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Defects in B-lymphopoiesis and B-cell maturation underlie prolonged B-cell depletion in ANCA-associated vasculitis
Defects in B-lymphopoiesis and B-cell maturation underlie prolonged B-cell depletion in ANCA-associated vasculitis
IntroductionAntineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) comprises granulomatosis with polyangii...
2023 EULAR classification criteria for hand osteoarthritis
2023 EULAR classification criteria for hand osteoarthritis
IntroductionHand osteoarthritis (OA) mainly affects the distal interphalangeal (DIP), proximal interphalangeal (PIP) and t...
Racial variability in immune responses only partially explains differential systemic sclerosis disease severity
Racial variability in immune responses only partially explains differential systemic sclerosis disease severity
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From fibrositis to fibromyalgia to nociplastic pain: how rheumatology helped get us here and where do we go from here?
From fibrositis to fibromyalgia to nociplastic pain: how rheumatology helped get us here and where do we go from here?
A historical perspective on our understanding of fibromyalgiaIn 2017, the International Association for the Study of Pain ...
Management of systemic lupus erythematosus: a systematic literature review informing the 2023 update of the EULAR recommendations
Management of systemic lupus erythematosus: a systematic literature review informing the 2023 update of the EULAR recommendations
MethodsWe followed the standardised operating procedures for the development of EULAR-endorsed recommendations and employe...
B-cell depletion in autoimmune diseases
B-cell depletion in autoimmune diseases
B cells have a pivotal function in the pathogenesis of autoimmune diseases, such as rheumatoid arthritis, multiple scleros...
Treatment of early oligoarticular psoriatic arthritis with apremilast: primary outcomes at week 16 from the FOREMOST randomised controlled trial
Treatment of early oligoarticular psoriatic arthritis with apremilast: primary outcomes at week 16 from the FOREMOST randomised controlled trial
Video Abstract Disclaimer: this video summarises a scientific article published by BMJ Publishing Group Limited (BMJ). The...
Correspondence on 'EULAR recommendations for the management of systemic lupus erythematosus: 2023 update by Fanouriakis et al
Correspondence on 'EULAR recommendations for the management of systemic lupus erythematosus: 2023 update by Fanouriakis et al
We read with great interest the new EULAR guidelines1 for the management of systemic lupus erythematosus (SLE), and we app...
Response to: Correspondence on 'EULAR recommendations for the management of systemic lupus erythematosus: 2023 update by Fanouriakis et al
Response to: Correspondence on 'EULAR recommendations for the management of systemic lupus erythematosus: 2023 update by Fanouriakis et al
We thank Drs Roberts et al for their interest in the updated EULAR recommendations for the management of systemic lupus er...
Correspondence on 'Risk of cardiovascular disease with high-dose versus low-dose use of non-steroidal anti-inflammatory drugs in ankylosing spondylitis by Kim et al
Correspondence on 'Risk of cardiovascular disease with high-dose versus low-dose use of non-steroidal anti-inflammatory drugs in ankylosing spondylitis by Kim et al
Kim et al recently published a ‘population-based nationwide cohort study’, a currently popular study type.1 It concludes t...
Referral of patients with suspected polymyalgia rheumatica: how complete is our view of 'planet PMR?
Referral of patients with suspected polymyalgia rheumatica: how complete is our view of 'planet PMR?
Polymyalgia rheumatica (PMR) is the second most common inflammatory rheumatic disease after rheumatoid arthritis in person...
Correction: Ensuring tight control in patients with rheumatoid arthritis treated with targeted therapies during the COVID-19 pandemic using a telehealth strategy
Correction: Ensuring tight control in patients with rheumatoid arthritis treated with targeted therapies during the COVID-19 pandemic using a telehealth strategy
Ingegnoli F, Cincinelli G, Luppino AF, et al. Ensuring tight control in patients with rheumatoid arthritis treated with ta...
Efficacy and safety of sequential therapy with subcutaneous belimumab and one cycle of rituximab in patients with systemic lupus erythematosus: the phase 3, randomised, placebo-controlled BLISS-BELIEVE study
Efficacy and safety of sequential therapy with subcutaneous belimumab and one cycle of rituximab in patients with systemic lupus erythematosus: the phase 3, randomised, placebo-controlled BLISS-BELIEVE study
WHAT IS ALREADY KNOWN ON THIS TOPICAchieving low disease activity in the absence of corticosteroids remains an important t...
HLA-B27 and the role of specific T cell receptors in the pathogenesis of spondyloarthritis
HLA-B27 and the role of specific T cell receptors in the pathogenesis of spondyloarthritis
The pathogenesis of axial spondyloarthritis (axSpA), although not entirely clear yet, is largely based on genes, the stron...
