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Higher risk of hepatotoxicity associated with cabozantinib in cancer patients
Higher risk of hepatotoxicity associated with cabozantinib in cancer patients
Cabozantinib is a multi-kinase inhibitor with a broad spectrum of anti-tumour activity and immunomodulation (Choueiri et a...
A net-work meta-analysis of the cardiac safety for next-generation hormonal agents in treating castration-resistant prostate cancer: How to choose drugs appropriately?
A net-work meta-analysis of the cardiac safety for next-generation hormonal agents in treating castration-resistant prostate cancer: How to choose drugs appropriately?
The incidence of prostate cancer (PCa) has risen rapidly around the world. Androgen deprivation therapy (ADT) is commonly ...
Efficacy and safety of trastuzumab deruxtecan in treating human epidermal growth factor receptor 2-low/positive advanced breast cancer:A meta-analysis of randomized controlled trials
Efficacy and safety of trastuzumab deruxtecan in treating human epidermal growth factor receptor 2-low/positive advanced breast cancer:A meta-analysis of randomized controlled trials
In 2020, breast cancer replaced lung cancer as the most common cancer worldwide; this cancer type is the leading type of c...
Impact of smoking cessation duration on lung cancer mortality: A systematic review and meta-analysis
Impact of smoking cessation duration on lung cancer mortality: A systematic review and meta-analysis
Mei Jiang, PhD, an expert in epidemiology and evidence-based medicine specializing in the intersection of respiratory dise...
Decoding the puzzle: A multidisciplinary systematic review of adult brainstem glioma
Decoding the puzzle: A multidisciplinary systematic review of adult brainstem glioma
Brainstem gliomas (BSGs) account for approximately 20% of primary tumors of the central nervous system in pediatric patien...
Small extracellular vesicles: multi-functional aspects in non-small cell lung carcinoma
Small extracellular vesicles: multi-functional aspects in non-small cell lung carcinoma
EVs deliver functional molecules through cell-to-cell interaction, and alter physiological and pathological functions of r...
Patient-reported outcomes in randomized clinical trials of systemic therapy for advanced soft tissue sarcomas in adults: a systematic review
Patient-reported outcomes in randomized clinical trials of systemic therapy for advanced soft tissue sarcomas in adults: a systematic review
Olga Husson, PhD. Epidemiologist and associate Group Leader in The Netherlands Cancer Institute focusing on Adolescent and...
Role of Extracellular Vesicles in Castration-Resistant Prostate Cancer
Role of Extracellular Vesicles in Castration-Resistant Prostate Cancer
Bishao Sun#, M.D. Ph.D. Attending physician in the Department of Urology, Urologic Surgery Center, Xinqiao Hospital, Army ...
Prognostic and Therapeutic Potential of STAT3: Opportunities and Challenges in Targeting HPV-Mediated Cervical Carcinogenesis
Prognostic and Therapeutic Potential of STAT3: Opportunities and Challenges in Targeting HPV-Mediated Cervical Carcinogenesis
Cervical cancer (CaCx) stands as a dominant gynecological malignancy on a global scale, with an estimated annual incidence...
Tumor Mutational Burden in Colorectal Cancer: Implications for Treatment
Tumor Mutational Burden in Colorectal Cancer: Implications for Treatment
Bruno Sepodes PharmD, MSc, PhD, MPH. Full Professor of Pharmacology and Pharmacotherapy at the Faculty of Pharmacy Univers...
Potential Therapeutic Targets in Myeloid Cell Therapy for Overcoming Chemoresistance and Immune Suppression in Gastrointestinal Tumors
Potential Therapeutic Targets in Myeloid Cell Therapy for Overcoming Chemoresistance and Immune Suppression in Gastrointestinal Tumors
Gastrointestinal cancers account for over a quarter of all cancer incidence globally and contribute to approximately one-t...
Tertiary prevention strategies for micrometastatic lymph node cervical cancer: A systematic review and a prototype of an adapted model of care
Tertiary prevention strategies for micrometastatic lymph node cervical cancer: A systematic review and a prototype of an adapted model of care
Cervical cancer was the 9th most common cancer in the world in 2020, accounting for approximately 6.4% of new cancer cases...
Circulating biomarkers as predictors of response to immune checkpoint inhibitors in NSCLC: Are we on the right path?
Circulating biomarkers as predictors of response to immune checkpoint inhibitors in NSCLC: Are we on the right path?
Immune checkpoints inhibitors (ICIs) have markedly improved the therapeutic management of advanced NSCLC and, more recentl...
Emerge of colorectal cancer in Lynch syndrome despite colonoscopy surveillance: A challenge of hide and seek
Emerge of colorectal cancer in Lynch syndrome despite colonoscopy surveillance: A challenge of hide and seek
Matthias Kloor is a physician-scientist, deputy director and group lead at the department of Applied Tumor Biology, Heidel...
Sialylated glycoproteins and sialyltransferases in digestive cancers: Mechanisms, diagnostic biomarkers, and therapeutic targets
Sialylated glycoproteins and sialyltransferases in digestive cancers: Mechanisms, diagnostic biomarkers, and therapeutic targets
Sialylation is a process in which sialic acid (SA) epitopes bind to certain saccharides under the catalysis of specific si...
