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Methylation of Coproporphyrin as a Protective Mechanism in Mycobacteria under Adverse Conditions
Methylation of Coproporphyrin as a Protective Mechanism in Mycobacteria under Adverse Conditions
The transition of active Mycolicibacterium smegmatis cells to a dormant state under acidification conditions is accompanie...
Application of MF3 Microbial Recombinant Protein in Refolding of Plant Chitinase
Application of MF3 Microbial Recombinant Protein in Refolding of Plant Chitinase
Expression of recombinant proteins is important for studying their biological functions. For the primary description of pr...
Protein Engineering of Lactate Oxidase
Protein Engineering of Lactate Oxidase
Lactate oxidase is a practically important enzyme widely used to detect L-lactate in medical diagnostics and in the food i...
High Throughput Screening in Drug Discovery: Problems and Solutions
High Throughput Screening in Drug Discovery: Problems and Solutions
World-wide introduction of high throughput screening (HTS) methods in drug discovery research did not result in the increa...
Strategies of N-Glycosidic Bond Cleavage by DNA Repair Enzymes
Strategies of N-Glycosidic Bond Cleavage by DNA Repair Enzymes
DNA glycosylases are enzymes that hydrolyze the N-glycosidic bond of damaged nucleotides, initiating the process of base e...
Computer Modeling of the Mechanisms of Enzymatic Reactions: Lessons from 20 Years of Practice
Computer Modeling of the Mechanisms of Enzymatic Reactions: Lessons from 20 Years of Practice
The combined quantum mechanics/molecular mechanics method is most often used to describe the molecular mechanisms of enzym...
Modern Methods of Aptamer Chemical Modification and Principles of Aptamer Library Selection
Modern Methods of Aptamer Chemical Modification and Principles of Aptamer Library Selection
Aptamers are promising for a wide application range in biomedicine and various diagnostic systems due to their unique prop...
Post-Translational Modifications of the Sulfhydryl Group of the Cysteine Residue of Glyceraldehyde-3-phosphate Dehydrogenase
Post-Translational Modifications of the Sulfhydryl Group of the Cysteine Residue of Glyceraldehyde-3-phosphate Dehydrogenase
The main types of oxidative post-translational modifications of the glycolytic enzyme glyceraldehyde-3-phosphate dehydroge...
Hydrodechlorination of Diclofenac in an Aqueous Solution over Pd/ZrO2 and Pd/ZrO2SiO2 Catalysts
Hydrodechlorination of Diclofenac in an Aqueous Solution over Pd/ZrO2 and Pd/ZrO2SiO2 Catalysts
Pd/ZrO2 and Pd/ZrO2SiO2 catalysts prepared by wet impregnation and reduced with H2 under mild (30°C, aqueous suspensi...
Antibacterial Activity of Amphiphiles Based on Indolyl-3-Carboxylic Acids and L-Lysine with an Ethylenediamine Linker
Antibacterial Activity of Amphiphiles Based on Indolyl-3-Carboxylic Acids and L-Lysine with an Ethylenediamine Linker
Recently, due to the growth in bacterial infections resistant to antibiotics, there is an urgent need for developing alter...
Regulation of Enzyme-Dependent Lysis of Microbial Cells: Is the Effector Target an Enzyme or Substrate?
Regulation of Enzyme-Dependent Lysis of Microbial Cells: Is the Effector Target an Enzyme or Substrate?
In this study, an attempt is made to analyze the published data regarding the effectors of bacterial lysis in the presence...
Neuraminidase Inhibitory Activities of Some Alcoholic Plant Extracts and Chemical Compounds
Neuraminidase Inhibitory Activities of Some Alcoholic Plant Extracts and Chemical Compounds
In today’s world, disease rates are increasing day after day because of environmental factors, lifestyles and techno...
Coelenterazine-Dependent Luciferases: Properties and Application in Molecular Analysis
Coelenterazine-Dependent Luciferases: Properties and Application in Molecular Analysis
This review presents the data on the structure of bioluminescent systems of marine animals that use coelenterazine-depende...
Identification of “Hot Spots” to Improve Maturation of the moxSAASoti Fluorescent Protein at 37°C
Identification of “Hot Spots” to Improve Maturation of the moxSAASoti Fluorescent Protein at 37°C
A search for amino acid residues, whose replacement could contribute to the optimal maturation of the moxSAASoti fluoresce...
Biopolymer Controlled Release Systems Based on Hydrolyzed Collagen: Cryoforming, Structure, and Properties
Biopolymer Controlled Release Systems Based on Hydrolyzed Collagen: Cryoforming, Structure, and Properties
Biopolymer materials based on natural collagen (gelatin, hydrolyzed collagen) are widely used in the food, pharmaceutical,...
Immunofluorescence Analysis of Estrogen Receptors Alpha Expression in Non-Small Cell Lung Cancer Tissue
Immunofluorescence Analysis of Estrogen Receptors Alpha Expression in Non-Small Cell Lung Cancer Tissue
A quantitative assessment of the expression of estrogen receptors alpha (ERα) is carried out in 115 samples of non-sm...
