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DPM1 expression as a potential prognostic tumor marker in oral squamous cell carcinoma
Head and neck cancer ranks as the sixth most prevalent cancer globally, with about 950,000 new cases and 480,000 deaths re...
TWF1 promotes tumor progression in head and neck squamous cell carcinoma via AKT phosphorylation
Head and neck squamous cell carcinoma (HNSCC) is a globally prevalent malignancy associated with high incidence and mortal...
Elaeodendron buchananii (Loes.) Loes. stem bark: Unveiling the phytochemical profiles and selective bioactivity to combat tongue cancer
Oral cancer is one of the malignancies most closely associated with chronic inflammation. Inflammatory mediators in the tu...
Patterns of circulating autoantibodies against desmoglein-1 and desmoglein-3 in the progression of oral lichen planus: A scoping review
Oral lichen planus (OLP) is a chronic inflammatory mucosal disorder characterized by immune dysregulation and an elevated ...
Exercise modulates local inflammation and tissue loss in experimental periodontitis: A histomorphometric and immunohistochemical study in ra
ObjectiveThis study aimed to investigate the effects of resistance exercise on the progression of periodontal disease in r...
Action mechanisms of progesterone in managing bone loss in periodontitis: An in vitro study
Progesterone (PG) is a C21 steroid hormone that is synthesised from cholesterol via the pregnenolone pathway (Kolatorova, ...
MIR375 hypermethylation as a prognostic predictor for head and neck squamous cell carcinoma: Insights from The Cancer Genome Atlas (TCGA)
Head and neck cancer (HNC) is among the most common neoplasms worldwide, with global estimates indicating over 1.7 million...
Gingival crevicular fluid levels of soluble triggering receptor expressed on myeloid cells 1 in chronic periodontitis: A systematic review and meta-analysis
Volume 181, January 2026, 106440Author links open overlay panel, , , , Highlights•Higher Gingival Crevicular Fluid sTREM-1...
Traditional Chinese medicine Pudilan synergizes with smc gene to impair cell growth and exopolysaccharides synthesis of Streptococcus mutans
Dental caries is a progressive disease of the tooth’s hard tissues. Untreated permanent dental caries remains the most com...
Extracellular vesicles derived from Filifactor alocis induce interleukin-6 production in osteoblasts via Toll-like receptor 2 signaling
ObjectiveThis study aimed to investigate the effect of the periodontal bacterium Filifactor alocis on proinflammatory cyto...
NFIC activates DEPTOR and blocks mTOR signaling to inhibit glycolysis and immune escape in oral squamous cell carcinoma
Oral squamous cell carcinoma (OSCC) represents the most common type of head and neck squamous cell carcinoma (HNSCC), whic...
Influence of head and neck radiotherapy doses on apical periodontitis progression: An animal-based study
Head and neck cancer comprises malignant tumors affecting the oral cavity, pharynx, larynx, paranasal sinuses, and nasal c...
Novel missense mutations in the tumor necrosis factor domain of Ectodysplasin-A cause non-syndromic tooth agenesis in two Chinese families
Tooth agenesis (OMIM #106600) is a common congenital craniofacial developmental anomaly, with the prevalence (excluding th...
Accuracy of dental age estimation methods in children with chromosomal syndromes: A systematic review and network meta-analysis
In dentistry, particularly in orthodontics, dental age estimation (DAE) combined with skeletal age assists the clinician i...
The microRNA-34b-3p/SOX5 axis regulates cellular activities and tumor angiogenesis in oral squamous cell carcinoma
Oral squamous cell carcinoma (OSCC) represents the most prevalent form of head and neck cancer, accounting for over 90 % o...
Biomechanical impact of tooth root morphology to inform dental implant design
The tooth implant model used for this study is available on SketchFab (Hq3dmod, 2022) for download. All other original dat...
Temporal dynamics and predictive modeling of oral epithelial dysplasia features during carcinogenesis
Oral squamous cell carcinoma (OSCC) remains a significant global health challenge, with an estimated 378,000 new cases in ...
In vivo immunological evaluation of indomethacin and omega-3 nanocapsules for the treatment of rheumatoid arthritis in the temporomandibular joints of rats
The temporomandibular joint (TMJ) is a synovial joint that connects the condylar process of the mandible to the mandibular...
Effect of high-lipid environment on human gingival fibroblast on titanium surface: An in-vitro study
Peri-implantitis is a disease manifested by peri-implant inflammation include the loss of peri-implant alveolar bone, whic...
RAW 264.7-derived exosomal miR-494–3p regulates inflammation and osteogenic differentiation of human periodontal ligament stem cells through regulating CAMK2D
Periodontitis is a prevalent chronic inflammatory disease characterized by the progressive destruction of tooth-supporting...
Pathways of the vitamin D receptor gene and dental caries: A systematic review and meta-analysis
Caries is described as the localized demineralization of dental tissues caused by acid produced from free sugars’ bacteria...
Systemic administration of polyphenols from dealcoholized red wine reduces inflammation and bone resorption in established apical periodontitis in male rats
Apical periodontitis is an inflammatory disease that affects the periapical tissues in response to a polymicrobial infecti...
Whole-genome sequencing analysis of Cutibacterium spp. recovered from health care-associated endodontic infections
Cutibacterium acnes is a Gram-positive species (Aubin et al., 2017), three subspecies and six phylotypes: C. acnes subsp. ...
Orofacial pain symptoms in sleep bruxer or non-sleep bruxer: Insights from a population-based survey of puerperal women
The International Association for Study of Pain defines pain as an unpleasant sensory and emotional experience associated ...
STING regulates porphyromonas gingivalis lipopolysaccharide-induced pyroptosis and inflammatory response through the NF-κB/NLRP3 signaling pathway in human gingival fibroblasts
Periodontitis, commonly known as periodontal disease or gingival disease, is a chronic inflammatory condition that affects...
Impaction risk increases significantly with each year of late third molar development in Western Canadian youths
Volume 173, May 2025, 106214Author links open overlay panel, , , Highlights•Late-developing M3s are statistically more lik...
Botulinum toxin type A inhibits hyperalgesia in the rat masseter muscle in a carrageenan model of myofascial pain
Botulinum toxin type A (BoNT-A) is a subtype of a potent neurotoxin secreted by the bacterium Clostridium botulinum. BoNT-...
Change and significance of connexin 43 in saliva extracellular vesicles from oral lichen planus patients
ObjectivesThis study aims to explore whether Connexin 43 (Cx43) in salivary extracellular vesicles (EVs) can serve as a bi...
Spatially resolved composition of bovine dental enamel in permanent incisors
In vitro research in Dentistry ideally uses human teeth as the first option, due to the excellent substrate for testing me...
Association between agenesis of permanent teeth and other dental anomalies in nonsyndromic patients: Systematic review
Hypodontia is the most common craniofacial anomaly and may be associated with genetic syndromes or isolated, with both gen...
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