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Call to improve transparent communication in direct-to-consumer test marketing
Call to improve transparent communication in direct-to-consumer test marketing
All tests ‘(…) do harm; some do good as well, and, of these, some do more good than harm at reasonable cost.’ Muir Gray an...
Reducing low value care: opportunities and challenges for Choosing Wisely campaigns
Reducing low value care: opportunities and challenges for Choosing Wisely campaigns
Low value care harms patients (due to adverse events of treatments or secondary unwarranted tests), overburdens healthcare...
Making sustainable healthcare decisions: three turns towards sustainable guidelines
Making sustainable healthcare decisions: three turns towards sustainable guidelines
Over time, an international consensus on ‘best practice’ for developing a range of guidelines has been reached in many are...
Open access journal publication in health and medical research and open science: benefits, challenges and limitations
Open access journal publication in health and medical research and open science: benefits, challenges and limitations
Scientific progress, including in evidence-based medicine, requires all available evidence to be accessed, scrutinised, in...
Adherence to the Guideline for Reporting Evidence-based practice Educational interventions and Teaching (GREET) of studies on evidence-based healthcare e-learning: a cross-sectional study
Adherence to the Guideline for Reporting Evidence-based practice Educational interventions and Teaching (GREET) of studies on evidence-based healthcare e-learning: a cross-sectional study
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Genetic predisposition, modifiable lifestyles, and their joint effects on human lifespan: evidence from multiple cohort studies
Genetic predisposition, modifiable lifestyles, and their joint effects on human lifespan: evidence from multiple cohort studies
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Trivalent and quadrivalent seasonal influenza vaccine in adults aged 60 and older: a systematic review and network meta-analysis
Trivalent and quadrivalent seasonal influenza vaccine in adults aged 60 and older: a systematic review and network meta-analysis
WHAT IS ALREADY KNOWN ON THIS TOPICSeasonal influenza vaccination of older adults (≥60 years old) is an important societal...
Rapid review methods series: Guidance on the use of supportive software
Rapid review methods series: Guidance on the use of supportive software
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSThis paper presents an overview of considerations and recommendatio...
Preventing overdiagnosis and overuse: proposed guidance for guideline panels
Preventing overdiagnosis and overuse: proposed guidance for guideline panels
Moving from evidence to recommendations, guideline panels can influence decisions in everyday clinical practice. Consequen...
Survey of US physicians attitudes and knowledge of AI
Survey of US physicians attitudes and knowledge of AI
IntroductionArtificial intelligence (AI) applications in healthcare have proliferated over the past several years.1 Potent...
Teaching to address overdiagnosis
Teaching to address overdiagnosis
The whole art of medicine is in observation… but to educate the eye to see, the ear to hear and the finger to feel takes t...
Ethical implications of AI-driven bias assessment in medicine
Ethical implications of AI-driven bias assessment in medicine
Barsby et al present a thought-provoking pilot study which discusses the application of large language models (LLMs) for a...
Decision architecture randomisation: extremely efficient clinical trials that preserve clinician and patient choice?
Decision architecture randomisation: extremely efficient clinical trials that preserve clinician and patient choice?
Healthcare is full of choices between standard-of-care approaches where one might be better but we do not know which. Exam...
The Six Steps of SDM: linking theory to practice, measurement and implementation
The Six Steps of SDM: linking theory to practice, measurement and implementation
Shared decision-making (SDM) has gained acceptance as a preferred and ideal method for medical decision-making.1 2 As SDM ...
Towards transparency: adoption of WHO best practices in clinical trial registration and reporting among top medical research funders in the USA
Towards transparency: adoption of WHO best practices in clinical trial registration and reporting among top medical research funders in the USA
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Patient-reported effects of hospital-wide implementation of shared decision-making at a university medical centre in Germany: a pre-post trial
Patient-reported effects of hospital-wide implementation of shared decision-making at a university medical centre in Germany: a pre-post trial
IntroductionShared decision-making (SDM) is considered the apex of patient-centred, evidence-based healthcare. Much has be...
Does the format of result presentation and type of conclusion in Cochrane plain language summaries matter? A randomised controlled trial
Does the format of result presentation and type of conclusion in Cochrane plain language summaries matter? A randomised controlled trial
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Catalogue of bias: racial bias
Catalogue of bias: racial bias
Racial bias is a distortion arising from systemic, institutional, interpersonal or individual forms of explicit (conscious...
Introduction of allergenic food to infants and allergic and autoimmune conditions: a systematic review and meta-analysis
Introduction of allergenic food to infants and allergic and autoimmune conditions: a systematic review and meta-analysis
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Reducing the residue of retractions in evidence synthesis: ways to minimise inappropriate citation and use of retracted data
Reducing the residue of retractions in evidence synthesis: ways to minimise inappropriate citation and use of retracted data
WHAT IS ALREADY KNOWN ON THIS TOPICWHAT THIS STUDY ADDSAuthors, editors, publishers, research institutions, funding agenci...
Visualisation of evidence for shared decision making
Visualisation of evidence for shared decision making
Why does it matter?Consistent with the principles of evidence-based medicine, effectively communicating evidence (includin...
Talk to me, but rather: talk to each other
Talk to me, but rather: talk to each other
During a yearly routine check-up for my alopecia in a hospital on the other side of the country, a small cancerous mass wa...
When does the placebo effect have an impact on network meta-analysis results?
When does the placebo effect have an impact on network meta-analysis results?
IntroductionMany definitions have been proposed for placebo, from ‘a medicine given more to please than to benefit’ in the...
Dynamic intervention strategies await inclusion in clinical evidence synthesis
Dynamic intervention strategies await inclusion in clinical evidence synthesis
In the first half of this year, an article about the next generation of evidence-based medicine1 was published in Nature  ...
Is a one-size-fits-all '12-month rule appropriate when it comes to the last search date in systematic reviews?
Is a one-size-fits-all '12-month rule appropriate when it comes to the last search date in systematic reviews?
SRs are a recognised research approach for identifying, synthesising and analysing published evidence on topics of interes...
Expanding the measurement of overdiagnosis in the context of disease precursors and risk factors
Expanding the measurement of overdiagnosis in the context of disease precursors and risk factors
Because individual patients weigh benefits and harms differently, it is important to provide quantitative information abou...
Living health technology assessments: how close to living reality?
Living health technology assessments: how close to living reality?
IntroductionHealthcare decision-makers are exploring more responsive, innovative processes in the wake of the COVID-19 pan...
Detection bias in open-label trials of anticancer drugs: a meta-epidemiological study
Detection bias in open-label trials of anticancer drugs: a meta-epidemiological study
are validated by studies that overcome this limitation, it is desirable to establish central reviewers in oncological open...
Piloting a new method to estimate action thresholds in medicine through intuitive weighing
Piloting a new method to estimate action thresholds in medicine through intuitive weighing
IntroductionThe threshold approach in clinical decision-makingWhen confronted with diagnostic uncertainty clinicians will ...
Re-evaluating the role of pilot trials in informing effect and sample size estimates for full-scale trials: a meta-epidemiological study
Re-evaluating the role of pilot trials in informing effect and sample size estimates for full-scale trials: a meta-epidemiological study
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