New Magnetic Colloidal Systems Based on Biomimetic Polycomplexes
New Magnetic Colloidal Systems Based on Biomimetic Polycomplexes
This paper presents new colloidal systems that have prospects for use as carriers of medicinal compounds and are polymer c...
Huntingtin, the Major Factor in Huntington’s Disease Development. Main Functions and Intracellular Proteolysis
Huntingtin, the Major Factor in Huntington’s Disease Development. Main Functions and Intracellular Proteolysis
This review is devoted to the consideration of pathological intracellular mechanisms characteristic of Huntington’s ...
Lattice Tilings of a Plane into Polyominoes and Molecular Layers in Crystal Structures: Structural Class cm, Z = 2(m)
Lattice Tilings of a Plane into Polyominoes and Molecular Layers in Crystal Structures: Structural Class cm, Z = 2(m)
Lattice tilings of a plane into polyominoes are constructed for N from 3 to 12, where N is the order of the packing space....
The Influence of Polyvinyl Alcohol on the Stability of Aqueous Dispersions of Nanodiamonds
The Influence of Polyvinyl Alcohol on the Stability of Aqueous Dispersions of Nanodiamonds
The stability of aqueous dispersions of detonation nanodiamonds (NDs) in the presence of polyvinyl alcohol (PVA) is studie...
Modelling Silver Cluster Complexes with the Antibacterial Medication Dioxidine
Modelling Silver Cluster Complexes with the Antibacterial Medication Dioxidine
The structures of small silver clusters (Agn, n = 1–3, 13) and their complexes with molecules of the antibacterial d...
Spectrophotometric Determination of Copper(II) in Soil in the Form of a Pyrogallol Red Complex in the Presence of Surfactants
Spectrophotometric Determination of Copper(II) in Soil in the Form of a Pyrogallol Red Complex in the Presence of Surfactants
A spectrophotometric procedure for the quantitative determination of copper(II) by a reaction of complex formation with py...
Rheology of Structured Liquids: Dependence of Dynamic Moduli on Strain Amplitude
Rheology of Structured Liquids: Dependence of Dynamic Moduli on Strain Amplitude
A new interpretation is proposed for the dependence of dynamic moduli on the strain amplitude in the course of shear vibra...
Simultaneous Determination of Chlorhexidine, p-Chloroaniline, Triclosan, Dibutyl Phthalate, and Ionol in an Antibacterial Liquid by HPLC with Spectrophotometric Detection
Simultaneous Determination of Chlorhexidine, p-Chloroaniline, Triclosan, Dibutyl Phthalate, and Ionol in an Antibacterial Liquid by HPLC with Spectrophotometric Detection
This article studies the development of a simple chromatographic method for the simultaneous determination of well-known a...
Evaluation of the Nutritional Value, Toxins and Pollutants in Mazandaran Rice and Detection of the Rice Health Level
Evaluation of the Nutritional Value, Toxins and Pollutants in Mazandaran Rice and Detection of the Rice Health Level
As insecticides, fungicides, heavy metals, and aflatoxins enter the food chain, they cause adverse effects on living organ...
Comparative Analysis of the Capabilities of Spectral Methods in Studying the Internal Rotation of Compounds of the Benzoic Series
Comparative Analysis of the Capabilities of Spectral Methods in Studying the Internal Rotation of Compounds of the Benzoic Series
In this review the methods used to study internal rotation (IR) in the ground (S0) and excited (S1) electronic states for ...
Synthesis and Biological Evaluation Studies of Novel 1,3,4-Oxadiazole and Benzo[d]imidazole Scaffolds as Promising Antimicrobial Agents
Synthesis and Biological Evaluation Studies of Novel 1,3,4-Oxadiazole and Benzo[d]imidazole Scaffolds as Promising Antimicrobial Agents
We prepared a novel series of 1,3,4-oxadiazole and benzo[d]imidazolecontaining fi fteen new connections to develop potenti...
Solubility Study of Amlodipine Besylate in Ethylene Glycol + 2-Propanol Mixtures at Different Temperatures
Solubility Study of Amlodipine Besylate in Ethylene Glycol + 2-Propanol Mixtures at Different Temperatures
Solubility behavior of amlodipine besylate (ADB) was investigated in the binary mixtures of ethylene glycol + 2-propanol a...
Rheology of Structured Liquids: Newtonian Behavior
Rheology of Structured Liquids: Newtonian Behavior
In this paper, we analyze the behavior of low-molecular-weight non-Newtonian fluids (liquid paraffin, silicone oil, and FC...
Quantitative Immunofluorescence Evaluation of PD-L1 Expression in Non-Muscle-Invasive and Muscle-Invasive Urothelial Bladder Cancer
Quantitative Immunofluorescence Evaluation of PD-L1 Expression in Non-Muscle-Invasive and Muscle-Invasive Urothelial Bladder Cancer
The expression of PD-L1 protein is quantified in 56 samples of urothelial bladder cancer (BC). PD-L1 expression is detecte...
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