Pathological autoantibody internalisation in myositis
Pathological autoantibody internalisation in myositis
WHAT IS ALREADY KNOWN ON THIS TOPICAutoantibodies targeting intracellular proteins are common in various autoimmune diseas...
Association between premature vascular smooth muscle cells senescence and vascular inflammation in Takayasus arteritis
Association between premature vascular smooth muscle cells senescence and vascular inflammation in Takayasus arteritis
IntroductionTakayasu’s arteritis (TAK) is a chronic large-vessel vasculitis (LVV) characterised by inflammation of the aor...
Paraspinal tophi
Paraspinal tophi
A young adult patient with gout was incidentally found to have a large mass on the right lumbar spine and sacrum during an...
Allogenic bone marrow-derived mesenchymal stromal cell-based therapy for patients with chronic low back pain: a prospective, multicentre, randomised placebo controlled trial (RESPINE study)
Allogenic bone marrow-derived mesenchymal stromal cell-based therapy for patients with chronic low back pain: a prospective, multicentre, randomised placebo controlled trial (RESPINE study)
WHAT IS ALREADY KNOWN ON THIS TOPICMesenchymal stromal cells have been shown to reduce disc inflammation and enhance carti...
Response to: Correspondence on 'Current myositis clinical trials and tribulations by Saygin et al
Response to: Correspondence on 'Current myositis clinical trials and tribulations by Saygin et al
We thank Azevedo et al 1 for their correspondence in response to the publication of our viewpoint entitled ‘Myositis Clini...
Dysregulation of immune checkpoint molecules as a characteristic of autoimmune congenital heart block
Dysregulation of immune checkpoint molecules as a characteristic of autoimmune congenital heart block
Autoimmune congenital heart block (CHB) represents a severe manifestation of neonatal lupus syndrome due to placental tran...
Nasal tophi
Nasal tophi
A 39-year-old man presented at our hospital due to recurrent swelling, redness and pain in his nasal area over the past 2 ...
Sacroiliac radiographic progression over 10 years in axSpA: data from the DESIR inception cohort
Sacroiliac radiographic progression over 10 years in axSpA: data from the DESIR inception cohort
WHAT IS ALREADY KNOWN ON THIS TOPICInformation about the likelihood of radiographic sacroiliitis over time in patients wit...
Systemic inflammatory cytokine profiles in patients with gout during flare, intercritical and treat-to-target phases: TNFSF14 as new biomarker
Systemic inflammatory cytokine profiles in patients with gout during flare, intercritical and treat-to-target phases: TNFSF14 as new biomarker
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Retraction: PKC{delta} null mutations in a mouse model of osteoarthritis alter osteoarthritic pain independently of joint pathology by augmenting NGF/TrkA-induced axonal outgrowth
Retraction: PKC{delta} null mutations in a mouse model of osteoarthritis alter osteoarthritic pain independently of joint pathology by augmenting NGF/TrkA-induced axonal outgrowth
Kc R, Li X, Kroin JS, et al. PKCδ null mutations in a mouse model of osteoarthritis alter osteoarthritic pain independentl...
Annals of the Rheumatic Diseases collection on epigenetics: from three dimensional chromatin organisation to microRNA
Annals of the Rheumatic Diseases collection on epigenetics: from three dimensional chromatin organisation to microRNA
IntroductionThe term ‘epigenetics’ describes various mechanisms that in their entirety control the gene expression of a ce...
Current myositis clinical trials and tribulations
Current myositis clinical trials and tribulations
With improved understanding of disease pathogenesis and availability of outcome measures, there has been a remarkable incr...
Immune response to post-translationally modified proteins in rheumatoid arthritis: what makes it special?
Immune response to post-translationally modified proteins in rheumatoid arthritis: what makes it special?
Rheumatoid arthritis (RA) exhibits common characteristics with numerous other autoimmune diseases, including the presence ...
The role of DNA in the pathogenesis of SLE: DNA as a molecular chameleon
The role of DNA in the pathogenesis of SLE: DNA as a molecular chameleon
Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterised by antibodies to DNA (anti-DNA) and ot...
Gender equity in global rheumatology awards
Gender equity in global rheumatology awards
Globally, there has been a growing interest in addressing gender disparities in leadership positions within rheumatology,1...
Power Doppler signal at the enthesis and bone erosions are the most discriminative OMERACT ultrasound lesions for SpA: results from the DEUS (Defining Enthesitis on Ultrasound in Spondyloarthritis) multicentre study
Power Doppler signal at the enthesis and bone erosions are the most discriminative OMERACT ultrasound lesions for SpA: results from the DEUS (Defining Enthesitis on Ultrasound in Spondyloarthritis) multicentre study
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Cleara...
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