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A review on advancements in feature selection and feature extraction for high-dimensional NGS data analysis
A review on advancements in feature selection and feature extraction for high-dimensional NGS data analysis
Recent advancements in biomedical technologies and the proliferation of high-dimensional Next Generation Sequencing (NGS) ...
QTL-seq identifies genomic region associated with the crown root development under Jasmonic acid response
QTL-seq identifies genomic region associated with the crown root development under Jasmonic acid response
Rice root system plays a crucial role in plant adaptation under adverse conditions, particularly drought stress. However, ...
Regulatory axis of circular RNA DTNB, microRNA-485-5p, and myeloid cell leukemia 1 attenuates inflammation and apoptosis in caerulein-treated AR42J cells
Regulatory axis of circular RNA DTNB, microRNA-485-5p, and myeloid cell leukemia 1 attenuates inflammation and apoptosis in caerulein-treated AR42J cells
Acute pancreatitis (AP) is an inflammatory disease of the pancreas and the main cause of hospital admissions for gastroint...
Whole-genome sequencing and identification of antimicrobial peptide coding genes in parsley (Petroselinum crispum), an important culinary and medicinal Apiaceae species
Whole-genome sequencing and identification of antimicrobial peptide coding genes in parsley (Petroselinum crispum), an important culinary and medicinal Apiaceae species
Parsley is a commonly cultivated Apiaceae species of culinary and medicinal importance. Parsley has several recognized hea...
Infection by a multidrug-resistant Corynebacterium diphtheriae strain: prediction of virulence factors, CRISPR-Cas system analysis, and structural implications of mutations conferring rifampin resistance
Infection by a multidrug-resistant Corynebacterium diphtheriae strain: prediction of virulence factors, CRISPR-Cas system analysis, and structural implications of mutations conferring rifampin resistance
Cases of diphtheria, even in immunized individuals, are still reported in several parts of the world, including in Brazil....
Application of single cell sequencing technology in ovarian cancer research (review)
Application of single cell sequencing technology in ovarian cancer research (review)
Ovarian cancer is a malignant tumor of ovary. It has the characteristics of difficult early diagnosis, poor late curative ...
Clinical trials and recent progress in HIV vaccine development
Clinical trials and recent progress in HIV vaccine development
The greatest obstacle for scientists is to develop an effective HIV vaccine. An effective vaccine represents the last hope...
Signaling molecules in the microenvironment of hepatocellular carcinoma
Signaling molecules in the microenvironment of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a major fatal cancer that is known for its high recurrence and metastasis. An increasing...
Modulatory effects of miRNAs in doxorubicin resistance: A mechanistic view
Modulatory effects of miRNAs in doxorubicin resistance: A mechanistic view
MicroRNAs (miRNAs) are a group of small non-coding RNAs and play an important role in controlling vital biological process...
Integrative analyses of long and short-read RNA sequencing reveal the spliced isoform regulatory network of seedling growth dynamics in upland cotton
Integrative analyses of long and short-read RNA sequencing reveal the spliced isoform regulatory network of seedling growth dynamics in upland cotton
The polyploid genome of cotton has significantly increased the transcript complexity. Recent advances in full-length trans...
Biotechnological frontiers in harnessing allelopathy for sustainable crop production
Biotechnological frontiers in harnessing allelopathy for sustainable crop production
Allelopathy, the phenomenon in which plants release biochemical compounds that influence the growth and development of nei...
Genetic diversity and evolution of G12P[6] DS-1-like and G12P[9] AU-1-like Rotavirus strains in Brazil
Genetic diversity and evolution of G12P[6] DS-1-like and G12P[9] AU-1-like Rotavirus strains in Brazil
In the early 2000s, the global emergence of rotavirus (RVA) G12P[8] genotype was noted, while G12P[6] and G12P[9] combinat...
Circular RNAs: a small piece in the heart failure puzzle
Circular RNAs: a small piece in the heart failure puzzle
Cardiovascular disease, specifically heart failure (HF), remains a significant concern in the realm of healthcare, necessi...
Identification of flowering genes in Camellia perpetua by comparative transcriptome analysis
Identification of flowering genes in Camellia perpetua by comparative transcriptome analysis
Camellia perpetua has the excellent characteristic of flowering multiple times throughout the year, which is of great impo...
Knockdown of ADAMDEC1 ameliorates ox-LDL-induced endothelial cell injury and atherosclerosis progression
Knockdown of ADAMDEC1 ameliorates ox-LDL-induced endothelial cell injury and atherosclerosis progression
This study was designed to investigate the role of a disintegrin and metalloproteinase domain-like protein decysin 1 (ADAM...
Hypoxia-induced circRTN4IP1 promotes progression and glycolysis of hepatocellular carcinoma cells
Hypoxia-induced circRTN4IP1 promotes progression and glycolysis of hepatocellular carcinoma cells
Hypoxia is one of the hallmarks of solid tumors, especially in hepatocellular carcinoma (HCC). CircRNAs are reported to be...
