pressure is Associated with Bone Loss in US Adults: A Cross-Sectional Study from NHANES 2005–2018
Hypertension and osteoporosis are common geriatric diseases, sharing similar risk factors. This study aims to investigate ...
Identification of a Novel Homozygous Missense Mutation in the CLDN16 Gene to Decipher the Ambiguous Clinical Presentation Associated with Autosomal Dominant Hypocalcaemia and Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis in an Indian Family
Identification of a Novel Homozygous Missense Mutation in the CLDN16 Gene to Decipher the Ambiguous Clinical Presentation Associated with Autosomal Dominant Hypocalcaemia and Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis in an Indian Family
Familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHNNC) is a rare autosomal recessive renal tubulopathy d...
Effect of Roflumilast, a Selective PDE4 Inhibitor, on Bone Phenotypes in ADO2 Mice
Effect of Roflumilast, a Selective PDE4 Inhibitor, on Bone Phenotypes in ADO2 Mice
Autosomal Dominant Osteopetrosis type II (ADO2) is a rare bone disease of impaired osteoclastic bone resorption that usual...
Osteosarcopenia: Prevalence and 10-Year Fracture and Mortality Risk – A Longitudinal, Population-Based Study of 75-Year-Old Women
Osteosarcopenia: Prevalence and 10-Year Fracture and Mortality Risk – A Longitudinal, Population-Based Study of 75-Year-Old Women
Osteosarcopenia is the coexistence of low bone mass and sarcopenia. In older women, its prevalence is not well described, ...
Comparison of the Clinical Outcomes of Vesselplasty vs. Percutaneous Vertebroplasty for the Treatment of Neurologically Intact Osteoporotic Kümmell’s Disease: A Retrospective Study
Comparison of the Clinical Outcomes of Vesselplasty vs. Percutaneous Vertebroplasty for the Treatment of Neurologically Intact Osteoporotic Kümmell’s Disease: A Retrospective Study
Kummell’s disease (KD) is a rare clinical complication of osteoporotic vertebral compression fractures (OVCFs). Mini...
The Effect of Rheumatoid Arthritis on Features Associated with Sarcopenia: A Mendelian Randomization Study
The Effect of Rheumatoid Arthritis on Features Associated with Sarcopenia: A Mendelian Randomization Study
Previous epidemiological evidence suggests rheumatoid arthritis is associated with sarcopenia-related features. However, m...
Regulatory Pathways in Growth Plate Chondrocytes that Are Impacted by Matrix Vesicle microRNA Identified by Targeted RISC Pulldown and Sequencing of the Resulting Transcriptome
Regulatory Pathways in Growth Plate Chondrocytes that Are Impacted by Matrix Vesicle microRNA Identified by Targeted RISC Pulldown and Sequencing of the Resulting Transcriptome
During endochondral bone formation, growth plate chondrocytes are differentially regulated by various factors and hormones...
Trend and Seasonality of Hip Fractures in Catalonia, Spain: Exploring the Influence of Climate
Trend and Seasonality of Hip Fractures in Catalonia, Spain: Exploring the Influence of Climate
To describe the secular trend and seasonality of the incidence of hip fracture (HF) and its relationship with climatic var...
Lipid Metabolism, Methylation Aberrant, and Osteoporosis: A Multi-omics Study Based on Mendelian Randomization
Lipid Metabolism, Methylation Aberrant, and Osteoporosis: A Multi-omics Study Based on Mendelian Randomization
Observational studies have shown a causal association between dyslipidemia and osteoporosis, but the genetic causation and...
An Additional Lrp4 High Bone Mass Mutation Mitigates the Sost-Knockout Phenotype in Mice by Increasing Bone Remodeling
An Additional Lrp4 High Bone Mass Mutation Mitigates the Sost-Knockout Phenotype in Mice by Increasing Bone Remodeling
Pathogenic variants disrupting the binding between sclerostin (encoded by SOST) and its receptor LRP4 have previously been...
The Association Between SHBG and Osteoporosis: A NHANES Cross-Sectional Study and A Bidirectional Mendelian Randomization
The Association Between SHBG and Osteoporosis: A NHANES Cross-Sectional Study and A Bidirectional Mendelian Randomization
This study aimed to examine the association between sex hormone-binding globulin (SHBG) and osteoporosis through a cross-s...
Coenzyme Q10 Protects Against Hyperlipidemia-Induced Osteoporosis by Improving Mitochondrial Function via Modulating miR-130b-3p/PGC-1α Pathway
Coenzyme Q10 Protects Against Hyperlipidemia-Induced Osteoporosis by Improving Mitochondrial Function via Modulating miR-130b-3p/PGC-1α Pathway
In hyperlipidemia-induced osteoporosis, bone marrow mesenchymal stem cells (BMSCs) differentiate into more adipocytes than...
A Critical Review of Current Worldwide Definitions of Sarcopenia
A Critical Review of Current Worldwide Definitions of Sarcopenia
With the increasing number of elderly individuals worldwide, the prevalence of age-related loss of muscle mass, referred t...
Load More
format_indent_increase