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[Viewpoint] COVID-19-associated coagulopathy and antithrombotic agents—lessons after 1 year
ACTIV-4, REMAP-CAP, and ATTACC multiplatform trials also studied therapeutic dose anticoagulation in patients with COVID-1...
[Editorial] The evolving promise and potential of gene therapy
In the first half of 2021, we have had mixed news from the field of gene therapy. March saw a halt in bluebird bio's gene ...
[Comment] CPX-351: an attractive option for the treatment of older patients with high-risk or secondary acute myeloid leukaemia
After 5 years of follow-up, the improved overall survival with CPX-351 versus 7+3 was maintained, which supports the previ...
[Comment] Optical or optimal conclusion: pharmacokinetic-guided dosing in haemophilia
Among individuals with haemophilia, the inherited X-linked disorder caused by deficient factor VIII or factor IX and...
[Comment] Iron preparations for iron deficiency anaemia in pregnancy: which treatment is best?
Iron deficiency anaemia is a common clinical problem in pregnant women worldwide. It affects around 15–20% of women ...
[News] Newborn screening for sickle cell disease in Africa
On April 21, 2021, newborn screening for sickle cell disease was launched at Arthur Davison Children's Hospital in N...
[Correspondence] Sustained prothrombotic changes in convalescent patients with COVID-19
We read with great interest the Viewpoint by Leentjens and colleagues1Leentjens J van Haaps TF Wessels PF Schutgens REG Mi...
[In Focus] Trials and tribulations: including women in cancer clinical research
Wellington Blood and Cancer Centre, Capital and Coast District Health Board, Wellington, New ZealandDepartment of Haematol...
[Articles] Perioperative pharmacokinetic-guided factor VIII concentrate dosing in haemophilia (OPTI-CLOT trial): an open-label, multicentre, randomised, controlled trial
Background Dosing of replacement therapy with factor VIII concentrate in patients with haemophilia A...
[Articles] CPX-351 versus 7+3 cytarabine and daunorubicin chemotherapy in older adults with newly diagnosed high-risk or secondary acute myeloid leukaemia: 5-year results of a randomised, open-label, multicentre, phase 3 trial
Background Daunorubicin and cytarabine are used as standard induction chemotherapy for patients with...
[Review] Severe toxicity free survival: physician-derived definitions of unacceptable long-term toxicities following acute lymphocytic leukaemia
1.Bhakta N Liu Q Ness KK et al.The cumulative burden of surviving childhood cancer: an initial report from the St Jude Lif...
[Clinical Picture] Acute lymphoblastic leukaemia presenting as euglycaemic ketoacidosis in a patient with type 1 diabetes
A 21-year-old man presented to the Lausanne University Hospital (CHUV) in August, 2020, with reddened skin lesions o...
[Articles] Iron preparations for women of reproductive age with iron deficiency anaemia in pregnancy (FRIDA): a systematic review and network meta-analysis
1.Systemic iron homeostasis.Physiol Rev. 93: 1721-17412.Barroso F Allard S Kahan BC et al.Prevalence of maternal anaemia a...
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