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SGLT-2 inhibitors: Diabetes and CKD and CHF (and gout?), oh my!
SGLT-2 inhibitors: Diabetes and CKD and CHF (and gout?), oh my!
Hyperglycemia is the hallmark characteristic of diabetes mellitus. Blood glucose and hemoglobin A1c are guideline-driven m...
Severe hyponatremia: Are you monitoring the urine output?
Severe hyponatremia: Are you monitoring the urine output?
To the Editor: We read with great interest the article by Bassil and colleagues1 on severe hyponatremia in the April issue...
In Reply: Severe hyponatremia: Are you monitoring the urine output?
In Reply: Severe hyponatremia: Are you monitoring the urine output?
We appreciate the letter from Drs. Katyal and Joshi regarding our Symptoms to Diagnosis article.1They point out 2 recent s...
Varicose veins
Varicose veins
A 60-year-old man weighing 154 lb (70 kg) presented to his primary care physician with a 20-year history of slowly worseni...
Do patients with sepsis benefit from intravenous albumin?
Do patients with sepsis benefit from intravenous albumin?
My hospitalized adult patient with sepsis is hypotensive despite adequate resuscitation with intravenous (IV) crystalloid ...
SGLT-2 inhibitors in heart failure and chronic kidney disease: A review for internists
SGLT-2 inhibitors in heart failure and chronic kidney disease: A review for internists
Heart failure and chronic kidney disease are common diseases that lead to considerable morbidity and mortality.1–3 Modern ...
Does my patient with acute variceal hemorrhage need a transjugular intrahepatic portosystemic shunt?
Does my patient with acute variceal hemorrhage need a transjugular intrahepatic portosystemic shunt?
A 48-year-old man with a history of alcohol-associated cirrhosis presents with hematemesis. His Model for End-stage Liver ...
Preventing herpes zoster in immunocompromised patients: Current concepts
Preventing herpes zoster in immunocompromised patients: Current concepts
ABSTRACTHerpes zoster (HZ) incidence is much higher in immunocompromised individuals than in immunocompetent individuals. ...
Lymphedema vs lipedema: Similar but different
Lymphedema vs lipedema: Similar but different
ABSTRACTLymphedema and lipedema are chronic debilitating disorders that most commonly affect the upper and lower extremiti...
A tale of scale: Corticosteroids and pustular psoriasis
A tale of scale: Corticosteroids and pustular psoriasis
In this issue of the Journal, Wong and colleagues1 describe a severe episode of generalized pustular psoriasis (GPP) in a ...
2023 Update in ambulatory general internal medicine
2023 Update in ambulatory general internal medicine
To the Editor: I am writing to express my gratitude for the insightful article “2023 Update in ambulatory general internal...
In Reply: 2023 Update in ambulatory general internal medicine
In Reply: 2023 Update in ambulatory general internal medicine
We appreciate Ashley Lim’s close read of our review. Regarding the use of SGLT-2 inhibitors in patients without albuminuri...
Steroid use triggers severe psoriatic reaction
Steroid use triggers severe psoriatic reaction
A 69-year-old man with well-controlled plaque psoriasis who presented to the emergency department for unilateral wrist pai...
Is there a role for chronic suppressive therapy in herpes simplex virus infection?
Is there a role for chronic suppressive therapy in herpes simplex virus infection?
Yes. The primary role of chronic suppressive therapy in herpes simplex virus (HSV) infection is to decrease the frequency,...
Medical management of benign prostatic hyperplasia
Medical management of benign prostatic hyperplasia
ABSTRACTMedical management of benign prostatic hyperplasia (BPH) has progressed gradually in recent years and remains the ...
Multiple metabolic renal manifestations of a systemic disease
Multiple metabolic renal manifestations of a systemic disease
A 39-year-old woman with a history of depression, anxiety, and recurrent nephrolithiasis with calcium phosphate and calciu...
Hematologic complications after kidney and pancreas transplant in a patient with chronic myeloid leukemia
Hematologic complications after kidney and pancreas transplant in a patient with chronic myeloid leukemia
A 35-year-old woman with a history of type 1 diabetes mellitus, diabetic retinopathy, and end-stage renal disease secondar...
Artificial intelligence in clinical practice: A look at ChatGPT
Artificial intelligence in clinical practice: A look at ChatGPT
In the rapidly evolving landscape of healthcare technologies, the integration of artificial intelligence in clinical pract...
Why I, as a rheumatologist, am happy to make the diagnosis of obstructive sleep apnea
Why I, as a rheumatologist, am happy to make the diagnosis of obstructive sleep apnea
In this issue of the Journal, Aboussouan and his multidisciplinary coauthors1 review available treatment options for patie...
Oral lichen planus
Oral lichen planus
A 36-year-old male presented with lesions over the lips and the left buccal mucosa for the past 6 months. The lesions were...
Stiff hands in a man with type 1 diabetes
Stiff hands in a man with type 1 diabetes
A 23-year-old man with type 1 diabetes presented with stiffness in both hands that had progressively worsened over the pre...
Should my patients take their blood pressure medications in the evening to enhance cardiovascular benefit?
Should my patients take their blood pressure medications in the evening to enhance cardiovascular benefit?
No. Although the cardiovascular benefits of controlled blood pressure (BP) are clear,1 current evidence is insufficient to...
Hey, Doc: Could the 2023-2024 cold and flu season finally be the calm after the storm?
Hey, Doc: Could the 2023-2024 cold and flu season finally be the calm after the storm?
The 2023–2024 cold and flu season is the first in history in which we’re armed with vaccines against the 3 currently most ...
Contemporary surgical and procedural management of benign prostatic hyperplasia
Contemporary surgical and procedural management of benign prostatic hyperplasia
ABSTRACTInterventions for benign prostatic hyperplasia have evolved from transurethral resection of the prostate and simpl...
The drop of a pin: Accidental ingestion of a sharp foreign body
The drop of a pin: Accidental ingestion of a sharp foreign body
A 36-year-old female presented to the emergency department following foreign body ingestion. Thirty minutes before arrival...
Treatments for obstructive sleep apnea: CPAP and beyond
Treatments for obstructive sleep apnea: CPAP and beyond
Continuous positive airway pressure (CPAP) remains the gold standard treatment for obstructive sleep apnea, but it is not ...
Anchors away
Anchors away
Before you read this, please read the article by Prakash et al,1 part of our Symptoms to Diagnosis series.The Journal has ...
A reticular eruption on the thighs
A reticular eruption on the thighs
A 17-year-old girl presented to our dermatology clinic with a 2-month history of an asymptomatic reticular rash on both th...
Is the MTHFR gene mutation associated with thrombosis?
Is the MTHFR gene mutation associated with thrombosis?
Polymorphisms of the methylene tetrahydrofolate reductase (MTHFR) gene are common among the general population, and data f...
What is the role for terlipressin in hepatorenal syndrome?
What is the role for terlipressin in hepatorenal syndrome?
With careful patient selection, terlipressin, a synthetic analogue of vasopressin, is an effective therapy for hepatorenal...
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