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Diversity of human skin three-dimensional organotypic cultures
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Cell–cell interactions between transplanted retinal organoid cells and recipient tissues
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Circuit integration by transplanted human neurons
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Control of cell fate upon transcription factor–driven cardiac reprogramming
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Unveiling the potential: implications of successful somatic cell-to-ganglion organoid reprogramming
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The power of proximity: mechanisms and biological roles of transvection
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Genome folding and zygotic genome activation in mammalian preimplantation embryos
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Better together: how cooperativity influences transcriptional bursting
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Emerging interactions between RNA methylation and chromatin architecture
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Editorial overview: Epitranscriptomics: Exploring a new frontier in health and disease
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Strategies for programmable manipulation of alternative splicing
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Editorial overview: Drivers, droplets, and deeds of nuclear genome organization
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Archaic hominin admixture and its consequences for modern humans
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Novelty versus innovation of gene regulatory elements in human evolution and disease
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Inferring human phenotypes using ancient DNA: from molecules to populations
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Genetic factors mediating long-range enhancer–promoter communication in mammalian development
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In vitro dynamics of DNA loop extrusion by structural maintenance of chromosomes complexes
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Roles of intrinsically disordered protein regions in transcriptional regulation and genome organization
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Nuclear remodeling during cell fate transitions
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Early central nervous system development and neuron regeneration
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Timers, variability, and body-wide coordination: C. elegans as a model system for whole-animal developmental timing
Timers, variability, and body-wide coordination: C. elegans as a model system for whole-animal developmental timing
Successful development requires both precise timing of cellular processes, such as division and differentiation, and tight...
Toward a comprehensive view of gene architecture during transcription
Toward a comprehensive view of gene architecture during transcription
In multicellular organisms, the same genetic code gives rise to a large diversity of cell types. A fully stretched out ver...
The influencers' era: how the environment shapes chromatin in 3D
The influencers' era: how the environment shapes chromatin in 3D
Environment–epigenome interactions are emerging as contributors to disease risk and health outcomes. In fact, organisms ou...
Inheritance of epigenetic transcriptional memory
Inheritance of epigenetic transcriptional memory
An improved understanding of nuclear architecture has begun to reveal how genome organization affects transcription and ot...
Corrigendum to: “PRC2 accessory factors: rheostats for cell fate decision?” [Curr Opin Genet Dev 84 (2024) 102137]
Corrigendum to: “PRC2 accessory factors: rheostats for cell fate decision?” [Curr Opin Genet Dev 84 (2024) 102137]
Volume 85, April 2024, 102157Author links open overlay panelHina Bharti *, Sungwook Han *, Han-Wen Chang *, Danny Reinberg...
Therapeutic targeting of BET bromodomain and other epigenetic acetylrecognition domain–containing factors
Therapeutic targeting of BET bromodomain and other epigenetic acetylrecognition domain–containing factors
In this perspective, we discuss the emerging class of epigenetic cancer therapies targeting acetylrecognition domain–conta...
Chromatin and aberrant enhancer activity in KMT2A rearranged acute lymphoblastic leukemia
Chromatin and aberrant enhancer activity in KMT2A rearranged acute lymphoblastic leukemia
To make a multicellular organism, genes need to be transcribed at the right developmental stages and in the right tissues....
Mitochondrial metabolism and the continuing search for ultimate regulators of developmental rate
Mitochondrial metabolism and the continuing search for ultimate regulators of developmental rate
A fundamental question in developmental biology is how the pace of developmental processes is controlled from a cell biolo...
Temporal patterning of the vertebrate developing neural tube
Temporal patterning of the vertebrate developing neural tube
scRNAseq data has been obtained from the indicated references (forebrain, midbrain, hindbrain: [34], spinal cord: [31], re...
The significance of ultradian oscillations in development
The significance of ultradian oscillations in development
Embryos develop autonomously under a predetermined schedule. While the genes involved in these processes have been charact...
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