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SCI Abstract
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Skin-Directed Therapies in Mycosis Fungoides: An Update
Mycosis fungoides (MF) is the most common subtype of cutaneous T cell lymphoma (CTCL), characterized by monoclona...
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The Lived Experience of Patients Diagnosed with Vitiligo and a Preliminary Conceptual Disease Model: Insights from Patients, Patient Advocates, and Clinicians
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Efficacy of 5-Fluorouracil 4% Cream in the Treatment of Hyperkeratotic Actinic Keratosis: A Single-Center Retrospective Real-World Study
Actinic keratosis (AK) is recognized as the main precursor of cutaneous squamous cell carcinoma (cSCC). Given the unpredic...
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Cancer Risk in Vitiligo: No Evidence of Increased Prevalence—A Systematic Review and Meta-analysis
Vitiligo, a chronic depigmenting disorder affecting 1–2% of the global population, is caused by immune-mediated mela...
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Prevalence and Association of Autoimmune Comorbidities Among Adults with Vitiligo: A Systematic Literature Review and Meta-analysis of USA-Based Studies
Vitiligo is an autoimmune, depigmenting skin disease affecting 0.1–1.6% of adults in the USA. Despite observed corre...
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Cocaine-Induced Dermatomucositis: Clarifying Diagnostic Controversies and Introducing IgG4 Positivity as a New Histopathological Feature
Cocaine-induced dermatomucositis is a recently described clinical entity with significant controversy regarding its diagno...
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Habitual Scratching in Atopic Dermatitis and Its Association with Disease Severity: Findings from Japanese Health Insurance Claims and App-Based Data
In atopic dermatitis (AD), scratching sustains inflammation and impairs the skin barrier. Beyond scratching driven by itch...
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Acne Conglobata: Understanding This Rare Form of Acne and Management Strategies
Acne conglobata is a severe, often eruptive, form of acne included in the follicular occlusion tetrad along with hidradeni...
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Long-Term Effectiveness and Safety of Bimekizumab in Patients with Moderate to Severe Hidradenitis Suppurativa Under Real Clinical Practice Conditions: The Importance of Combined Treatment in Hurley III Patients and Potential Factors Associated with Complete Response
Hidradenitis suppurativa (HS) is a debilitating, chronic inflammatory skin disease that severely impacts patients’ q...
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Efficacy and Safety of Sarecycline in Chinese Patients with Moderate-to-Severe Acne Vulgaris: Randomized Phase 3 Clinical Trial with Open-Label Follow-Up
This study aimed to evaluate the efficacy and safety of sarecycline in Chinese patients with moderate-to-severe acne vulga...
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The Safety, Tolerability, and Pharmacokinetics of ALT-BB4 (A Novel Recombinant Hyaluronidase): A Randomized, Double-Blinded, Placebo-Controlled, Phase 1 Study in Healthy Volunteers
Hyaluronidase has been used as an adjuvant to facilitate subcutaneous drug delivery by degrading hyaluronic acid, a viscoe...
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Efficacy of Skin Patting and Iontophoresis with Dutasteride Gel in Male and Menopausal Female Androgenetic Alopecia: A Pilot Study
Androgenetic alopecia (AGA) is a chronic, progressive condition often resistant to conventional treatments. Transdermal de...
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Efficacy and Safety of Zabedosertib, an Interleukin-1 Receptor-Associated Kinase 4 Inhibitor, in Patients with Moderate-to-Severe Atopic Dermatitis: A Phase II Randomized Study
Interleukin-1 receptor-associated kinase 4 (IRAK4) is expressed in various immune cells and regulates proinflammatory cyto...
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Strategies for Optimal Use of Biological Therapies in Managing Psoriasis: Focus on Secukinumab
Psoriasis (PsO) is a common inflammatory dermatological condition with a substantial negative impact on patient quality of...
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Network Meta-analysis of 1.5% Ruxolitinib Cream Versus Systemic Agents in the Treatment of Moderate Atopic Dermatitis
Atopic dermatitis (AD) is a chronic, highly pruritic, relapsing inflammatory disease associated with high quality-of-life ...
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A Pilot Study of Differences in Antibody Responses of Intradermal and Intramuscular Injections of Botulinum Toxin Type A
Botulinum toxin type A (BoNT/A) is commonly used for both medical and aesthetic purposes. However, approximately 3% of lon...
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Rocatinlimab: A Novel T-Cell Rebalancing Therapy Targeting the OX40 Receptor in Atopic Dermatitis
Atopic dermatitis (AD) is a chronic inflammatory disease characterized by eczematous skin lesions, intense pruritus, skin ...
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