Gut and local microbiota in patients with cancer: increasing evidence and potential clinical applications
Gut and local microbiota in patients with cancer: increasing evidence and potential clinical applications
Recently, the relationship between cancer, microbiota, and oncologic treatments, especially immunotherapy, has raised the ...
Multi-disciplinary management of esophageal carcinoma: Current practices and future directions
Multi-disciplinary management of esophageal carcinoma: Current practices and future directions
Chanyoot Bandidwattanawong is the Associate Professor in Medical Oncology at Division of Medical Oncology, Department of I...
Crosstalk between hypoxia-induced pyroptosis and immune escape in cancer: From mechanisms to therapy
Crosstalk between hypoxia-induced pyroptosis and immune escape in cancer: From mechanisms to therapy
Michael R. Hamblin: was Principal Investigator at the Wellman Center for Photomedicine at Massachusetts General Hospital, ...
The risk of breast cancer and gynecologic malignancies after ovarian stimulation: Meta-analysis of cohort study
The risk of breast cancer and gynecologic malignancies after ovarian stimulation: Meta-analysis of cohort study
For decades, the use of ovarian stimulation continues to increase with the number of infertile population (Skakkebaek et a...
A systematic review and meta-analysis of the effectiveness of primary thromboprophylaxis in acute lymphoblastic leukemia during early-phase therapy including asparaginase or its prolonged form
A systematic review and meta-analysis of the effectiveness of primary thromboprophylaxis in acute lymphoblastic leukemia during early-phase therapy including asparaginase or its prolonged form
Acute lymphoblastic leukemia (ALL), the most common type of childhood cancer, has cure rates exceeding 90% among pediatric...
KRAS G12C-mutant driven non-small cell lung cancer (NSCLC)
KRAS G12C-mutant driven non-small cell lung cancer (NSCLC)
Available online 9 December 2023, 104228Author links open overlay panel, , , , , , , , , , HIGHLIGHTS•KRAS G12C mutations ...
Clinical relevance of exosome-derived microRNAs in Ovarian Cancer: Looking for new tumor biological fingerprints
Clinical relevance of exosome-derived microRNAs in Ovarian Cancer: Looking for new tumor biological fingerprints
Ovarian cancer (OC) represents the most frequent gynecological malignancy, accounting for the seventh most common female t...
Natural Killer Cells at the Forefront of Cancer Immunotherapy with Immune Potency, Genetic Engineering, and Nanotechnology
Natural Killer Cells at the Forefront of Cancer Immunotherapy with Immune Potency, Genetic Engineering, and Nanotechnology
Natural killer cells (NK cells) belong to the core of the immune system and play a great potential in tumor immunotherapy ...
Toxic warhead-armed antibody for targeted treatment of glioblastoma
Toxic warhead-armed antibody for targeted treatment of glioblastoma
Diffuse glioma is a malignant primary tumor with multiple growths and extensive infiltration throughout the brain parenchy...
The impact of PARP inhibitors in the whole scenario of Ovarian Cancer management: a Systematic Review and Network Meta-Analysis
The impact of PARP inhibitors in the whole scenario of Ovarian Cancer management: a Systematic Review and Network Meta-Analysis
BackgroundCarboplatin is still the cornerstone of the first-line treatment in advanced Epithelial Ovarian Cancer (aEOC) ma...
Comparative efficacy and tolerability of first-line treatments for untreated, HER2-negative, advanced gastric cancer: systematic review and network meta-analysis
Comparative efficacy and tolerability of first-line treatments for untreated, HER2-negative, advanced gastric cancer: systematic review and network meta-analysis
Gastric cancer (GC) is a disease of global importance. With over 1 million estimated new cases annually, gastric cancer is...
Cancer-associated Fibroblasts in Neoadjuvant Setting for Solid Cancers
Cancer-associated Fibroblasts in Neoadjuvant Setting for Solid Cancers
Cancer-associated fibroblasts (CAFs) are prominent components within the tumor microenvironment (TME) and play significant...
Benefits and risks of PD-1/PD-L1 inhibitors for recurrent small cell lung cancer: A systematic review and meta-analysis
Benefits and risks of PD-1/PD-L1 inhibitors for recurrent small cell lung cancer: A systematic review and meta-analysis
Small cell lung cancer (SCLC) is a neuroendocrine tumor with characteristics such as aggressiveness, early metastasis, rap...
Immune Checkpoint Inhibitors Therapy as the Game-Changing Approach for Pediatric Lymphoma: A Brief Landscape
Immune Checkpoint Inhibitors Therapy as the Game-Changing Approach for Pediatric Lymphoma: A Brief Landscape
Lymphoma, a cancer of lymphoid cells, classified as Hodgkin lymphoma (HL) and non-Hodgkin Lymphoma (NHL), is the third mos...
Tumor budding is a prognostic factor in head and neck squamous cell carcinoma: A comprehensive meta-analysis and trial sequential analysis
Tumor budding is a prognostic factor in head and neck squamous cell carcinoma: A comprehensive meta-analysis and trial sequential analysis
Fábio França Vieira e Silva, DDS, Pathology Expert, M.Sc. in Molecular Oncology, Ph.D. Dentist expert in Pathology and Mol...
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