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Navigating diagnostic dilemmas: a rare presentation of extramedullary T-lymphoblastic leukemia/lymphoma with chronic myeloid leukemia
Navigating diagnostic dilemmas: a rare presentation of extramedullary T-lymphoblastic leukemia/lymphoma with chronic myeloid leukemia
Chronic myeloid leukemia (CML) typically presents in the chronic phase. The blast crisis phase in CML predominantly compri...
BRAF V600E mutation and high expression of PD-L1 in Rosai-Dorfman disease: case report and review of the literature
BRAF V600E mutation and high expression of PD-L1 in Rosai-Dorfman disease: case report and review of the literature
BRAF V600E mutations are frequently found in histiocytic/dendritic cell neoplasms such as Erdheim-Chester disease (ECD) an...
Mast cell sarcoma with  p.D816V mutation and concurrent systemic mastocytosis
Mast cell sarcoma with p.D816V mutation and concurrent systemic mastocytosis
Mast cell sarcoma (MCS) is an extremely rare and aggressive form of mastocytosis characterized by highly atypical mast cel...
Perifollicular concentric granulomas: A clue to IgG4-related lymphadenopathy
Perifollicular concentric granulomas: A clue to IgG4-related lymphadenopathy
A 69-year-old with well-controlled HIV was evaluated for persistent cough, in the context of years of fatigue and...
Primary gastric T-cell lymphoma presenting with perforation: a case report and review of the literature
Primary gastric T-cell lymphoma presenting with perforation: a case report and review of the literature
Primary gastric T-cell lymphomas (PGTL) are exceedingly rare with an estimated incidence of 0.0091 per 100,000 person-year...
A rare case of primary testicular follicular lymphoma in a pediatric patient
A rare case of primary testicular follicular lymphoma in a pediatric patient
Testicular follicular lymphoma (TFL) is an exceedingly rare lymphoma that typically occurs in young male patients and is n...
CD3/CD20/CD45 negative leukemia cutis
CD3/CD20/CD45 negative leukemia cutis
A 56-year-old male presented to the clinic with complaints of multiple skin lesions. A complete blood count (CBC) was not ...
Correction to: CD3/CD20/CD45 negative leukemia cutis
Correction to: CD3/CD20/CD45 negative leukemia cutis
A skin punch biopsy showed fragments of skin with extensive lymphoid infiltrates (Fig.1, A; x20 objective, hematoxylin and...
Diffuse large B-cell lymphoma with partial low Ki67 proliferation index
Diffuse large B-cell lymphoma with partial low Ki67 proliferation index
We present a case of diffuse large B-cell lymphoma characterized by areas exhibiting unexpectedly low Ki67 staining in a 4...
A rare case of multiple myeloma with double translocations: t(11;14) and t(14;16)
A rare case of multiple myeloma with double translocations: t(11;14) and t(14;16)
Multiple myeloma is a clonal plasma cell malignancy often characterized by complex cytogenetic abnormalities that influenc...
Lymph node microscopic findings in Wiskott-Aldrich syndrome
Lymph node microscopic findings in Wiskott-Aldrich syndrome
A 20-year-old man with a history of Wiskott-Aldrich syndrome (WAS) underwent excisional biopsy of a femoral lymph&nbsp...
HLA-DR positive acute promyelocytic leukaemia (APML) with cryptic  fusion
HLA-DR positive acute promyelocytic leukaemia (APML) with cryptic fusion
We report the case of a 42-year-old female presented with cytopenia and abnormal promyelocytes on blood film. The promyelo...
Bridging dermatology and hematology: a case of lepromatous leprosy with bone marrow involvement and pancytopenia
Bridging dermatology and hematology: a case of lepromatous leprosy with bone marrow involvement and pancytopenia
Leprosy, caused by Mycobacterium leprae (M. leprae), primarily manifests with cutaneous and peripheral nerve invo...
Simultaneous merkel cell carcinoma and acute myeloid leukaemia: A diagnostic challenge
Simultaneous merkel cell carcinoma and acute myeloid leukaemia: A diagnostic challenge
Merkel cell carcinoma is a very aggressive primary skin tumour with a high risk of local recurrences and lymphatic and dis...
Complete loss of lineage defining antigens in two cases of B-cell malignancies following CAR-T therapy
Complete loss of lineage defining antigens in two cases of B-cell malignancies following CAR-T therapy
Targeted immunotherapy is a promising approach in treating high-risk and refractory/relapsed lymphoid malignancies. Althou...
Systemic ALK-negative anaplastic large cell lymphoma with NPM1::TYK2 rearrangement
Systemic ALK-negative anaplastic large cell lymphoma with NPM1::TYK2 rearrangement
Anaplastic large cell lymphoma (ALCL) is a rare subtype of non-Hodgkin lymphoma, with most cases harboring ALK gene rearra...
An unusual case of pure erythroid leukemia with normal karyotype and NPM1 mutation
An unusual case of pure erythroid leukemia with normal karyotype and NPM1 mutation
Pure erythroid leukemia (PEL) is an extremely rare subtype of acute myeloid leukemia (AML). Although not specific, PEL is ...
CD8-positive T-cell lymphoproliferative disorder of the uterus: a new subtype of indolent extranodal T-cell neoplasm?
CD8-positive T-cell lymphoproliferative disorder of the uterus: a new subtype of indolent extranodal T-cell neoplasm?
A 51-year-old female with menorrhagia was found to have a cervical polyp. Polypectomy and endometrial curettage showed an ...
Infectious mononucleosis complicated by transitory Epstein-Barr virus infection of T and natural killer cells
Infectious mononucleosis complicated by transitory Epstein-Barr virus infection of T and natural killer cells
Epstein-Barr virus (EBV) typically infects B cells in infectious mononucleosis (IM), but a rare case shows EBV infection i...