IGF2 is upregulated by its antisense RNA to potentiate pancreatic cancer progression
IGF2 is upregulated by its antisense RNA to potentiate pancreatic cancer progression
Pancreatic cancer is a deadly cancer. More and more long noncoding RNAs (lncRNAs) have received confirmation to be dysregu...
Benchmarking of bioinformatics tools for NGS-based microRNA profiling with RT-qPCR method
Benchmarking of bioinformatics tools for NGS-based microRNA profiling with RT-qPCR method
MicroRNAs are vital gene expression regulators, extensively studied worldwide. The large-scale characterization of miRNAom...
CFAP61 knockdown aggravates male infertility by inhibiting testosterone secretion by Leydig cells via the MAPK/COX-2 pathway
CFAP61 knockdown aggravates male infertility by inhibiting testosterone secretion by Leydig cells via the MAPK/COX-2 pathway
This study aimed to elucidate the roles of cilia- and flagella-associated protein 61 (CFAP61) in male infertility and its ...
3′-tRF-CysGCA overexpression in HEK-293 cells alters the global expression profile and modulates cellular processes and pathways
3′-tRF-CysGCA overexpression in HEK-293 cells alters the global expression profile and modulates cellular processes and pathways
tRNA fragments (tRFs) are small non-coding RNAs generated through specific cleavage of tRNAs and involved in various biolo...
NLRP3/miR-223-3p axis attenuates neuroinflammation induced by chronic intermittent hypoxia
NLRP3/miR-223-3p axis attenuates neuroinflammation induced by chronic intermittent hypoxia
Obstructive sleep apnea (OSA) is mainly characterized by chronic intermittent hypoxia (CIH) with multiple brain injuries. ...
The cellular trajectories of tumor-associated macrophages decipher the heterogeneity of pancreatic cancer
The cellular trajectories of tumor-associated macrophages decipher the heterogeneity of pancreatic cancer
Emerging evidence indicates that the interactions and dynamic changes among tumor-associated macrophages (TAMs) are pivota...
Comparative transcriptome analysis reveals candidate genes related to the sex differentiation of Schisandra chinensis
Comparative transcriptome analysis reveals candidate genes related to the sex differentiation of Schisandra chinensis
Schisandra chinensis is a monoecious plant with unisex flowers. The fruit of S. chinensis is of high medical with economic...
Combining single-cell RNA sequencing data and transcriptomic data to unravel potential mechanisms and signature genes of the progression of idiopathic pulmonary fibrosis to lung adenocarcinoma and predict therapeutic agents
Combining single-cell RNA sequencing data and transcriptomic data to unravel potential mechanisms and signature genes of the progression of idiopathic pulmonary fibrosis to lung adenocarcinoma and predict therapeutic agents
Patients with idiopathic pulmonary fibrosis (IPF) have a significantly higher prevalence of lung adenocarcinoma (LUAD) tha...
Nrf2 attenuates oxidative stress to mediate the protective effect of ciprofol against cerebral ischemia–reperfusion injury
Nrf2 attenuates oxidative stress to mediate the protective effect of ciprofol against cerebral ischemia–reperfusion injury
Neuroinflammation and oxidative stress damage are involved in the pathogenesis of cerebral ischemia–reperfusion inju...
Validating post-enrichment steps in environmental RNA analysis for improving its availability from water samples
Validating post-enrichment steps in environmental RNA analysis for improving its availability from water samples
Environmental RNA (eRNA) analysis is expected to inclusively provide the physiological information of a population and com...
Meta-analysis of transcriptomics studies identifies novel attributes and set of genes involved in iron homeostasis in rice
Meta-analysis of transcriptomics studies identifies novel attributes and set of genes involved in iron homeostasis in rice
Iron (Fe) is an important micronutrient for humans as well as for plant growth and development. Rice employs multiple mech...
Long noncoding RNA LINC00482 silencing sensitizes non-small cell lung cancer cells to cisplatin by downregulating CLASRP via E2F1
Long noncoding RNA LINC00482 silencing sensitizes non-small cell lung cancer cells to cisplatin by downregulating CLASRP via E2F1
Long noncoding RNA LINC00482 (LINC00482) is dysregulated in non-small cell lung cancer cells (NSCLC). Herein, this researc...
Novel insights into molecular signatures and pathogenic cell populations shared by systemic lupus erythematosus and vascular dementia
Novel insights into molecular signatures and pathogenic cell populations shared by systemic lupus erythematosus and vascular dementia
Although vascular dementia (VD) and systemic lupus erythematosus (SLE) may share immune-mediated pathophysiologic processe...
Mitochondria-related lncRNAs: predicting prognosis, tumor microenvironment and treatment response in lung adenocarcinoma
Mitochondria-related lncRNAs: predicting prognosis, tumor microenvironment and treatment response in lung adenocarcinoma
Lung cancer is the most common type of malignant tumor that affects people in China and even across the globe, as it exhib...
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